Overcoming seed dormancy in visgueiro-of-the-igapó (Parkia discolor)

This study aimed to evaluate the effects of pregerminative mechanical scarification treatments, as well as heat pre-treatments on the germination of visgueiro-of-the-igapó (Parkia discolor Spruce ex Benth.) seeds. The first experiment, with a completely randomized design and four repetitions, evaluated these pre-treatments: control (without pre-treatment); clipping at the distal portion; clipping at the proximal portion (hilum); clipping at the proximal and distal portions; scraping at the distal portion; scraping at the proximal portion; scraping at the proximal and distal portions; perforation of the husk with a soldering-iron; and perforation by pyrography. In the second experiment, with a completely randomized design and factorial 2 (heat: dry and wet) x 4 (temperature: 40ºC, 50ºC, 60ºC and 70ºC) x 5 (period of conditioning: 6, 16, 24, 30 and 48 hours), with three repetitions. The clipping or scraping of the seeds in the proximal portion and proximal and distal portions allowed faster imbibition of the seeds (143-163% in three days and half), and consequently, better germination (98-100% in four days), germination speed rate (1,351-1,460) and average time of germination (3 days). The pre-treatment with heat (wet and dry), under different temperatures and different conditioning periods did not overcome the dormancy of P. discolor seeds.O presente trabalho teve como objetivo avaliar os efeitos da aplicação de tratamentos pré-germinativos de escarificação mecânica, bem como pré-tratamentos com calor, sobre a germinação de sementes de visgueiro-do-igapó (Parkia discolor Spruce ex Benth.). No primeiro experimento, sob delineamento inteiramente ao acaso, com quatro repetições, foram avaliados os pré-tratamentostestemunha (sem pré-tratamento); desponte no lado distal; desponte no lado proximal; desponte nos lados distal e proximal; lixamento no lado distal; lixamento no lado proximal; lixamento nos lados distal e proximal; perfuração do tegumento com ferro-de-solda; e perfuração com pirógrafo. No segundo experimento, foi adotado o delineamento inteiramente casualizado, em esquema fatorial 2 (calorseco e úmido) x 4 (temperatura40ºC, 50ºC, 60ºC e 70ºC) x 5 (período de condicionamento6, 16, 24, 30 e 48 horas), com três repetições. O desponte ou lixamento das sementes na porção proximal e porções proximal e distal possibilitaram uma embebição mais rápida (143-163%, aos três dias e meio) e, conseqüentemente, melhores resultados de germinação (98-100%, aos quatro dias), do índice de velocidade de germinação (1,351-1,460) e do tempo médio de germinação (3 dias). Os pré-tratamentos com calor (úmido e seco), sob diferentes temperaturas, e por vários períodos de condicionamento não superaram a dormência de sementes de P. discolor

M. de Quatrefages on Gasteropod Mollusca

Volume: 14Start Page: 226End Page: 22

Gender, race and socioeconomic influence on diagnosis and treatment of thyroid disorders in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Thyroid diseases are common, and use of levothyroxine is increasing worldwide. We investigated the influence of gender, race and socioeconomic status on the diagnosis and treatment of thyroid disorders using data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), a multicenter cohort study of civil servants (35-74 years of age) from six Brazilian cities. Diagnosis of thyroid dysfunction was by thyrotropin (TSH), and free thyroxine (FT4) if TSH was altered, and the use of specific medications. Multivariate logistic regression models were constructed using overt hyperthyroidism/hypothyroidism and levothyroxine use as dependent variables and sociodemographic characteristics as independent variables. The frequencies of overt hyper- and hypothyroidism were 0.7 and 7.4%, respectively. Using whites as the reference ethnicity, brown, and black race were protective for overt hypothyroidism (OR=0.76, 95%CI=0.64-0.89, and OR=0.53, 95%CI=0.43-0.67, respectively, and black race was associated with overt hyperthyroidism (OR=1.82, 95%CI=1.06-3.11). Frequency of hypothyroidism treatment was higher in women, browns, highly educated participants and those with high net family incomes. After multivariate adjustment, levothyroxine use was associated with female gender (OR=6.06, 95%CI=3.19-11.49) and high net family income (OR=3.23, 95%CI=1.02-10.23). Frequency of hyperthyroidism treatment was higher in older than in younger individuals. Sociodemographic factors strongly influenced the diagnosis and treatment of thyroid disorders, including the use of levothyroxine

Predictors of health-related quality of life in patients with chronic liver disease

Background: Patient-reported outcomes such as HRQL have become increasingly important for patients with chronic liver disease (CLD). Aim: To explore the relative impact of different types of liver disease on HRQL as well as predictors of HRQL domains in CLD. Design: Our HRQL databases with Short-Form 36 data (SF-36) as well as clinico-demographic data were used. Scores for each of SF-36 scales (PF - physical functioning, RP - role functioning, BP - bodily pain, GH - general health, VT \u2013 vitality, SF - social functioning, RE - role emotional and MH - mental health, MCS- mental component score, PCS- physical component score) were compared between different types of CLD as well as other variables. SF-36 scales were compared using Wilcoxon tests. Spearman\u2019s rank coefficient was used as a measure of age-HRQL correlations. For all tests and correlation estimations, p-values not exceeding 0.05 after Benjamini-Hochberg correction were considered to be statistically significant. Results: Complete data was available for 1103 CLD patients. Demographic and clinical data included: age 53.7\ub111.8 years, 39% female, 792 (65%) with cirrhosis [357 (45%) Child\u2019s A, 274 (35%) Child\u2019s B and 161 (20%) Child\u2019s C)]. Analysis revealed that age correlated significantly (p<0.05) with worsening HRQL on every scale of the SF-36. Female patients had more HRQL impairments in PF, RP, BP, GH, VT and MH scales of SF-36 (Δ scale score: 6.6-10.7, p<0.05). Furthermore, cirrhotic patients had more impairment of HRQL in every scale of SF-36 (Δ scale score: 6.6-43.0, p<0.05). NAFLD patients had more impairment of HRQL. Conclusions: Analysis of this large cohort with CLD suggests a number of important clinico-demographic factors are associated with HRQL impairment. This data contributes to the full understanding of the total impact of CLD on patients and society