6 research outputs found

    O cultivo da videira: informações básicas.

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    bitstream/item/87140/1/o-cultivo.pdfEsta publicação tem dois exemplares editados em anos diferentes:m 1984 e 1996

    O-[2-Hydroxy-3-(dialkylamino)propyl]ethers of (+)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one oxime (camphor oxime) with analgesic and antiarrhythmic activities

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    A novel series of O-[2-hydroxy-3-(dialkylamino)propyl]ethers of (+)-camphor oxime was prepd. and tested for its cardiovascular, analgesic and anti-inflammatory properties. No significant anti-inflammatory and hypotensive activities were displayed by any of the compds., whereas several of them are reasonably active as antiarrhythmic and analgesic agents

    N-Acyl-N-phenyl ureas of piperidine and substituted piperidines endowed with antiinflammatory and antiproliferative activities

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    Six series of N-acyl-N-Ph ureas of piperidine, and 2-ethyl-, 3-methyl-, 4-methyl-, 4-phenyl-, cis-2,6-dimethylpiperidine were synthesized and evaluated for their anti-inflammatory, anesthetic, anti-pyretic properties. Some derivs. were also assayed for anti-proliferative activity. Several compds. showed an anti-inflammatory activity comparable or slightly inferior to that of indomethacin in rats. All the compds. were devoid of anti-pyretic activity and only a few of them exhibited a low level of infiltration anesthesia in mice. One compd. (I) showed a broad spectrum anti-cancer activity (at low micromolar concns.), particularly significant against leukemia subpanel

    N-Substituted 3-(arylamino)-4,5-dihydro-2H-benz[g]indazol-2-yl acetamides with antiinflammatory and analgesic activities

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    Title compds. I (NR2 = NHCHMe2, NHCH2CH2OEt, NHCH2Ph, morpholino; X = H, Cl, Br) were prepd. and tested in comparison with previously studied analogs. I showed only weak antiarrhythmic properties but good antiinflammatory and antinociceptive activity, particularly evident in the morpholino deriv
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