528 research outputs found
PPAR Alpha Regulation of the Immune Response and Autoimmune Encephalomyelitis
PPARs are members of the steroid hormone nuclear receptor superfamily and play an important role in the regulation of lipid metabolism, energy balance, artherosclerosis and glucose control. Recent studies suggest that they play an important role in regulating inflammation. This review will focus on PPAR-α regulation of the immune response. We describe how PPAR-α regulates differentiation of T cells by transactivation and/or interaction with other transcription factors. Moreover, PPAR-α agonists have been shown to ameliorate experimental autoimmune encephalomyelitis (EAE) in mice, suggesting that they could provide a therapy for human autoimmune diseases such as multiple sclerosis
Heat conduction in elastic systems : fourier versus cattaneo
Papers presented to the 11th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, South Africa, 20-23 July 2015.Please read abstract in article.am201
Energy decay for Timoshenko systems of memory type
AbstractLinear systems of Timoshenko type equations for beams including a memory term are studied. The exponential decay is proved for exponential kernels, while polynomial kernels are shown to lead to a polynomial decay. The optimality of the results is also investigated
On the Nature of Singularities in Plane Symmetric Scalar Field Cosmologies
The nature of the initial singularity in spatially compact plane symmetric
scalar field cosmologies is investigated. It is shown that this singularity is
crushing and velocity dominated and that the Kretschmann scalar diverges
uniformly as it is approached. The last fact means in particular that a maximal
globally hyperbolic spacetime in this class cannot be extended towards the past
through a Cauchy horizon. A subclass of these spacetimes is identified for
which the singularity is isotropic.Comment: 7 pages, MPA-AR-94-
A class of plane symmetric perfect-fluid cosmologies with a Kasner-like singularity
We prove the existence of a class of plane symmetric perfect-fluid
cosmologies with a (-1/3, 2/3, 2/3) Kasner-like singularity. These solutions of
the Einstein equations depend on two smooth functions of one space coordinate.
They are constructed by solving a symmetric hyperbolic system of Fuchsian
equations.Comment: LaTeX, 15 pages, no figures, to appear in CQG, correction to
existence proo
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