4,279 research outputs found
A model-based approach to recovering the structure of a plant from images
We present a method for recovering the structure of a plant directly from a
small set of widely-spaced images. Structure recovery is more complex than
shape estimation, but the resulting structure estimate is more closely related
to phenotype than is a 3D geometric model. The method we propose is applicable
to a wide variety of plants, but is demonstrated on wheat. Wheat is made up of
thin elements with few identifiable features, making it difficult to analyse
using standard feature matching techniques. Our method instead analyses the
structure of plants using only their silhouettes. We employ a generate-and-test
method, using a database of manually modelled leaves and a model for their
composition to synthesise plausible plant structures which are evaluated
against the images. The method is capable of efficiently recovering accurate
estimates of plant structure in a wide variety of imaging scenarios, with no
manual intervention
Lorentz-Violating Supergravity
The standard forms of supersymmetry and supergravity are inextricably wedded
to Lorentz invariance. Here a Lorentz-violating form of supergravity is
proposed. The superpartners have exotic properties that are not possible in a
theory with exact Lorentz symmetry and microcausality. For example, the bosonic
sfermions have spin 1/2 and the fermionic gauginos have spin 1. The theory is
based on a phenomenological action that is shown to follow from a simple
microscopic and statistical picture.Comment: 15 pages; to be published in Proceedings of Beyond the Desert 2003
(Castle Ringberg, Tegernsee, Germany, 9-14 June 2003), edited by H. V.
Klapdor-Kleingrothau
Forward-backward Asymmetry and Branching Ratio of B \rar K_1 \ell^+ \ell^- Transition in Supersymmetric Models
The mass eigen states and are mixture of the strange
members of two axial-vector SU(3) octet, and .
Taking into account this mixture, the forward-backward asymmetry and branching
ratio of B \rar K_1(1270,1400) \ell^+ \ell^- transitions are studied in the
framework of different supersymmetric models. It is found that the results have
considerable deviation from the standard model predictions. Any measurement of
these physical observables and their comparison with the results obtained in
this paper can give useful information about the nature of interactions beyond
the standard model.Comment: 14 pages, 4 figure
Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-ÎșB by targeting p65.
Human bocavirus (HBoV), a parvovirus, is a single-stranded DNA etiologic agent causing lower respiratory tract infections in young children worldwide. Nuclear factor kappa B (NF-ÎșB) transcription factors play crucial roles in clearance of invading viruses through activation of many physiological processes. Previous investigation showed that HBoV infection could significantly upregulate the level of TNF-α which is a strong NF-ÎșB stimulator. Here we investigated whether HBoV proteins modulate TNF-α-mediated activation of the NF-ÎșB signaling pathway. We showed that HBoV NS1 and NS1-70 proteins blocked NF-ÎșB activation in response to TNF-α. Overexpression of TNF receptor-associated factor 2 (TRAF2)-, IÎșB kinase alpha (IKKα)-, IÎșB kinase beta (IKKÎČ)-, constitutively active mutant of IKKÎČ (IKKÎČ SS/EE)-, or p65-induced NF-ÎșB activation was inhibited by NS1 and NS1-70. Furthermore, NS1 and NS1-70 didn't interfere with TNF-α-mediated IÎșBα phosphorylation and degradation, nor p65 nuclear translocation. Coimmunoprecipitation assays confirmed the interaction of both NS1 and NS1-70 with p65. Of note, NS1 but not NS1-70 inhibited TNF-α-mediated p65 phosphorylation at ser536. Our findings together indicate that HBoV NS1 and NS1-70 inhibit NF-ÎșB activation. This is the first time that HBoV has been shown to inhibit NF-ÎșB activation, revealing a potential immune-evasion mechanism that is likely important for HBoV pathogenesis
Trends for nanotechnology development in China, Russia, and India
China, Russia, and India are playing an increasingly important role in global nanotechnology research and development (R&D). This paper comparatively inspects the paper and patent publications by these three countries in the Thomson Science Citation Index Expanded (SCI) database and United States Patent and Trademark Office (USPTO) database (1976â2007). Bibliographic, content map, and citation network analyses are used to evaluate country productivity, dominant research topics, and knowledge diffusion patterns. Significant and consistent growth in nanotechnology papers are noted in the three countries. Between 2000 and 2007, the average annual growth rate was 31.43% in China, 11.88% in Russia, and 33.51% in India. During the same time, the growth patterns were less consistent in patent publications: the corresponding average rates are 31.13, 10.41, and 5.96%. The three countriesâ paper impact measured by the average number of citations has been lower than the world average. However, from 2000 to 2007, it experienced rapid increases of about 12.8 times in China, 8 times in India, and 1.6 times in Russia. The Chinese Academy of Sciences (CAS), the Russian Academy of Sciences (RAS), and the Indian Institutes of Technology (IIT) were the most productive institutions in paper publication, with 12,334, 6,773, and 1,831 papers, respectively. The three countries emphasized some common research topics such as âQuantum dots,â âCarbon nanotubes,â âAtomic force microscopy,â and âScanning electron microscopy,â while Russia and India reported more research on nano-devices as compared with China. CAS, RAS, and IIT played key roles in the respective domestic knowledge diffusion
Joint PDF modelling of turbulent flow and dispersion in an urban street canyon
The joint probability density function (PDF) of turbulent velocity and
concentration of a passive scalar in an urban street canyon is computed using a
newly developed particle-in-cell Monte Carlo method. Compared to moment
closures, the PDF methodology provides the full one-point one-time PDF of the
underlying fields containing all higher moments and correlations. The
small-scale mixing of the scalar released from a concentrated source at the
street level is modelled by the interaction by exchange with the conditional
mean (IECM) model, with a micro-mixing time scale designed for geometrically
complex settings. The boundary layer along no-slip walls (building sides and
tops) is fully resolved using an elliptic relaxation technique, which captures
the high anisotropy and inhomogeneity of the Reynolds stress tensor in these
regions. A less computationally intensive technique based on wall functions to
represent boundary layers and its effect on the solution are also explored. The
calculated statistics are compared to experimental data and large-eddy
simulation. The present work can be considered as the first example of
computation of the full joint PDF of velocity and a transported passive scalar
in an urban setting. The methodology proves successful in providing high level
statistical information on the turbulence and pollutant concentration fields in
complex urban scenarios.Comment: Accepted in Boundary-Layer Meteorology, Feb. 19, 200
The cytochrome p450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease
Fatty liver disease is an emerging public health problem without effective therapies, and chronic hepatic inflammation is a key pathologic mediator in its progression. Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which have potent anti-inflammatory effects. Although promoting the effects of EETs elicits anti-inflammatory and protective effects in the cardiovascular system, the contribution of CYP-derived EETs to the regulation of fatty liver disease-associated inflammation and injury is unknown. Using the atherogenic diet model of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH), our studies demonstrated that induction of fatty liver disease significantly and preferentially suppresses hepatic CYP epoxygenase expression and activity, and both hepatic and circulating levels of EETs in mice. Furthermore, mice with targeted disruption of Ephx2 (the gene encoding soluble epoxide hydrolase) exhibited restored hepatic and circulating EET levels and a significantly attenuated induction of hepatic inflammation and injury. Collectively, these data suggest that suppression of hepatic CYP-mediated EET biosynthesis is an important pathological consequence of fatty liver disease-associated inflammation, and that the CYP epoxygenase pathway is a central regulator of the hepatic inflammatory response in NAFLD/NASH. Future studies investigating the utility of therapeutic strategies that promote the effects of CYP-derived EETs in NAFLD/NASH are warranted
Phonon-assisted radiofrequency absorption by gold nanoparticles resulting in hyperthermia
It is suggested that in gold nanoparticles (GNPs) of about 5 nm sizes used in
the radiofrequency (RF) hyperthermia, an absorption of the RF photon by the
Fermi electron occurs with involvement of the longitudinal acoustic vibrational
mode (LAVM), the dominating one in the distribution of vibrational density of
states (VDOS). This physical mechanism helps to explain two observed phenomena:
the size dependence of the heating rate (HR) in GNPs and reduced heat
production in aggregated GNPs. The argumentation proceeds within the
one-electron approximation, taking into account the discretenesses of energies
and momenta of both electrons and LAVMs. The heating of GNPs is thought to
consist of two consecutive processes: first, the Fermi electron absorbs
simultaneously the RF photon and the LAVM available in the GNP; hereafter the
excited electron gets relaxed within the GNP's boundary, exciting a LAVM with
the energy higher than that of the previously absorbed LAVM. GNPs containing
the Ta and/or Fe impurities are proposed for the RF hyperthermia as promising
heaters with enhanced HRs, and GNPs with rare-earth impurity atoms are also
brought into consideration. It is shown why the maximum HR values should be
expected in GNPs with about 5-7 nm size.Comment: proceedings at the NATO Advanced Research workshop FANEM-2015 (Minsk,
May 25-27, 2015). To be published in the final form in: "Fundamental and
Applied NanoElectroMagnetics" (Springer Science + Business Media B.V.
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