26 research outputs found
Reduced thrombus formation in native blood of homozygous factor VII- deficient patients at high arterial wall shear rate
No full textReduced thrombus formation in native blood of homozygous factor VII- deficient patients at high arterial wall shear rate
No full textTHE PAPWORTH PLUG – successful use of high dose fibrinogen concentrate and platelet concentrate in potential life-threatening complication after cardiopulmonary bypass surgery in a patient with Type 2M Vicenza von Willebrand Disease
No full textERK2 activation in arteriolar and venular murine thrombosis: platelet receptor GPIb vs. P2X.
Full text linkThe functional significance of extracellular signal-regulated kinase 2 (ERK2) activation was investigated during shear induced human platelet aggregation (SIPA) in vitro and during shear controlled thrombosis in vivo in intestinal arterioles and venules of wild type (WT) and transgenic (TG) mice with platelet-specific overexpression of human P2X(1) (TG). The conclusions are that P2X(1) and ERK2 both participate in shear stress controlled thrombosis, but ERK2 activation is initiated predominantly via GPIb-VWF interactions
The effects on coagulation of the reinfusion of unprocessed residual blood from the cardiopulmonary bypass
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