Prognostic stratification of adult primary glioblastoma multiforme patients based on their tumor gene amplification profiles

Several classification systems have been proposed to address genomic heterogeneity of glioblastoma multiforme, but they either showed limited prognostic value and/or are difficult to implement in routine diagnostics. Here we propose a prognostic stratification model for these primary tumors based on tumor gene amplification profiles, that might be easily implemented in routine diagnostics, and potentially improve the patients management. Gene amplification profiles were prospectively evaluated in 80 primary glioblastoma multiforme tumors using singlenucleotide polymorphism arrays and the results obtained validated in publicly available data from 267/347 cases. Gene amplification was detected in 45% of pati

Flutuações sazonais na abundância de Phalacrocorax brasilianus (Gmelin) no estuário do Saco da Fazenda, Itajaí, Santa Catarina, Brasil Seasonal changes in the abundance of Phalacrocorax brasilianus (Gmelin) in the estuary of Saco da Fazenda, Itajaí, Santa Catarina, Brazil

<abstract language="eng">The Neotropic cormorant is one of the most comm on estuarine birds along SantaCatarina's shore, especially in artisanal fishery areas, where it obtains food easily. During the period from January, 1996 to December, 1999, and of January to December, 2001, the cormorants were monitored monthly in the estuary. The population P. brasilianus (Gmelin, 1789) presented seasonal changes with the same annual pattern of increment of the abundance. Significant differences were recorded between the seasons and the medium abundance of birds. Those differences can be attributed to the events of the life cicle of the species and the oscillations in the estuary water temperature

Ocorrência e abundância de Rynchops niger Linnaeus, no litoral de Santa Catarina, Brasil Occurrence and abundance of Rynchops niger Linnaeus in the coast of Santa Catarina, Brazil

O talha-mar Rynchops niger Linnaeus, 1758 habita os grandes rios, lagos e regiões costeiras durante as migrações, na América do Sul e do Norte. Esse trabalho tem por objetivo disponibilizar informações básicas sobre a ocorrência e abundância de talha-mar no litoral de Santa Catarina. Durante o período de abril/2002 a maio/2003 foram realizados censos sazonais (trimestrais) e mensais em Itajaí, com auxílio de binóculos 10 x 50. O talha-mar é mais freqüente no aterro da Baía Sul (Florianópolis), no verão e outono, na primavera-verão em São José e Tijucas e no outono-inverno no estuário do Saco da Fazenda (Itajaí). Neste estuário, a população apresentou flutuações acentuadas ao longo do ano, com as maiores abundâncias ocorrendo em agosto/2001, janeiro/2002 e março/2003.<br>The black skimmer inhabits the great rivers, lakes and coastal areas during the migrations, in South and North America. This work aims to make available basic information about the occurrence and abundance of the black skimmer in the coast of Santa Catarina. From April/2002 to May/2003 seasonal censuses were accomplished, and monthly in Itajaí, with aid of binoculars 10 x 50. The black skimmer is more frequent in the embankment of the South Bay (Florianópolis), in the summer and autumn, in the spring-summer in São José and Tijucas and in the autumn-winter in the estuary of the Saco da Fazenda (Itajaí). In this estuary, the population presented accentuated flotation along the year, with the largest abundances happening in August/2001, January/2002 and March/2003