55 research outputs found
Carotid Baroreflex Activation: Past, Present, and Future
Electrical activation of the carotid baroreceptor system is an attractive therapy for the treatment of resistant hypertension. In the past, several attempts were made to directly activate the baroreceptor system in humans, but the method had to be restricted to a few selected patients. Adverse effects, the need for better electrical devices and better surgical techniques, and the lack of knowledge about long-term effects has greatly hampered developments in this area for many years. Recently, a new and promising device was evaluated in a multicenter feasibility trial, which showed a clinically and statistically significant reduction in office systolic blood pressure (>20Â mm Hg). This reduction could be sustained for at least 2Â years with an acceptable safety profile. In the future, this new device may stimulate further application of electrical activation of the carotid baroreflex in treatment-resistant hypertension
How Many Scientists Fabricate and Falsify Research? A Systematic Review and Meta-Analysis of Survey Data
The frequency with which scientists fabricate and falsify data, or commit other forms of scientific misconduct is a matter of controversy. Many surveys have asked scientists directly whether they have committed or know of a colleague who committed research misconduct, but their results appeared difficult to compare and synthesize. This is the first meta-analysis of these surveys
Biological effects of exposure to static electric fields in humans and vertebrates: a systematic review
Intraoperative Echocardiography and Doppler Color Flow Mapping in Freehand Allograft Aortic Valve and Root Replacement
The potential of an online educational platform to contribute to achieving sustainable development goals: a mixed-methods evaluation of the Peoples-uni online platform
Examining Interactions Between and Among Predictors of Net Ecosystem Exchange: A Machine Learning Approach in a Semi-arid Landscape
Estimation of the configurational heat capacity of polyisobutylene, isobutane and 2,2,4-isomethylpentane above the glass transition temperature
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