ACUTE VIRAL HEPATITIS IN DRUG ADDICTED PATIENTS

Twenty-five patients with acute viral hepatitis and drug abuse (heroin) aged between 15 and 30 years were studied. They were hospitalized in the Department of Infectious Diseases and Epidemiology, Medical University of Varna, during the period from January till October, 1998. The following types of viral hepatitis were established: acute viral hepatitis A (AVH-A) - in 7 patients, acute viral hepatitis В (AVH-B) - in two, acute viral hepatitis С (AHV-C) - in 6, non-defined AVH - in 9, and toxic hepatitis - in one patient. Most cases with AVH-C were clinically clearly manifested and there were no diagnostic difficulties. Probably, the non-defined AVH cases belonged to AVH-C infection but they remained not proved because of the absent diagnostic opportunities

ACUTE VIRAL HEPATITIS С

Thirteen patients of different age groups were examined. They presented with clinico-biochemical data about acute viral hepatitis serologically decoded as acute viral hepatitis C. In 9 cases an evidence of inoculative manipulations (in 6 venous drug abusers and in 3 cases after surgical interventions) was established. The course of the disease was not very severe. In one patient it was even slight. There was a tendency towards a chronic course in 5 cases. In two patients the catamnestic folllowing-up revealed a histological evidence of chronic viral hepatitis C. Interferon therapy was administered

Constacyclic codes as invariant subspaces

AbstractConstacyclic codes are generalizations of the familiar linear cyclic codes. In this paper constacyclic codes over a finite field F are regarded as invariant subspaces of Fn with respect to a suitable linear operator. By applying standard techniques from linear algebra one can derive properties of these codes which generalize several well-known results for cyclic codes, such as the various lower bounds for the minimum distance

PECULIARITIES OF THE EPIDEMIC PROCESS OF EPIDEMIC PAROTITIS UNDER THE CONDITIONS OF MASS IMMUNOPROPHYLAXIS

Some specific features of the mumps epidemic process under the conditions of mass immunoprevention were analyzed. Incidence rates were higher when there was a remoteness of the primary immunization by live parotitis vaccine. Certain opportunities for amending the epidemic control with this vaccine to avoid infection were emphasized

EPIDEMIOLOGICAL, CLINICAL AND LABORATORY PECULIARITIES OF AN EPIDEMIC OF ACUTE VIRAL HEPATITIS DURING 1990-1991 IN THE REGION OF VARNA

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Families of twisted tensor product codes

Using geometric properties of the variety \cV_{r,t}, the image under the Grassmannian map of a Desarguesian $(t-1)$-spread of \PG(rt-1,q), we introduce error correcting codes related to the twisted tensor product construction, producing several families of constacyclic codes. We exactly determine the parameters of these codes and characterise the words of minimum weight.Comment: Keywords: Segre Product, Veronesean, Grassmannian, Desarguesian spread, Subgeometry, Twisted Product, Constacyclic error correcting code, Minimum weigh

Differences in energy balance-related behaviours in European preschool children: The ToyBox-study

Background: The aim of the current study was to compare levels of energy balance-related behaviours (physical activity, sedentary behaviour, and dietary behaviours (more specifically water consumption, sugar-sweetened beverage consumption and unhealthy snacking)) in four- to six-year-old preschoolers from six European countries (Belgium, Bulgaria, Germany, Greece, Poland, and Spain) within the ToyBox cross-sectional study. Methods: A sample of 4,045 preschoolers (4.77 ± 0.43 years; 52.2% boys) had valid physical activity data (steps per day), parents of 8,117 preschoolers (4.78 ± 0.46 years; 53.0% boys) completed a parental questionnaire with questions on sedentary behaviours (television viewing, computer use, and quiet play), and parents of 7,244 preschoolers (4.77 ± 0.44 years; 52.0% boys) completed a food frequency questionnaire with questions on water consumption, sugar-sweetened beverage consumption and unhealthy snacking. Results: The highest levels of physical activity were found in Spain (12,669 steps/day on weekdays), while the lowest levels were found in Bulgaria and Greece (9,777 and 9,656 steps/day on weekdays, respectively). German preschoolers spent the least amount of time in television viewing (43.3 min/day on weekdays), while Greek preschoolers spent the most time in television viewing (88.5 min/day on weekdays). A considerable amount of time was spent in quiet play in all countries, with the highest levels in Poland (104.9 min/day on weekdays), and the lowest levels in Spain (60.4 min/day on weekdays). Belgian, German, and Polish preschoolers had the lowest intakes of water and the highest intakes of sugar-sweetened beverages. The intake of snacks was the highest in Belgian preschoolers (73.1 g/day) and the lowest in Greek preschoolers (53.3 g/day). Conclusions: Across six European countries, differences in preschoolers'' energy balance-related behaviours were found. Future interventions should target European preschoolers '' energy balance- related behaviours simultaneously, but should apply country-specific adaptations

Effect and process evaluation of a kindergarten-based, family-involved cluster randomised controlled trial in six European countries on four- to six-year-old children's steps per day: The ToyBox-study

Background: The ToyBox-intervention is a theory- and evidence-based intervention delivered in kindergartens to improve four- to six-year-old children''s energy balance-related behaviours and prevent obesity. The current study aimed to (1) examine the effect of the ToyBox-intervention on increasing European four- to six-year-old children'' steps per day, and (2) examine if a higher process evaluation score from teachers and parents was related to a more favourable effect on steps per day. Methods: A sample of 2438 four- to six-year-old children (51.9% boys, mean age 4.75±0.43years) from 6 European countries (Belgium, Bulgaria, Germany, Greece, Poland and Spain) wore a motion sensor (pedometer or accelerometer) for a minimum of two weekdays and one weekend day both at baseline and follow-up to objectively measure their steps per day. Kindergarten teachers implemented the physical activity component of the ToyBox-intervention for 6 weeks in total, with a focus on (1) environmental changes in the classroom, (2) the child performing the actual behaviour and (3) classroom activities. Children''s parents received newsletters, tip cards and posters. To assess intervention effects, multilevel repeated measures analyses were conducted for the total sample and the six intervention countries separately. In addition, process evaluation questionnaires were used to calculate a total process evaluation score (with implementation and satisfaction as a part of the overall score) for teachers and parents which was then linked with the physical activity outcomes. Results: No significant intervention effects on four- to six-year-old children'' steps per weekday, steps per weekend day and steps per average day were found, both in the total sample and in the country-specific samples (all p>0.05). In general, the intervention effects on steps per day were least favourable in four- to six-year-old children with a low teachers process evaluation score and most favourable in four- to six-year-old children with a high teachers process evaluation score. No differences in intervention effects were found for a low, medium or high parents'' process evaluation score. Conclusion: The physical activity component of the ToyBox-intervention had no overall effect on four- to six-year-old children'' steps per day. However, the process evaluation scores showed that kindergarten teachers that implemented the physical activity component of the ToyBox-intervention as planned and were satisfied with the physical activity component led to favourable effects on children''s steps per day. Strategies to motivate, actively involve and engage the kindergarten teachers and parents/caregivers are needed to induce larger effects

Review Methods of Neuropsychological Screening of Cognitive Functions and Features of Their Application in the Study of Patients with HIV Infection and Acquired Immune Deficiency Syndrome

Куков Калоян, доктор психологии, клинический психолог, Многопрофильная больница активного лечения (МБАЛ) «Света Марина», г. Варна, Республика Болгария, [email protected] Радкова Диана Милена, доцент, доктор медицины, доктор, руководитель отделения инфекционных и паразитарных болезней, Многопрофильная больница активного лечения (МБАЛ) «Света Марина», УНС по инфекционным болезням и паразитология кафедры инфекционных, паразитарных болезней и дерматовенерологии, Медицинский университет им. проф. Параскева Стоянова, г. Варна, Республика Болгария, [email protected]; [email protected] Николова Даниела, доктор, главный ассистент, заведующая Первой клиникой инфекционных и паразитарных болезней, Многопрофильная больница активного лечения (МБАЛ) «Света Марина», г. Варна, Республика Болгария, [email protected] K. Kukov1, [email protected] D. Radkova1,2, [email protected]; [email protected] D. Nikolova1, [email protected] 1 Hospital St. Marina, Varna, Republic of Bulgaria 2 Medical Universityof Varna, Varna, Republic of BulgariaРассмотрены задачи клинической нейропсихологии по оценке когнитивных наруше- ний вследствие повреждения головного мозга и/или его дисфункции. Описаны современные и наиболее часто использующиеся методики и диагностические комплексы (батареи нейропсихологической диагностики), позволяющие определить характер сильных и слабых сторон индивидуального когнитивного функционирования, определяющего эффективность повседневной деятельности. Приводятся описания состава таких батарей, показания к применению. Отдельно описаны требования к исследованию нейрокогнитивного статуса пациентов с вирусом иммунодефицита человека (ВИЧ) и синдромом приобретенного иммунодефицита (СПИД) и принципы организации исследования. The paper considered clinical neuropsychology problems which are focused on the evaluation of cognitive impairment due to brain damage and/or dysfunction. It is described the modern and the most frequently used methods and diagnostic systems (neuropsychological diagnostics battery), which allow determine the character of the strengths and weaknesses of individual cognitive functioning, which determines the efficiency of daily activity. The article presented descriptions of the composition of such batteries, guidelines for use. Separately, it is described the requirements for the study of neurocognitive status in patients with human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) and the principles of study