Topologically Protected Zero Modes in Twisted Bilayer Graphene

We show that the twisted graphene bilayer can reveal unusual topological properties at low energies, as a consequence of a Dirac-point splitting. These features rely on a symmetry analysis of the electron hopping between the two layers of graphene and we derive a simplified effective low-energy Hamiltonian which captures the essential topological properties of twisted bilayer graphene. The corresponding Landau levels peculiarly reveal a degenerate zero-energy mode which cannot be lifted by strong magnetic fields.Comment: 5 pages, 3 figures; published versio

The plasma picture of the fractional quantum Hall effect with internal SU(K) symmetries

We consider trial wavefunctions exhibiting SU(K) symmetry which may be well-suited to grasp the physics of the fractional quantum Hall effect with internal degrees of freedom. Systems of relevance may be either spin-unpolarized states (K=2), semiconductors bilayers (K=2,4) or graphene (K=4). We find that some introduced states are unstable, undergoing phase separation or phase transition. This allows us to strongly reduce the set of candidate wavefunctions eligible for a particular filling factor. The stability criteria are obtained with the help of Laughlin's plasma analogy, which we systematically generalize to the multicomponent SU(K) case. The validity of these criteria are corroborated by exact-diagonalization studies, for SU(2) and SU(4). Furthermore, we study the pair-correlation functions of the ground state and elementary charged excitations within the multicomponent plasma picture.Comment: 13 pages, 7 figures; reference added, accepted for publication in PR

Magnetic spectrum of trigonally warped bilayer graphene - semiclassical analysis, zero modes, and topological winding numbers

We investigate the fine structure in the energy spectrum of bilayer graphene in the presence of various stacking defaults, such as a translational or rotational mismatch. This fine structure consists of four Dirac points that move away from their original positions as a consequence of the mismatch and eventually merge in various manners. The different types of merging are described in terms of topological invariants (winding numbers) that determine the Landau-level spectrum in the presence of a magnetic field as well as the degeneracy of the levels. The Landau-level spectrum is, within a wide parameter range, well described by a semiclassical treatment that makes use of topological winding numbers. However, the latter need to be redefined at zero energy in the high-magnetic-field limit as well as in the vicinity of saddle points in the zero-field dispersion relation.Comment: 17 pages, 16 figures; published version with enhanced discussion of experimental finding

C-reactive protein and neutrophil count laboratory test requests from primary care:what is the demand and would substitution by point of care technology be viable?

Aims: C-reactive protein (CRP) and neutrophil count (NC) are important diagnostic indicators of inflammation. Point-of-care (POC) technologies for these markers are available but rarely used in community settings in the UK. To inform the potential for POC tests, it is necessary to understand the demand for testing. We aimed to describe the frequency of CRP and NC test requests from primary care to central laboratory services, describe variability between practices and assess the relationship between the tests.Methods: We described the number of patients with either or both laboratory tests, and the volume of testing per individual and per practice, in a retrospective cohort of all adults in general practices in Oxfordshire, 2014–2016.Results: 372 017 CRP and 776 581 NC tests in 160 883 and 275 093 patients, respectively, were requested from 69 practices. CRP was tested mainly in combination with NC, while the latter was more often tested alone. The median (IQR) of CRP and NC tests/person tested was 1 (1–2) and 2 (1–3), respectively. The median (IQR) tests/ practice/week was 36 (22–52) and 72 (50–108), and per 1000 persons registered/practice/week was 4 (3–5) and 8 (7–9), respectively. The median (IQR) CRP and NC concentrations were 2.7 (0.9–7.9)mg/dL and 4.1 (3.1–5.5)×109/L, respectively.Conclusions: The high demand for CRP and NC testing in the community, and the range of results falling within the reportable range for current POC technologies highlight the opportunity for laboratory testing to be supplemented by POC testing in general practice

Lifting the Dusty Veil With Near- and Mid-Infrared Photometry: III. Two-Dimensional Extinction Maps of the Galactic Midplane Using the Rayleigh-Jeans Color Excess Method

We provide new, high-resolution A(Ks) extinction maps of the heavily reddened Galactic midplane based on the Rayleigh-Jeans Color Excess ("RJCE") method. RJCE determines star-by-star reddening based on a combination of near- and mid-infrared photometry. The new RJCE-generated maps have 2 x 2 arcmin pixels and span some of the most severely extinguished regions of the Galaxy -- those covered with Spitzer+IRAC imaging by the GLIMPSE-I, -II, -3D, and Vela-Carina surveys, from 256<l<65 deg and, in general, for |b| <= 1-1.5 deg (extending up to |b|<=4 deg in the bulge). Using RJCE extinction measurements, we generate dereddened color-magnitude diagrams and, in turn, create maps based on main sequence, red clump, and red giant star tracers, each probing different distances and thereby providing coarse three-dimensional information on the relative placement of dust cloud structures. The maps generated from red giant stars, which reach to ~18-20 kpc, probe beyond most of the Milky Way extinction in most directions and provide close to a "total Galactic extinction" map -- at minimum they provide high angular resolution maps of lower limits on A(Ks). Because these maps are generated directly from measurements of reddening by the very dust being mapped, rather than inferred on the basis of some less direct means, they are likely the most accurate to date for charting in detail the highly patchy differential extinction in the Galactic midplane. We provide downloadable FITS files and an IDL tool for retrieving extinction values for any line of sight within our mapped regions.Comment: 23 pages, 5 figures, accepted for publication in ApJ

A batch-service queueing model with a discrete batch Markovian arrival process

Queueing systems with batch service have been investigated extensively during the past decades. However, nearly all the studied models share the common feature that an uncorrelated arrival process is considered, which is unrealistic in several real-life situations. In this paper, we study a discrete-time queueing model, with a server that only initiates service when the amount of customers in system (system content) reaches or exceeds a threshold. Correlation is taken into account by assuming a discrete batch Markovian arrival process (D-BMAP), i.e. the distribution of the number of customer arrivals per slot depends on a background state which is determined by a first-order Markov chain. We deduce the probability generating function of the system content at random slot marks and we examine the influence of correlation in the arrival process on the behavior of the system. We show that correlation merely has a small impact on the threshold that minimizes the mean system content. In addition, we demonstrate that correlation might have a significant influence on the system content and therefore has to be included in the model

Intervening in French: A Colony in Crisis, the Digital Humanities, and the French Classroom

This essay explore​s​ the use of *A Colony in Crisis: The Saint-Domingue Grain Crisis of 1789* in the French literature classroom and how it helps address gaps in digital humanities and French language pedagogy while interrogating the colonial positionality of the French Revolution’s digital archive. In 2015, the Newberry Library received a Digitizing Hidden Special Collections and Archives grant from the Council on Library and Information Resources (CLIR) to digitize 30,000 French language pamphlets, a portion of which pertains to the period before, during, and after the French Revolution. As the digital archive of the French Revolution rapidly grows, the need to draw attention to the broader context of revolution in the French Empire–particularly in the Caribbean–has become even more urgent. ​One of the most effective ways of addressing the marginalization of the Caribbean in colonial archives is through pedagogical interventions and course design. While digital humanities pedagogy has become somewhat normalized in the anglophone literature classroom, the French language classroom has been slow to adapt to the use of digital tools and pedagogy beyond the introductory language course

The APOGEE-2 Survey of the Orion Star Forming Complex: I. Target Selection and Validation with early observations

The Orion Star Forming Complex (OSFC) is a central target for the APOGEE-2 Young Cluster Survey. Existing membership catalogs span limited portions of the OSFC, reflecting the difficulty of selecting targets homogeneously across this extended, highly structured region. We have used data from wide field photometric surveys to produce a less biased parent sample of young stellar objects (YSOs) with infrared (IR) excesses indicative of warm circumstellar material or photometric variability at optical wavelengths across the full 420 square degrees extent of the OSFC. When restricted to YSO candidates with H < 12.4, to ensure S/N ~100 for a six visit source, this uniformly selected sample includes 1307 IR excess sources selected using criteria vetted by Koenig & Liesawitz and 990 optical variables identified in the Pan-STARRS1 3$\pi$ survey: 319 sources exhibit both optical variability and evidence of circumstellar disks through IR excess. Objects from this uniformly selected sample received the highest priority for targeting, but required fewer than half of the fibers on each APOGEE-2 plate. We fill the remaining fibers with previously confirmed and new color-magnitude selected candidate OSFC members. Radial velocity measurements from APOGEE-1 and new APOGEE-2 observations taken in the survey's first year indicate that ~90% of the uniformly selected targets have radial velocities consistent with Orion membership.The APOGEE-2 Orion survey will include >1100 bona fide YSOs whose uniform selection function will provide a robust sample for comparative analyses of the stellar populations and properties across all sub-regions of Orion.Comment: Accepted for publication in ApJ

Spatially Resolved 3 um Spectroscopy of IRAS 22272+5435: Formation and Evolution of Aliphatic Hydrocarbon Dust in Proto-Planetary Nebula

We present medium-resolution 3 um spectroscopy of the carbon-rich proto-planetary nebula IRAS 22272+5435. Spectroscopy with the Subaru Telescope adaptive optics system revealed a spatial variation of hydrocarbon molecules and dust surrounding the star. The ro-vibrational bands of acetylene (C2H2) and hydrogen cyanide (HCN) at 3.0 um are evident in the central star spectra. The molecules are concentrated in the compact region near the center. The 3.3 and 3.4 um emission of aromatic and aliphatic hydrocarbons is detected at 600--1300 AU from the central star. The separation of spatial distribution between gas and dust suggests that the small hydrocarbon molecules are indeed the source of solid material, and that the gas leftover from the grain formation is being observed near the central star. The intensity of aliphatic hydrocarbon emission relative to the aromatic hydrocarbon emission decreases with distance from the central star. The spectral variation is well matched to that of a laboratory analog thermally annealed with different temperatures. We suggest that either the thermal process after the formation of a grain or the variation in the temperature in the dust-forming region over time determines the chemical composition of the hydrocarbon dust around the proto-planetary nebula.Comment: 14 pages, 7 figures, Accepted for publication in the Astrophyical Journa

Improved results of induction chemoradiation before surgical intervention for selected patients with stage IIIA-N2 non–small cell lung cancer

ObjectiveOptimal management of stage IIIA-N2 non–small cell lung cancer remains controversial. The surgical arm of the North American Intergroup 0139 trial was adopted as the standard treatment for patients with resectable N2 disease at the University Health Network. Results after 7 years of experience are reported.MethodsThis is a retrospective study of consecutive patients with biopsy-proved T1-3 N2 M0 lung cancer who underwent induction chemoradiation before surgical intervention from January 1997 through August 2004. Induction chemotherapy consisted of cisplatin, 50 mg/m2, on days 1 and 8; etoposide, 50 mg/m2, on days 1 to 5, weeks 1 and 5; and concurrent daily external beam radiotherapy to 45 Gy. Lung resection was performed within 6 weeks of completion of chemoradiation, followed by 2 further cycles of consolidation chemotherapy.ResultsBetween January 1997 and August 2004, 40 patients were treated according to this protocol (25% T1, 62.5% T2, 7.5% T3, and 5% T4). Overall and disease-free median survivals were 40 and 37.1 months, respectively, whereas overall and disease-free 3-year survivals were 51.7% and 52.3%, respectively. R0 resection was achieved in 92.5%. The overall operative mortality rate was 7.5% (0% for lobectomy and 27% for pneumonectomy). Notably, all mortalities occurred within the first 2 years of our experience with this regimen.ConclusionChemoradiation before pulmonary resection in carefully selected patients with surgically resectable stage IIIA (N2) non–small cell lung cancer can lead to improved overall and disease-free survival