Aqueous Solution Equilibria and Spectral Features of Copper Complexes with Tripeptides Containing Glycine or Sarcosine and Leucine or Phenylalanine

Copper(II) complexes of glycyl-L-leucyl-L-histidine (GLH), sarcosyl-L-leucyl-L-histidine (Sar-LH), glycyl-L-phenylalanyl-L-histidine (GFH) and sarcosyl-L-phenylalanyl-L-histidine (Sar-FH) have potential anti-inflammatory activity, which can help to alleviate the symptoms associated with rheumatoid arthritis (RA). From pH 2–11, the MLH, ML, MLH-1 and MLH-2 species formed. The combination of species for each ligand was different, except at the physiological pH, where CuLH-2 predominated for all ligands. The prevalence of this species was supported by EPR, ultraviolet-visible spectrophotometry, and mass spectrometry, which suggested a square planar CuN4 coordination. All ligands have the same basicity for the amine and imidazole-N, but the methyl group of sarcosine decreased the stability of MLH and MLH-2 by 0.1–0.34 and 0.46–0.48 log units, respectively. Phenylalanine increased the stability of MLH and MLH-2 by 0.05–0.29 and 1.19–1.21 log units, respectively. For all ligands, 1H NMR identified two coordination modes for MLH, where copper(II) coordinates via the amine-N and neighboring carbonyl-O, as well as via the imidazole-N and carboxyl-O. EPR spectroscopy identified the MLH, ML and MLH-2 species for Cu-Sar-LH and suggested a CuN2O2 chromophore for ML. DFT calculations with water as a solvent confirmed the proposed coordination modes of each species at the B3LYP level combined with 6-31++G**

VizieR Online Data Catalog: Code to compute spectral line profile indicators (Lanza+, 2018)

A computer code (procedure) written in Interactive Data Language (IDL) to compute the spectral line profile indicators used in the above research article starting from the fits files provided by the data reduction software (DRS) of HARPS or HARPS-N. The procedure takes the cross-correlation function (CCF) files provided by the DRS as an input. An example for the input files and the corresponding output file is provided with the sole purpose of allowing to test the proper compilation and running of the procedure. Details on an auxiliary source file (mpfit.pro) required for compilation are provided in the header of the procedure file and in Appendix A of the above mentioned article. Interested users are warmly recommended to read them before compiling and running the procedure. (Notes: 4 data files)

HADES RV program with HARPS-N at the TNG GJ 3998: An early M-dwarf hosting a system of super-Earths

Context. Many efforts are currently made to detect Earth-like planets around low-mass stars in almost every extra-solar planet search. M dwarfs are considered ideal targets for Doppler radial velocity searches because their low masses and luminosities make low-mass planets orbiting in these stars' habitable zones more easily detectable than those around higher mass stars. Nonetheless, the frequency statistics of low-mass planets hosted by low-mass stars remains poorly constrained. Aims: Our M-dwarf radial velocity monitoring with HARPS-N within the collaboration between the Global architectures of Planetary Systems (GAPS) project, the Institut de Ciències de l'Espai/CSIC-IEEC (ICE) and the Instituto de Astrofísica de Canarias (IAC) can provide a major contribution to the widening of the current statistics through the in-depth analysis of accurate radial velocity observations in a narrow range of spectral sub-types (79 stars, between dM0 to dM3). Spectral accuracy will enable us to reach the precision needed to detect small planets with a few Earth masses. Our survey will contribute to the surveys devoted to the search for planets around M-dwarfs, mainly focused on the M-dwarf population of the northern emisphere, for which we will provide an estimate of the planet occurrence. Methods: We present here a long-duration radial velocity monitoring of the M1 dwarf star GJ 3998 with HARPS-N to identify periodic signals in the data. Almost simultaneous photometric observations were carried out within the APACHE and EXORAP programs to characterize the stellar activity and to distinguish those due to activity and to the presence of planetary companions from the periodic signals. We ran a Markov chain Monte Carlo simulation and used a Bayesian model selection to determine the number of planets in this system, to estimate their orbital parameters and minimum mass, and to properly treat the activity noise. Results: The radial velocities have a dispersion in excess of their internal errors due to at least four superimposed signals with periods of 30.7, 13.7, 42.5, and 2.65 days. Our data are well described by a two-planet Keplerian (13.7 d and 2.65 d) and a fit with two sinusoidal functions (stellar activity, 30.7 d and 42.5 d). The analysis of spectral indexes based on Ca II H & K and Hα lines demonstrates that the periods of 30.7 and 42.5 days are due to chromospheric inhomogeneities modulated by stellar rotation and differential rotation. This result is supported by photometry and is consistent with the results on differential rotation of M stars obtained with Kepler. The shorter periods of 13.74 ± 0.02 d and 2.6498 ± 0.0008 d are well explained with the presence of two planets, with masses of at least 6.26_(-0.76)^(+0.79) M⊕ and 2.47 ± 0.27 M⊕ and distances of 0.089 AU and 0.029 AU from the host, respectively. -- Based on: observations made with the Italian Telescopio Nazionale Galileo (TNG), operated on the island of La Palma by the INAF - Fundación Galileo Galilei at the Roche de Los Muchachos Observatory of the Instituto de Astrofísica de Canarias (IAC); photometric observations made with the APACHE array located at the Astronomical Observatory of the Aosta Valley; photometric observations made with the robotic telescope APT2 (within the EXORAP program) located at Serra La Nave on Mt. Etna. http://www.oact.inaf.it/exoit/EXO-IT/Projects/Entries/2011/12/27_GAPS.html</A

The GAPS Programme with HARPS-N at TNG. XII. Characterization of the planetary system around HD 108874

In order to understand the observed physical and orbital diversity of extrasolar planetary systems, a full investigation of these objects and of their host stars is necessary. Within this field, one of the main purposes of the GAPS observing project with HARPS-N at TNG is to provide a more detailed characterization of already known systems. In this framework we monitored the star, hosting two giant planets, HD 108874, with HARPS-N for three years in order to refine the orbits, to improve the dynamical study and to search for additional low-mass planets in close orbits. We subtracted the radial velocity (RV) signal due to the known outer planets, finding a clear modulation of 40.2 d period. We analysed the correlation between RV residuals and the activity indicators and modelled the magnetic activity with a dedicated code. Our analysis suggests that the 40.2 d periodicity is a signature of the rotation period of the star. A refined orbital solution is provided, revealing that the system is close to a mean motion resonance of about 9:2, in a stable configuration over 1 Gyr. Stable orbits for low-mass planets are limited to regions very close to the star or far from it. Our data exclude super-Earths with Msini ≳ 5M⊕ within 0.4 AU and objects with Msini ≳ 2M⊕ with orbital periods of a few days. Finally we put constraints on the habitable zone of the system, assuming the presence of an exomoon orbiting the inner giant planet. Based on observations made with the Italian Telescopio Nazionale Galileo (TNG) operated on the island of La Palma by the Fundación Galileo Galilei of the INAF at the Spanish Observatorio del Roque de los Muchachos of the IAC in the frame of the programme Global Architecture of Planetary Systems (GAPS).Table A.1 is also available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/599/A90</A

The GAPS programme with HARPS-N at TNG. XVI. Measurement of the Rossiter-McLaughlin effect of transiting planetary systems HAT-P-3, HAT-P-12, HAT-P-22, WASP-39, and WASP-60

Context. The measurement of the orbital obliquity of hot Jupiters with different physical characteristics can provide clues to the mechanisms of migration and orbital evolution of this particular class of giant exoplanets. Aims: We aim to derive the degree of alignment between planetary orbit and stellar spin angular momentum vectors and look for possible links with other orbital and fundamental physical parameters of the star-planet system. We focus on the characterisation of five transiting planetary systems (HAT-P-3, HAT-P-12, HAT-P-22, WASP-39, and WASP-60) and the determination of their sky-projected planet orbital obliquity through the measurement of the Rossiter-McLaughlin effect. Methods: We used HARPS-N high-precision radial velocity measurements, gathered during transit events, to measure the Rossiter-McLaughlin effect in the target systems and determine the sky-projected angle between the planetary orbital plane and stellar equator. The characterisation of stellar atmospheric parameters was performed by exploiting the HARPS-N spectra, using line equivalent width ratios and spectral synthesis methods. Photometric parameters of the five transiting exoplanets were re-analysed through 17 new light curves, obtained with an array of medium-class telescopes, and other light curves from the literature. Survey-time-series photometric data were analysed for determining the rotation periods of the five stars and their spin inclination. Results: From the analysis of the Rossiter-McLaughlin effect we derived a sky-projected obliquity of λ = 21.2° ± 8.7°, λ = -54°-13°+41°, λ = -2.1° ± 3.0°, λ = 0° ± 11°, and λ = -129° ± 17° for HAT-P-3 b, HAT-P-12 b, HAT-P-22 b, WASP-39 b, and WASP-60 b, respectively. The latter value indicates that WASP-60 b is moving on a retrograde orbit. These values represent the first measurements of λ for the five exoplanetary systems under study. The stellar activity of HAT-P-22 indicates a rotation period of 28.7 ± 0.4 days, which allowed us to estimate the true misalignment angle of HAT-P-22 b, ψ = 24° ± 18°. The revision of the physical parameters of the five exoplanetary systems returned values that are fully compatible with those existing in the literature. The exception to this is the WASP-60 system, for which, based on higher quality spectroscopic and photometric data, we found a more massive and younger star and a larger and hotter planet. Tables of the light curve and radial velocity data are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/613/A4