4,249 research outputs found
Anomalously light mesons in a (1+1)-dimensional supersymmetric theory with fundamental matter
We consider N=1 supersymmetric Yang-Mills theory with fundamental matter in
the large-N_c approximation in 1+1 dimensions. We add a Chern-Simons term to
give the adjoint partons a mass and solve for the meson bound states. Here
mesons are color-singlet states with two partons in the fundamental
representation but are not necessarily bosons. We find that this theory has
anomalously light meson bound states at intermediate and strong coupling. We
also examine the structure functions for these states and find that they prefer
to have as many partons as possible at low longitudinal momentum fraction.Comment: 14 pages, 3 figures, LaTe
Use of minimally invasive hemodynamic monitoring to assess dynamic changes in cardiac output at the bedside
Hemodynamic monitoring over the past 10 years
Changes in hemodynamic monitoring over the past 10 years have followed two paths. First, there has been a progressive decrease in invasive monitoring, most notably a reduction in the use of the pulmonary artery catheter because of a presumed lack of efficacy in its use in the management of critically ill patients, with an increased use of less invasive monitoring requiring only central venous and arterial catheterization to derive the same data. Second, numerous clinical trials have documented improved outcome and decreased costs when early goal-directed protocolized therapies are used in appropriate patient populations, such as patients with septic shock presenting to Emergency Departments and high-risk surgical patients before surgery (pre-optimization) and immediately after surgery (post-optimization). Novel monitoring will be driven more by its role in improving outcomes than in the technical abilities of the manufacturers
Toward a better ventilation strategy for patients with acute lung injury
Ventilator-induced lung injury is a major outcome determinant of the acute respiratory distress syndrome (ARDS). Ventilatory strategies that limit ventilator-induced lung injury should improve outcome from ARDS. The ARDSnet trial showed improved survival in subjects ventilated with a lower tidal volume. Although this trial developed and tested a rigorous clinical protocol, it did not define the limits to which tidal volume reduction would benefit outcome. It is also not at all clear if it is the reduction in tidal volume or the reduction in plateau airway pressure that confers this benefit. Finally, ventilator-induced lung injury occurs more commonly from repetitive collapse and re-expansion of injured lung units rather than from the overdistention of persistently aerated lung units. This was not addressed in the trial design. Thus, further study using targeted open-lung strategies are also needed
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