Rapid macular hole formation, spontaneous closure, and reopening after pars plana vitrectomy for macula-sparing retinal detachment

PURPOSE: To report a single case of macular hole opening, spontaneous closure, and reopening in the three month period after pars plana vitrectomy for rhegmatogenous retinal detachment METHODS: Case report PATIENT: A 59-year-old man with a macula-sparing rhegmatogenous retinal detachment who underwent uncomplicated pars plana vitrectomy with gas tamponade RESULTS: The patient developed a full-thickness macular hole two months post-operatively. The hole was noted to spontaneously close three months post-operatively, but then reopened four months post-operatively and required repeat pars plana vitrectomy and inner limiting membrane peel for definitive closure. The rapidity with which the macular hole developed after pars plana vitrectomy for macula-sparing rhegmatogenous retinal detachment and its dynamic behavior have not been previously reported. CONCLUSIONS: Full-thickness macular holes may rarely develop rapidly, spontaneous close, and reopen after pars plana vitrectomy for rhegmatogenous retinal detachment, even in macula-sparing cases

Correlation between baseline echographic features of endophthalmitis, microbiological isolates, and visual outcomes

The purpose of this study was to examine the baseline echographic features in culture-positive and culture-negative endophthalmitis and to correlate these echographic features with final visual outcomes. We identified a retrospective noncomparative case series of patients with a clinical diagnosis of endophthalmitis and a baseline echographic examination between 1996 and 2010 at a single institution. Graded echographic features studied included: dense, moderate, and mild vitreous opacities; marked, moderate, and mild vitreous membranes; retinal detachment; and choroidal detachment. These were compared between culture-negative, coagulase-negative staphylococci, and other culture-positive cases of endophthalmitis, and were correlated with final visual outcomes. Of 149 patients reviewed, 60 were culture-negative, 26 grew coagulase-negative staphylococci, and 60 grew other culture-positive species. Three had multiple culture isolates. The presence of dense, moderate, and mild vitreous opacities, marked, moderate, and mild vitreous membranes, retinal detachment, and choroidal detachment was not significantly different between the three groups (P = 0.86, P = 0.56, P = 0.34, P = 0.45, respectively). The presence of advanced echographic features of dense vitreous opacities, marked vitreous membranes, retinal detachment, and choroidal detachment was correlated with poorer visual acuity outcomes (P = 0.005, P = 0.0001, P < 0.0001, and P < 0.0001, respectively). No correlation could be made between echographic features and the organism. The presence of advanced echographic features, such as dense vitreous opacities, marked vitreous membranes, retinal detachment, and choroidal detachment, was correlated with worse visual outcomes

Prophylactic Scleral Buckle Implantation in Knobloch Syndrome

Knobloch syndrome is a rare autosomal recessive disorder characterized by a triad of high myopia, vitreoretinal degeneration, and congenital occipital scalp defects. On literature review of all reported cases, 25 of 85 eyes (29%) of patients diagnosed as having Knobloch syndrome have suffered retinal detachment. Due to high myopia, surgical repair of the retinal detachment is challenging and patients frequently require several reoperations. Even after vitrectomy or scleral buckle for retinal detachment, the final visual acuity outcomes are poor, with 11 of 12 (92%) patients having 20/ 200 visual acuity or worse and 6 of 12 (50%) having counting fingers visual acuity or worse. The role of retinal detachment prophylaxis has been discussed for other vitreoretinal degeneration disorders, but not for this disease. The authors report the case of a child affected with Knobloch syndrome who presented with total retinal detachment in the left eye at 24 months of age. He underwent successful repair and was then treated with prophylactic scleral buckle implantation in the right eye 5 months later. The retina in both of his eyes remains attached 4 years later

A 10-Year Study of Membrane Filter System Versus Blood Culture Bottles in Culturing Vitrectomy Cassette Vitreous in Infectious Endophthalmitis

To compare the microbiological outcomes of membrane filter system and blood culture bottle techniques in culturing diluted vitrectomy cassette vitreous. Retrospective comparative case series. Diluted vitrectomy cassette vitreous specimens from March 25, 2002 to July 11, 2012 were cultured using both membrane filter system and blood culture bottles. The isolates were divided into 3 groups: ones that had positive cultures with (1) both membrane filter system and blood culture bottles, (2) membrane filter system only, and (3) blood culture bottles only. The 48-hour as well as 2-week results were documented. A total of 447 patients with 168 positive cultures were studied. At the 48-hour time point, 126 isolates were documented. Of those, 104 (82%) were culture positive with both membrane filter system and blood culture bottles, 15 (12%) were culture positive only with membrane filter system, and 7 (6%) were culture positive only with blood culture bottles. At the 2-week time point, an additional 42 organisms were isolated. Of those, 19 (45%) were culture positive with both membrane filter system and blood culture bottles, 11 (26%) with membrane filter system only, and 12 (29%) with blood culture bottles only. Out of 168 total isolates, 123 (73%) were culture positive with both membrane filter system and blood culture bottles, 26 (16%) with membrane filter system only, and 19 (11%) with blood culture bottles only. Among all microbiological outcomes, there was no significant difference between membrane filter system and blood culture bottle (P = .37). Of those organisms that were culture positive only with either membrane filter system or blood culture bottle, mold and Mycobacterium species were culture positive more commonly with membrane filter system (P = .034 and P = .016, respectively), and gram-positive organisms were culture positive more commonly with blood culture bottles (P = .021). In the current study, a combination of membrane filter system and blood culture bottles for culture of diluted vitrectomy cassette vitreous provides the highest number of positive culture outcomes. The blood culture bottle method is technically easier and represents a viable alternative to the more complex membrane filter system technique

The Spectrum of Pediatric Orbital BB Gun Injuries: A Case Series

Three cases of pediatric BB orbital injury are reported demonstrating varying outcomes. Pediatric orbital BB injuries have a wide spectrum of clinical outcomes depending on the ocular structures involved. Improved safety education of patients and parents is necessary to reduce the burden of these vision-threatening injuries

An unusual ophthalmic finding in Lane-Hamilton syndrome

Lane-Hamilton syndrome is a rare condition that is characterized by idiopathic pulmonary hemosiderosis and celiac disease. We report the case of an 18-month-old girl with Lane-Hamilton syndrome who had unilateral pigmentary retinopathy