Design and Implementation of a Remote Care Application Based on Microservice Architecture

Microservice Architecture (MSA) is an architectural style for service-based software systems. MSA puts a strong emphasis on high cohesion and loose coupling of the services that provide systems' functionalities. As a result of this, MSA-based software architectures exhibit increased scalability and extensibility, and facilitate the application of continuous integration techniques. This paper presents a case study of an MSA-based Remote Care Application (RCA) that allows caregivers to remotely access smart home devices. The goal of the RCA is to assist persons being cared in Activities of Daily Living. Employing MSA for the realization of the RCA yielded several lessons learned, e.g., (i) direct transferability of domain models based on Domain-driven Design; (ii) more efficient integration of features; (iii) speedup of feature delivery due to MSA facilitating automated deployment.Comment: 8 pages, 3 figures, 2 table

Book review: Places of Nature in Ecologies of Urbanism Anne Rademacher and K Sivaramakrishnan (eds) . Hong Kong University Press, Hong Kong, 2017.

Places of Nature in Ecologies of Urbanism Anne Rademacher and K Sivaramakrishnan (eds) . Hong Kong University Press, Hong Kong, 2017, pp. xi +255 (ISBN 978-988-8930-60-1)

MRL voor oxaalzuur in honing

Oxaalzuur is onmisbaar voor de late herfst-/winterfase in de geïntegreerde bestrijding van de varroamijt (Varroa destructor). Daarom heeft de Europese Werkgroep voor Varroabestrijding een procedure opgestart bij de EMEA (EU Agentschap voor Evaluatie van Medische Producten) voor toelating van oxaalzuur als veterinair medicament. Onderdeel van de procedure was de opstelling van een MRL-dossier (Maximum Residu Level) over de toxiciteit van oxaalzuur en de mogelijke residuvorming in honing. Het resultaat van een en ander is dat oxaalzuur nu toegepast kan worden zonder dat een maximumgrens gesteld is voor residuen in honin

Riemann solvers and undercompressive shocks of convex FPU chains

We consider FPU-type atomic chains with general convex potentials. The naive continuum limit in the hyperbolic space-time scaling is the p-system of mass and momentum conservation. We systematically compare Riemann solutions to the p-system with numerical solutions to discrete Riemann problems in FPU chains, and argue that the latter can be described by modified p-system Riemann solvers. We allow the flux to have a turning point, and observe a third type of elementary wave (conservative shocks) in the atomistic simulations. These waves are heteroclinic travelling waves and correspond to non-classical, undercompressive shocks of the p-system. We analyse such shocks for fluxes with one or more turning points. Depending on the convexity properties of the flux we propose FPU-Riemann solvers. Our numerical simulations confirm that Lax-shocks are replaced by so called dispersive shocks. For convex-concave flux we provide numerical evidence that convex FPU chains follow the p-system in generating conservative shocks that are supersonic. For concave-convex flux, however, the conservative shocks of the p-system are subsonic and do not appear in FPU-Riemann solutions

Automated glycan assembly of ¹⁹F labelled glycan probes enables high‐throughput NMR studies of protein‐glycan interactions

Protein‐glycan interactions mediate important biological processes, including pathogen host invasion and cellular communication. Major challenges to monitoring these low affinity interactions are the required high sensitivity of a biophysical assay and to cover a breath of synthetic well‐defined structures. Here, we showcase an expedite approach that integrates automated glycan assembly (AGA) of 19 F labelled probes and high‐throughput NMR methods, enabling the study of protein‐glycan interactions. Synthetic Lewis type 2 antigens were screened against seven glycan binding proteins (GBPs), including DC‐SIGN and BambL, respectively involved in HIV‐1 and lung infections in immunocompromised patients, confirming the preference for fucosylated glycans (Le x , H type 2, Le y ). Previously unknown glycan‐lectin weak interactions were detected, and thermodynamic data were obtained. Enzymatic reactions were monitored in real‐time, delivering kinetic parameters. These results demonstrate the utility of AGA combined with 19 F NMR for the discovery and characterization of glycan‐protein interactions, opening up new perspectives for 19 F labelled complex glycans

Level density of a Fermi gas: average growth and fluctuations

We compute the level density of a two--component Fermi gas as a function of the number of particles, angular momentum and excitation energy. The result includes smooth low--energy corrections to the leading Bethe term (connected to a generalization of the partition problem and Hardy--Ramanujan formula) plus oscillatory corrections that describe shell effects. When applied to nuclear level densities, the theory provides a unified formulation valid from low--lying states up to levels entering the continuum. The comparison with experimental data from neutron resonances gives excellent results.Comment: 4 pages, 1 figur

Закономерности изменения коэффициента динамичности в линии привода прокатной клети в процессе её работы

Показано, что процессе работы клети коэффициент динамичности на шпиндельном и моторном участках периодически существенно изменяется за счет износа сочленяемых элементов и развития зазоров. Установленные закономерности позволяют прогнозировать максимальные динамические нагрузки в линии привода

Quantum Invariants, Modular Forms, and Lattice Points II

We study the SU(2) Witten--Reshetikhin--Turaev invariant for the Seifert fibered homology spheres with M-exceptional fibers. We show that the WRT invariant can be written in terms of (differential of) the Eichler integrals of modular forms with weight 1/2 and 3/2. By use of nearly modular property of the Eichler integrals we shall obtain asymptotic expansions of the WRT invariant in the large-N limit. We further reveal that the number of the gauge equivalent classes of flat connections, which dominate the asymptotics of the WRT invariant in N ->\infinity, is related to the number of integral lattice points inside the M-dimensional tetrahedron