16 research outputs found
ORGAN AND TISSUE RADIOACTIVITY FOLLOWING PARENTERAL ADMINISTRATION OF Co VITAMIN B
Vitamin B/sub 12/, labeled with Co/sup 60/ having a specific activity of 1.0 mu C/ mu g, was administered to 18 patients in the late stages of malignandt diseases. Death occurred 11 hr to 695 days after Co -- B/sub 12/ administration. Data are presented on the distribution of Co -- B/sub 12/ in tissues andd organds obtained at post-mortem examination. From 16.8 to 108% was in the liver, with lesser amounts in the othef organds and tissues. Variations resulted from the route of administration, disesse state, and interval between administration and death. (C.H.