Zeta-management: categorical and fractional differential approaches

The aim of this note is to introduce and justify the reasons why the traditional differential approach of complex systems, and more specifically non-additive systems, must be recognized as an epistemological failure (e.g. in economy, finance or limited in social agent models). The categorical character of the context proper to any type of irreversible exchange is analyzed. This approach underlines and explains the weaknesses of the set theory generally utilized. Beyond the mathematical concepts their application in project management provides an illustrative example allowing an easy understanding of the statements of problems attached to non-additive and irreversible complex system. We will see why it is necessary to shift the analysis from the set theory toward the theory of categories and why this choice very naturally introduces the use of non- integer order Differential Equations

LSST: from Science Drivers to Reference Design and Anticipated Data Products

(Abridged) We describe here the most ambitious survey currently planned in the optical, the Large Synoptic Survey Telescope (LSST). A vast array of science will be enabled by a single wide-deep-fast sky survey, and LSST will have unique survey capability in the faint time domain. The LSST design is driven by four main science themes: probing dark energy and dark matter, taking an inventory of the Solar System, exploring the transient optical sky, and mapping the Milky Way. LSST will be a wide-field ground-based system sited at Cerro Pach\'{o}n in northern Chile. The telescope will have an 8.4 m (6.5 m effective) primary mirror, a 9.6 deg$^2$ field of view, and a 3.2 Gigapixel camera. The standard observing sequence will consist of pairs of 15-second exposures in a given field, with two such visits in each pointing in a given night. With these repeats, the LSST system is capable of imaging about 10,000 square degrees of sky in a single filter in three nights. The typical 5$\sigma$ point-source depth in a single visit in $r$ will be $\sim 24.5$ (AB). The project is in the construction phase and will begin regular survey operations by 2022. The survey area will be contained within 30,000 deg$^2$ with $\delta<+34.5^\circ$, and will be imaged multiple times in six bands, $ugrizy$, covering the wavelength range 320--1050 nm. About 90\% of the observing time will be devoted to a deep-wide-fast survey mode which will uniformly observe a 18,000 deg$^2$ region about 800 times (summed over all six bands) during the anticipated 10 years of operations, and yield a coadded map to $r\sim27.5$. The remaining 10\% of the observing time will be allocated to projects such as a Very Deep and Fast time domain survey. The goal is to make LSST data products, including a relational database of about 32 trillion observations of 40 billion objects, available to the public and scientists around the world.Comment: 57 pages, 32 color figures, version with high-resolution figures available from https://www.lsst.org/overvie

La ménopause et son traitement hormonal substitutif en 2003 (enquête auprès des médecins généralistes de Charente)

POITIERS-BU Médecine pharmacie (861942103) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Les biotechnologies (la planche de salut de l'industrie pharmaceutique ?)

Dans les années 1980, la naissance de la biotechnologie a bouleversé l'industrie du médicament. L'industrie des biotechnologies (biotech) a apporté une rupture dans le modèle d'innovation et dans les technologies utilisées. Aujourd'hui, la reconfiguration qui s'opère dans l'industrie pharmaceutique est fortement influencée par ce bouleversement. Ce que certains appellent le virage biotech devient une nécessité croissante pour les laboratoires pharmaceutiques. Dans le but de comprendre ces nouveaux enjeux, nous réalisons une revue historique de l'émergence de l'industrie biotech et du développement de l'industrie pharmaceutique. Nous étudions ainsi ce qui distingue ces deux industries. Dans un deuxième temps, nous montrons comment l'industrie classique des Big Pharma intègre progressivement le modèle biotech poussée par le déclin de son modèle traditionnel. Cette analyse nous permet de décrypter les évolutions actuelles dans l'industrie du médicament et de définir les facteurs clés de succès du développement des traitements innovants de demain, qui tiennent à la fois au progrès scientifique dans les sciences de la vie et à des transformations dans l'organisation de la recherche et du développement des médicaments. Enfin sous cet éclairage et à titre d'exemple, nous analysons la stratégie du groupe Sanofi et le rachat récent de la société de biotechnologies GenzymeLYON1-BU Santé (693882101) / SudocSudocFranceF

Rethinking Entrepreneurship : debating research orientations

International audienceEntrepreneurship is a growing field of research, attracting researchers from many different disciplines including economics, sociology, psychology, and management. The concept of entrepreneurship, and research in the field, is becoming institutionalized, increasingly oriented by influential trends, theories and methods, following the mainstream and being shaped accordingly. The objective of this book is to move beyond mainstream approaches and assumptions which are dominating the field, and to raise questions about the nature and process of entrepreneurship research. Over twelve chapters, leading international thinkers in the field debate the impact and the consequences of institutionalization. Taking key research orientations including multidisciplinarity, international entrepreneurship, social entrepreneurship, and ethics, it takes a critical and constructive and sometimes controversial posture and encourages a re-examination of the way we look at the social and economic phenomenon of entrepreneurship. This book is vital reading for entrepreneurship researchers and educators, advanced students and policy-makers in Entrepreneurship, Economics, Sociology and Psychology.<br/

Le suivi des femmes enceintes en Charente (proposition de réseau Médecins généralistes-Obstétriciens)

POITIERS-BU Médecine pharmacie (861942103) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Phenomenological approaches to work, life and responsibility

International audienceThis paper serves two purposes. It is an introduction to the theme of this issue of Society and Business Review which is devoted to "Phenomenological approaches to work, life and responsibility" as well as a presentation of the authors' various contributions. The authors of this paper share the sentiment that management sciences and practices may drive people in a way such that the sense of life has been altered and people, contrary to Kant's definition of moral behavior, are treated as means instead of ends. Moreover, starting from a widely-spread malaise in modern organizations, they argue how phenomenology can provide an approach that can be helpful in assessing one's present situation as well as getting a renewed perception concerning work and life. The authors demonstrate the relevance of Husserl's phenomenology in criticizing management techniques for they direct us to objectives that are abstract, calculable, not one's own, and distant. They single out Husserl's concept of epoche for its high relevance with the theme of this issue and its different papers. The findings suggest Husserl's concept of epoche (suspension) can be considered as the starting point of a process allowing us to firstly take distance with our usual taken for granted assumptions regarding life and work (bracketing) and then to re-establish a genuine connection with Husserl's "world of life".<br/

Rethinking Entrepreneurship : debating research orientations

International audienceEntrepreneurship is a growing field of research, attracting researchers from many different disciplines including economics, sociology, psychology, and management. The concept of entrepreneurship, and research in the field, is becoming institutionalized, increasingly oriented by influential trends, theories and methods, following the mainstream and being shaped accordingly. The objective of this book is to move beyond mainstream approaches and assumptions which are dominating the field, and to raise questions about the nature and process of entrepreneurship research. Over twelve chapters, leading international thinkers in the field debate the impact and the consequences of institutionalization. Taking key research orientations including multidisciplinarity, international entrepreneurship, social entrepreneurship, and ethics, it takes a critical and constructive and sometimes controversial posture and encourages a re-examination of the way we look at the social and economic phenomenon of entrepreneurship. This book is vital reading for entrepreneurship researchers and educators, advanced students and policy-makers in Entrepreneurship, Economics, Sociology and Psychology.<br/

(Re)penser la rébellion des cadres : actes de la journée du 15 Décembre 2006 organisée par le centre de recherche OCE/EMLYON à EMLYON

International audienc

Remontée de fontis au-dessus des cavités souterraines - utilisation d'un géosynthétique bi-raideur instrumenté

National audienc