150 research outputs found
Radiative and non-radiative local density of states on disordered plasmonic films
We present numerical calculations of the Local Density of Optical States
(LDOS) in the near field of disordered plasmonic films. The calculations are
based on an integral volume method, that takes into account polarization and
retardation effects, and allows us to discriminate radiative and non-radiative
contributions to the LDOS. At short distance, the LDOS is dominated by
non-radiative channels, showing that changes in the spontaneous dynamics of
dipole emitters are driven by non-radiative coupling to plasmon modes. Maps of
radiative and non-radiative LDOS exhibit strong fluctuations, but with
substantially different spatial distributions
First-Principle Homogenization Theory for Periodic Metamaterials
We derive from first principles an accurate homogenized description of
periodic metamaterials made of magnetodielectric inclusions, highlighting and
overcoming relevant limitations of standard homogenization methods. We obtain
closed-form expressions for the effective constitutive parameters, pointing out
the relevance of inherent spatial dispersion effects, present even in the
long-wavelength limit. Our results clarify the limitations of quasi-static
homogenization models, restore the physical meaning of homogenized metamaterial
parameters and outline the reasons behind magnetoelectric coupling effects that
may arise also in the case of center-symmetric inclusions.Comment: 58 pages, 10 figures Phys. Rev. B, in press (2011
Quantized Roentgen Effect in Bose-Einstein Condensates
A classical dielectric moving in a charged capacitor can create a magnetic
field (Roentgen effect). A quantum dielectric, however, will not produce a
magnetization, except at vortices. The magnetic field outside the quantum
dielectric appears as the field of quantized monopoles
A rigorous analysis of high order electromagnetic invisibility cloaks
There is currently a great deal of interest in the invisibility cloaks
recently proposed by Pendry et al. that are based in the transformation
approach. They obtained their results using first order transformations. In
recent papers Hendi et al. and Cai et al. considered invisibility cloaks with
high order transformations. In this paper we study high order electromagnetic
invisibility cloaks in transformation media obtained by high order
transformations from general anisotropic media. We consider the case where
there is a finite number of spherical cloaks located in different points in
space. We prove that for any incident plane wave, at any frequency, the
scattered wave is identically zero. We also consider the scattering of finite
energy wave packets. We prove that the scattering matrix is the identity, i.e.,
that for any incoming wave packet the outgoing wave packet is the same as the
incoming one. This proves that the invisibility cloaks can not be detected in
any scattering experiment with electromagnetic waves in high order
transformation media, and in particular in the first order transformation media
of Pendry et al. We also prove that the high order invisibility cloaks, as well
as the first order ones, cloak passive and active devices. The cloaked objects
completely decouple from the exterior. Actually, the cloaking outside is
independent of what is inside the cloaked objects. The electromagnetic waves
inside the cloaked objects can not leave the concealed regions and viceversa,
the electromagnetic waves outside the cloaked objects can not go inside the
concealed regions. As we prove our results for media that are obtained by
transformation from general anisotropic materials, we prove that it is possible
to cloak objects inside general crystals.Comment: The final version is now published in Journal of Physics A:
Mathematical and Theoretical, vol 41 (2008) 065207 (21 pp). Included in
IOP-Selec
Gauge Theories with Cayley-Klein and Gauge Groups
Gauge theories with the orthogonal Cayley-Klein gauge groups and
are regarded. For nilpotent values of the contraction
parameters these groups are isomorphic to the non-semisimple Euclid,
Newton, Galilei groups and corresponding matter spaces are fiber spaces with
degenerate metrics. It is shown that the contracted gauge field theories
describe the same set of fields and particle mass as gauge
theories, if Lagrangians in the base and in the fibers all are taken into
account. Such theories based on non-semisimple contracted group provide more
simple field interactions as compared with the initial ones.Comment: 14 pages, 5 figure
Platelets of patients with chronic kidney disease demonstrate deficient platelet reactivity in vitro
<p>Abstract</p> <p>Background</p> <p>In patients with chronic kidney disease studies focusing on platelet function and properties often are non-conclusive whereas only few studies use functional platelet tests. In this study we evaluated a recently developed functional flow cytometry based assay for the analysis of platelet function in chronic kidney disease.</p> <p>Methods</p> <p>Platelet reactivity was measured using flow cytometric analysis. Platelets in whole blood were triggered with different concentrations of agonists (TRAP, ADP, CRP). Platelet activation was quantified with staining for P-selectin, measuring the mean fluorescence intensity. Area under the curve and the concentration of half-maximal response were determined.</p> <p>Results</p> <p>We studied 23 patients with chronic kidney disease (9 patients with cardiorenal failure and 14 patients with end stage renal disease) and 19 healthy controls. Expression of P-selectin on the platelet surface measured as mean fluorescence intensity was significantly less in chronic kidney disease patients compared to controls after maximal stimulation with TRAP (9.7 (7.9-10.8) vs. 11.4 (9.2-12.2), Pâ=â0.032), ADP (1.6 (1.2-2.1) vs. 2.6 (1.9-3.5), Pâ=â0.002) and CRP (9.2 (8.5-10.8) vs. 11.5 (9.5-12.9), Pâ=â0.004). Also the area under the curve was significantly different. There was no significant difference in half-maximal response between both groups.</p> <p>Conclusion</p> <p>In this study we found that patients with chronic kidney disease show reduced platelet reactivity in response of ADP, TRAP and CRP compared to controls. These results contribute to our understanding of the aberrant platelet function observed in patients with chronic kidney disease and emphasize the significance of using functional whole blood platelet activation assays.</p
A significant proportion of classic Hodgkin lymphoma recurrences represents clonally unrelated second primary lymphoma
Despite high cure rates in classic Hodgkin lymphoma (cHL), relapses are observed. Whether relapsed cHL represents second primary lymphoma or an underlying T-cell lymphoma (TCL) mimicking cHL is under-investigated. To analyze the nature of cHL recurrences, in-depth clonality testing of immunoglobulin (IG) and T-cell receptor (TR) rearrangements was performed in paired cHL diagnosis and recurrences of 60 patients, supported by targeted mutation analysis of lymphoma-associated genes. Clonal IG rearrangements were detected by next-generation sequencing (NGS) in 69/120 (58%) diagnosis and recurrence samples. The clonal relationship could be established in 34 cases, identifying clonally related relapsed cHL in 24/34 patients (71%). Clonally unrelated cHL was observed in 10/34 patients (29%) as determined by IG-NGS clonality assessment, and confirmed by the identification of predominantly mutually exclusive gene mutations in the paired cHL samples. In recurrences of >2 years, ~60% of cHL patients for which the clonal relationship could be established showed a second primary cHL. Clonal TR gene rearrangements were identified in 14/125 samples (11%), and TCL-associated gene mutations were detected in 7/14 samples. Retrospective pathology review with integration of the molecular findings were consistent with an underlying TCL in 5 patients aged >50 years. This study shows that cHL recurrences, especially after 2 years, sometimes represent a new primary cHL or TCL mimicking cHL, as uncovered by NGS-based IG/TR clonality testing and gene mutation analysis. Given the significant therapeutic consequences, molecular testing of a presumed relapse in cHL is crucial for subsequent appropriate treatment strategies adapted to the specific lymphoma presentation.</p
On the derivative of the associated Legendre function of the first kind of integer order with respect to its degree
In our recent works [R. Szmytkowski, J. Phys. A 39 (2006) 15147; corrigendum:
40 (2007) 7819; addendum: 40 (2007) 14887], we have investigated the derivative
of the Legendre function of the first kind, , with respect to its
degree . In the present work, we extend these studies and construct
several representations of the derivative of the associated Legendre function
of the first kind, , with respect to the degree , for
. At first, we establish several contour-integral
representations of . They are then
used to derive Rodrigues-type formulas for with . Next, some closed-form
expressions for are
obtained. These results are applied to find several representations, both
explicit and of the Rodrigues type, for the associated Legendre function of the
second kind of integer degree and order, ; the explicit
representations are suitable for use for numerical purposes in various regions
of the complex -plane. Finally, the derivatives
, and , all with , are evaluated in terms
of .Comment: LateX, 40 pages, 1 figure, extensive referencin
- âŠ