6 research outputs found
The crystal structures of human α-thrombin complexed with active site-directed diamino benzo[b] thiophene derivatives: A binding mode for a structurally novel class of inhibitors
Full text linkDRUG OR TOOL, DESIGN OR SERENDIPITY
Get PDFIterative protein structure-based ligand design has led to a 'selective' inhibitor of human non-pancreatic secretory phospholipase A2 which provides a new tool for probing metabolic pathways and may lead to a useful drug.
