Oral health and nutritional characteristics of adults with morbid obesity: a multivariate analysis.

The relationship between oral health and nutritional aspects are complex, especially in individuals with chronic diseases and comorbidities, such as morbid obesity. Thus, the aim of the present study was to identify oral health and nutritional-related patterns in 113 individuals, aged 19–68 years (92 females), seeking treatment for morbid obesity. Sociodemographic variables and medical records were examined, in addition to the consumption of fruit, vegetables, candies, and processed foods. Measures of body mass index, neck, waist and hip, caries experience (DMFT index), Community Periodontal Index (CPI index), and salivary physicochemical aspects were gathered. Aspects of oral health-related quality of life and symptoms of dry mouth were evaluated by means of Oral Health Impact Profile (OHIP-14) and Xerostomia Inventory-XI questionnaires. K-means cluster analysis and, subsequently, comparisons between clusters (one-way ANOVA) were performed (α = 5%). Three clusters were generated: Cluster 1 (labeled “Young”; n = 77) was characterized by younger participants with higher BMI, who reported the use of distractors while eating, the smallest number of meals/day, and who consumed sweetened drinks and processed food the day before. Cluster 2 (labeled “Diabetic individuals”; n = 12) was characterized by older participants with the highest proportion of diabetic participants (100% were diabetic; 73% insulin users), lower BMI, higher DMFT index and OHIP-14 and xerostomia scores, and who reported having consumed fruit and vegetables the day before. Finally, Cluster 3 (labeled “Poor periodontal health”; n = 24) was characterized by participants with the worse periodontal condition (higher CPI), and lower salivary flow, pH, and buffer capacity. Cluster 1 and 2 were the groups that showed higher demand for nutritional and dietetic counseling, because of the poor eating behavior and higher serum glucose levels, respectively. On the other hand, Cluster 2 and 3 showed the higher demand for oral rehabilitation and dental treatment because of the loss of teeth and worse periodontal condition, respectively, besides the need for dietetic counseling. This sample of individuals with morbid obesity showed very unique oral-health and nutritional characteristics and special needs patterns that should be identified to adjust or change unhealthy habits, thus improving the assistance of this condition

Efficacy of Conventional and Organic Insecticides against Scaphoideus titanus: Field and Semi-Field Trials

Scaphoideus titanus is the main vector of phytoplasmas associated with Flavescence dorée (FD), one of the most serious threats to viticulture in many European countries. To minimize the spread of this disease, mandatory control measures against S. titanus were decided in Europe. In the 1990s, the repeated application of insecticides (mainly organophosphates) proved to be an effective measure to control the vector and the related disease in north-eastern Italy. These insecticides and most of the neonicotinoids were recently banned from European viticulture. Serious FD issues detected in the recent years in northern Italy could be related to the use of less effective insecticides. Trials aimed at evaluating the efficacy of the most used conventional and organic insecticides in the control of S. titanus have been performed in semi-field and field conditions to test this hypothesis. In efficacy trials, carried out in four vineyards, etofenprox and deltamethrin proved to be the best conventional insecticides, while pyrethrins were the most impactful among organic insecticides. Insecticide residual activity was evaluated in semi-field and field conditions. Acrinathrin showed the most significant residual effects in both conditions. In semi-field trials, most of the pyrethroids were associated with good results in terms of residual activity. However, these effects declined in field conditions, probably due to high temperatures. Organic insecticides showed poor results in terms of residual efficacy. Implications of these results in the context of Integrated Pest Management in conventional and organic viticulture are discussed

Constraining stellar assembly and AGN feedback at the peak epoch of star formation

We study stellar assembly and feedback from active galactic nuclei (AGN) around the epoch of peak star formation (1<z<2), by comparing hydrodynamic simulations to rest-frame UV-optical galaxy colours from the Wide Field Camera 3 (WFC3) Early-Release Science (ERS) Programme. Our Adaptive Mesh Refinement simulations include metal-dependent radiative cooling, star formation, kinetic outflows due to supernova explosions, and feedback from supermassive black holes. Our model assumes that when gas accretes onto black holes, a fraction of the energy is used to form either thermal winds or sub-relativistic momentum-imparting collimated jets, depending on the accretion rate. We find that the predicted rest-frame UV-optical colours of galaxies in the model that includes AGN feedback is in broad agreement with the observed colours of the WFC3 ERS sample at 1<z<2. The predicted number of massive galaxies also matches well with observations in this redshift range. However, the massive galaxies are predicted to show higher levels of residual star formation activity than the observational estimates, suggesting the need for further suppression of star formation without significantly altering the stellar mass function. We discuss possible improvements, involving faster stellar assembly through enhanced star formation during galaxy mergers while star formation at the peak epoch is still modulated by the AGN feedback.Comment: 6 pages, 4 figures, accepted for publication in MNRAS Letter

The dusty, albeit ultraviolet bright infancy of galaxies

The largest galaxies acquire their mass early on, when the Universe is still youthful. Cold streams violently feed these young galaxies a vast amount of fresh gas, resulting in very efficient star formation. Using a well resolved hydrodynamical simulation of galaxy formation, we demonstrate that these mammoth galaxies are already in place a couple of billion years after the Big Bang. Contrary to local starforming galaxies, where dust re-emits a large part of the stellar ultraviolet (UV) light at infrared and sub-millimetre wavelengths, our self-consistent modelling of dust extinction predicts that a substantial fraction of UV photons should escape from primordial galaxies. Such a model allows us to compute reliably the number of high redshift objects as a function of luminosity, and yields galaxies whose UV luminosities closely match those measured in the deepest observational surveys available. This agreement is remarkably good considering our admittedly still simple modelling of the interstellar medium (ISM) physics. The luminosity functions (LF) of virtual UV luminous galaxies coincide with the existing data over the whole redshift range from 4 to 7, provided cosmological parameters are set to their currently favoured values. Despite their considerable emission at short wavelengths, we anticipate that the counterparts of the brightest UV galaxies will be detected by future sub-millimetre facilities like ALMAComment: 5 pages, 3 figures, submitted to MNRAS-le

Summer CO2 evasion from streams and rivers in the Kolyma River basin, north-east Siberia

Inland water systems are generally supersaturated in carbon dioxide (CO2) and are increasingly recognized as playing an important role in the global carbon cycle. The Arctic may be particularly important in this respect, given the abundance of inland waters and carbon contained in Arctic soils; however, a lack of trace gas measurements from small streams in the Arctic currently limits this understanding.We investigated the spatial variability of CO2 evasion during the summer low-flow period from streams and rivers in the northern portion of the Kolyma River basin in north-eastern Siberia. To this end, partial pressure of carbon dioxide (pCO2) and gas exchange velocities (k) were measured at a diverse set of streams and rivers to calculate CO2 evasion fluxes. We combined these CO2 evasion estimates with satellite remote sensing and geographic information system techniques to calculate total areal CO2 emissions. Our results show that small streams are substantial sources of atmospheric CO2 owing to high pCO2 and k, despite being a small portion of total inland water surface area. In contrast, large rivers were generally near equilibrium with atmospheric CO2. Extrapolating our findings across the Panteleikha-Ambolikha sub-watersheds demonstrated that small streams play a major role in CO2 evasion, accounting for 86% of the total summer CO2 emissions from inland waters within these two sub-watersheds. Further expansion of these regional CO2 emission estimates across time and space will be critical to accurately quantify and understand the role of Arctic streams and rivers in the global carbon budget

Extreme AGN Feedback and Cool Core Destruction in the X-ray Luminous Galaxy Cluster MACS J1931.8-2634

We report on a deep, multiwavelength study of the galaxy cluster MACS J1931.8-2634 using Chandra X-ray, Subaru optical, and VLA 1.4 GHz radio data. This cluster (z=0.352) harbors one of the most X-ray luminous cool cores yet discovered, with an equivalent mass cooling rate within the central 50 kpc is approximately 700 solar masses/yr. Unique features observed in the central core of MACSJ1931.8-2634 hint to a wealth of past activity that has greatly disrupted the original cool core. We observe a spiral of relatively cool, dense, X-ray emitting gas connected to the cool core, as well as highly elongated intracluster light (ICL) surrounding the cD galaxy. Extended radio emission is observed surrounding the central AGN, elongated in the east-west direction, spatially coincident with X-ray cavities. The power input required to inflate these `bubbles' is estimated from both the X-ray and radio emission to reside between 4 and 14e45 erg/s, putting it among the most powerful jets ever observed. This combination of a powerful AGN outburst and bulk motion of the cool core have resulted in two X-ray bright ridges to form to the north and south of the central AGN at a distance of approximately 25 kpc. The northern ridge has spectral characteristics typical of cool cores and is consistent with being a remnant of the cool core after it was disrupted by the AGN and bulk motions. It is also the site of H-alpha filaments and young stars. The X-ray spectroscopic cooling rate associated with this ridge is approximately 165 solar masses/yr, which agrees with the estimate of the star formation rate from broad-band optical imaging (170 solar masses/yr). MACS J1931.8-2634 appears to harbor one of most profoundly disrupted low entropy cores observed in a cluster, and offers new insights into the survivability of cool cores in the context of hierarchical structure formation.Comment: 19 pages, 15 figures, 5 tables. Accepted by MNRAS for publication September 30 201

Mass downsizing and "top-down" assembly of early-type galaxies

We present a new analysis of the rest-frame B-band COMBO-17 and DEEP2 luminosity functions (LFs) of early-type galaxies (ETGs) as a function of luminosity and mass. Our aim is to place new stringent constraints on the evolution of ETGs since z~1. We correct the LF($z$) data for the luminosity dimming assuming pure luminosity evolution. However, instead of relying on stellar population synthesis model--dependent assumptions, we adopt the empirical luminosity dimming rate derived from the evolution of the Fundamental Plane of field and cluster massive ETGs.Our results show that the amount of evolution for the ETG population depends critically on the range of luminosity and masses considered. While the number density of luminous (massive) ETGs with M_B(z=0) 10^11 M_Sun) is nearly constant since z~0.8, less luminous galaxies display a deficit which grows with redshift and that can be explained with a gradual population of the ETG "red sequence" by the progressive quenching of star formation in galaxies less massive than ~10^11 M_Sun. At each redshift there is a critical mass above which virtually all ETGs appear to be in place, and this fits well in the now popular "downsizing" scenario. However, ``downsizing'' does not appear to be limited to star formation, but the concept may have to be extended to the mass assembly itself as the build-up of the most massive galaxies preceeds that of the less massive ones. This evolutionary trend is not reproduced by the most recent theoretical simulations even when they successfully reproduce "downsizing" in star formation.Comment: Astronomy & Astrophysics (Letters), in press; 5 pages, 3 figure

Numerical simulations of the Warm-Hot Intergalactic Medium

In this paper we review the current predictions of numerical simulations for the origin and observability of the warm hot intergalactic medium (WHIM), the diffuse gas that contains up to 50 per cent of the baryons at z~0. During structure formation, gravitational accretion shocks emerging from collapsing regions gradually heat the intergalactic medium (IGM) to temperatures in the range T~10^5-10^7 K. The WHIM is predicted to radiate most of its energy in the ultraviolet (UV) and X-ray bands and to contribute a significant fraction of the soft X-ray background emission. While O VI and C IV absorption systems arising in the cooler fraction of the WHIM with T~10^5-10^5.5 K are seen in FUSE and HST observations, models agree that current X-ray telescopes such as Chandra and XMM-Newton do not have enough sensitivity to detect the hotter WHIM. However, future missions such as Constellation-X and XEUS might be able to detect both emission lines and absorption systems from highly ionised atoms such as O VII, O VIII and Fe XVII.Comment: 18 pages, 5 figures, accepted for publication in Space Science Reviews, special issue "Clusters of galaxies: beyond the thermal view", Editor J.S. Kaastra, Chapter 14; work done by an international team at the International Space Science Institute (ISSI), Bern, organised by J.S. Kaastra, A.M. Bykov, S. Schindler & J.A.M. Bleeke

Guillain-Barré syndrome and COVID-19: an observational multicentre study from two Italian hotspot regions

Objective: Single cases and small series of Guillain-Barré syndrome (GBS) have been reported during the SARS-CoV-2 outbreak worldwide. We evaluated incidence and clinical features of GBS in a cohort of patients from two regions of northern Italy with the highest number of patients with COVID-19. Methods: GBS cases diagnosed in 12 referral hospitals from Lombardy and Veneto in March and April 2020 were retrospectively collected. As a control population, GBS diagnosed in March and April 2019 in the same hospitals were considered. Results: Incidence of GBS in March and April 2020 was 0.202/100 000/month (estimated rate 2.43/100 000/year) vs 0.077/100 000/month (estimated rate 0.93/100 000/year) in the same months of 2019 with a 2.6-fold increase. Estimated incidence of GBS in COVID-19-positive patients was 47.9/100 000 and in the COVID-19-positive hospitalised patients was 236/100 000. COVID-19-positive patients with GBS, when compared with COVID-19-negative subjects, showed lower MRC sum score (26.3±18.3 vs 41.4±14.8, p=0.006), higher frequency of demyelinating subtype (76.6% vs 35.3%, p=0.011), more frequent low blood pressure (50% vs 11.8%, p=0.017) and higher rate of admission to intensive care unit (66.6% vs 17.6%, p=0.002). Conclusions: This study shows an increased incidence of GBS during the COVID-19 outbreak in northern Italy, supporting a pathogenic link. COVID-19-associated GBS is predominantly demyelinating and seems to be more severe than non-COVID-19 GBS, although it is likely that in some patients the systemic impairment due to COVID-19 might have contributed to the severity of the whole clinical picture

The Fermi Bubbles: Supersonic Active Galactic Nucleus Jets with Anisotropic Cosmic-Ray Diffusion

The Fermi Gamma-Ray Space Telescope reveals two large bubbles in the Galaxy, which extend nearly symmetrically ~50° above and below the Galactic center. Using three-dimensional (3D) magnetohydrodynamic simulations that self-consistently include the dynamical interaction between cosmic rays (CRs) and thermal gas and anisotropic CR diffusion along the magnetic field lines, we show that the key characteristics of the observed gamma-ray bubbles and the spatially correlated X-ray features in the ROSAT 1.5 keV map can be successfully reproduced by recent jet activity from the central active galactic nucleus. We find that after taking into account the projection of the 3D bubbles onto the sky the physical heights of the bubbles can be much smaller than previously thought, greatly reducing the formation time of the bubbles to about a Myr. This relatively small bubble age is needed to reconcile the simulations with the upper limit of bubble ages estimated from the cooling time of high-energy electrons. No additional physical mechanisms are required to suppress large-scale hydrodynamic instabilities because the evolution time is too short for them to develop. The simulated CR bubbles are edge-brightened, which is consistent with the observed projected flat surface brightness distribution. Furthermore, we demonstrate that the sharp edges of the observed bubbles can be due to anisotropic CR diffusion along magnetic field lines that drape around the bubbles during their supersonic expansion, with suppressed perpendicular diffusion across the bubble surface. Possible causes of the slight bends of the Fermi bubbles to the west are also discussed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98587/1/0004-637X_761_2_185.pd