Kaposi’s Sarcoma Presenting As Lymphadenopathy In An Immunocompetent Patient

Introduction: Kaposi’s sarcoma (KS) is an angioproliferative disorder first described in 1872 by Moritz Kaposi. Four main clinical presentations of KS have been described: classic, endemic, iatrogenic and epidemic. KS involvement of the lymph nodes is extremely uncommon in the classical variant form, especially if it precedes the skin manifestations. We describe the case of an elderly HIV-negative patient presenting with lymphadenopathy who was found to have KS. Case Report: A 67-year-old patient was admitted for exploration of polyadenopathies in the context of a general decline in health. Physical examination revealed an erythematosus left lower limb rash associated with angiomatous nodules and multiple lymphadenopathies. The diagnosis of erysipelas in the left leg was retained and the patient was treated with good evolution of the rash but persistence of the angiomatous nodules and the polyadenopathies. Skin and lymph node biopsies led to a diagnosis of KS. The patient is proposed for polychemotherapy. Conclusion: KS must be suspected in lymphadenopathies despite the absence of typical cutaneous signs of the disease and in immunocompetent patients

Cutaneous vasculitis associated with Helicobacter pylori

Helicobacter pylori is a widely prevalent microbe, Epidemiological and experimental data pointed recently to a strong relation of H. pylori infection on the development of many extragastric diseases, including several allergic and autoimmune diseases. We report a 65-year-old man who presented with cutaneous vasculitis accompanied by gastric H. pylori (Hp) infection. The gastro intestinal manifestations and purpuric lesions were dramatically resolved after Hp eradication therapy

Bowen’s disease in a patient with Primary Sjögren’s syndrome: A case report and a review of the literature

A rare case of Bowen’s disease (BD) in a patient with Primary Sjögren’s syndrome is reported. A 42-year-old woman suffering from Primary Sjögren’s syndrome retained on the basis of clinical and serological findings, was admitted 3 years later for genital bleeding. The diagnosis of Bowen’s disease was established by clinical and histolopathological examination. Classical association of lymphoma and Sjögren’s syndrome is described, but to the best of our knowledge, it is the second report of BD associated to Sjögren’s syndrome in published literature. A common physio-pathological etiology cannot be excluded

Lupus erythematosus panniculitis: A case report

Lupus erythematosus panniculitis (LEP), an uncommon variant in the clinicopathological spectrum of lupus erythematosus (LE), is rare. There are only a few reported series of patients with this condition; none in individuals of North African ancestry. LEP is characterized by inflammation of the deep dermis and subcutaneous tissue. It usually consists of nodules and hardened subcutaneous plaques on the forehead, cheeks, proximal extremities, and buttocks. Leg involvement is rare and can lead to misdiagnosis. A case of LEP, with unusual involvement of legs, is reported in a 40-year-old woman who had the diagnosis of systemic lupus erythematosus (SLE) four years ago