Towards a Psychologically Plausible Dynamic Binding Mechanism

A psychologically plausible binding mechanism for connectionist networks is sought. Twenty--two subjects were tachistoscopically presented with pairs of coloured shapes which they had to identify almost immediately. The frequencies of their correct responses and various types of incorrect responses were recorded. Simulations of connectionist binding mechanisms were undertaken to discover whether the experimental results can be accounted for by either an enumerated representation model, a non--concatenatively compositional representation model or an oscillatory representation model employing phase synchrony to indicate binding. The effects on these simulations of the different values of their free variables was explored. Whilst none of the simulation results matched the experimental results, the detailed findings suggest improvements to both the experimental method and the design of the simulations. 1. INTRODUCTION The dynamic binding problem has become a important theoretical and pract..

Medium-throughput production of recombinant human proteins: protein production in insect cells.

This chapter describes the step-by-step methods employed by the Structural Genomics Consortium (SGC) for screening and producing proteins in the baculovirus expression vector system (BEVS). This eukaryotic expression system was selected and a screening process established in 2007 as a measure to tackle the more challenging kinase, RNA-DNA processing and integral membrane protein families on our target list. Here, we discuss our platform for identifying soluble proteins from 3 ml of insect cell culture and describe the procedures involved in producing protein from liter-scale cultures. Although not discussed in this chapter, the same process can also be applied to integral membrane proteins (IMPs) with slight adaptations to the purification procedure

Achievements of the People in Place Project to Date (October 2005)

Achievements to date (October 2005) extracted from the end-of-year report submitted to the AHRC for the People in Place projec

Aims and Objectives for the First Year of the Research Grant (October 2003-October 2004)

This report on the aims and objectives for the first year of the research grant has been extracted from the end-of-year report submitted to the AHRC in October 200

Edited Summary of the Application to the Arts and Humanities Research Board (November 2002) for the People in Place Research Project

Edited summary of the application to the Arts and Humanities Research Board (November 2002), outlining aims, objectives and methodology of the People in Place research projec