Electron cyclotron maser emission mode coupling to the z-mode on a longitudinal density gradient in the context of solar type III bursts

Copyright 2012 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. This article appeared in Physics of Plasmas 19, 110702 (2012) and may be found at .supplemental material at http://astro.qmul.ac.uk/~tsiklauri/sp.htmlsupplemental material at http://astro.qmul.ac.uk/~tsiklauri/sp.htm

The effect of electron beam pitch angle and density gradient on solar type III radio bursts

Copyright 2012 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. This article appeared in Physics of Plasmas 19, 112903 (2012) and may be found at .supplemental material at http://astro.qmul.ac.uk/~tsiklauri/sp.htmlsupplemental material at http://astro.qmul.ac.uk/~tsiklauri/sp.htm

Heating of solar chromosphere by electromagnetic wave absorption in a plasma slab model

The heating of solar chromospheric inter-network regions by means of the absorption of electromagnetic (EM) waves that originate from the photospheric blackbody radiation is studied in the framework of a plasma slab model. The absorption is provided by the electron-neutral collisions in which electrons oscillate in the EM wave field and electron-neutral collisions damp the EM wave. Given the uncertain nature of the collision cross-section due to the plasma micro-turbulence, it is shown that for plausible physical parameters, the heating flux produced by the absorption of EM waves in the chromosphere is between $20 - 45$ % of the chromospheric radiative loss flux requirement. It is also established that there is an optimal value for the collision cross-section, $5 \times 10^{-18}$ m$^{2}$, that produces the maximal heating flux of 1990 W m$^{-2}$.Comment: Physics of Plasmas, in press, April 2011 issue (final printed version, typos in proofs corrected

Natural History of Autosomal Recessive <i>IMPG2</i>-Associated Retinal Dystrophy

Purpose: To describe the natural history of autosomal recessive IMPG2-associated retinal dystrophy. Design: Multicenter international retrospective case series. Methods: Review of clinical notes, retinal imaging including fundus autofluorescence (FAF) and optical coherence tomography (OCT), and molecular genetic testing, of sixty patients with molecularly confirmed IMPG2-associated retinal dystrophy from 14 tertiary eye centers. Qualitative OCT and FAF imaging analysis. Results: In total, 60 patients from 52 pedigrees with likely disease-causing variants in IMPG2 from 14 tertiary referral centers in 11 countries were ascertained for phenotyping. Twenty-two patients were females (36.7%). Of those with documented age of disease onset, 23% had “late onset” (&gt;18 years old [yo]) with a mean age of onset of 34.3 yo, and 77% had “early onset” disease (&lt;18 yo) with a mean age of onset of 10.8 yo. Mean best-corrected visual acuity (BCVA) was 0.55 LogMAR at a mean age of 33 yo. Forty-eight percent of the patients presented with nyctalopia and 38% presented with decreased BCVA. Eighty-eight percent of the patients were myopic. Foveal involvement with atrophic changes was a common finding on OCT and FAF. Fifty-three variants were identified: 13 missense (25%), 12 nonsense (23%), 11 splicing variants (21%), 16 frameshifts (30%), and one large deletion (2%). Twenty-one (40%) of the variants were not previously clinically characterized. Conclusion: Autosomal recessive IMPG2-retinal dystrophy is typically an early onset retinal dystrophy associated with poor visual acuity. Younger patients are more likely to benefit from intervention in future trials due to early macular involvement in most patients.</p

Bardet-Biedl syndrome improved diagnosis criteria and management: Inter European Reference Networks consensus statement and recommendations

Four European Reference Networks (ERN-EYE, ERKNet, Endo-ERN, ERN-ITHACA) have teamed up to establish a consensus statement and recommendations for Bardet-Biedl syndrome (BBS). BBS is an autosomal recessive ciliopathy with at least 26 genes identified to date. The clinical manifestations are pleiotropic, can be observed in utero and will progress with age. Genetic testing has progressively improved in the last years prompting for a revision of the diagnostic criteria taking into account clinical Primary and Secondary features, as well as positive or negative molecular diagnosis. This consensus statement also emphasizes on initial diagnosis, monitoring and lifelong follow-up, and symptomatic care that can be provided to patients and family members according to the involved care professionals. For paediatricians, developmental anomalies can be at the forefront for diagnosis (such as polydactyly) but can require specific care, such as for associated neuro developmental disorders. For ophthalmology, the early onset retinal degeneration requires ad hoc functional and imaging technologies and specific care for severe visual impairment. For endocrinology, among other manifestations, early onset obesity and its complications has benefited from better evaluation of eating behaviour problems, improved lifestyle programs, and from novel pharmacological therapies. Kidney and urinary track involvements warrants lifespan attention, as chronic kidney failure can occur and early management might improve outcome. This consensus recommends revised diagnostic criteria for BBS that will ensure certainty of diagnosis, giving robust grounds for genetic counselling as well as in the perspective of future trials for innovative therapies

14. Die botanische Herkunftsbestimmung des Honigs: zum Problem der Aussagekraft der Honigpollenanalyse

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38. Test verschiedener Methoden einer Ameisensäure-Langzeitbehandlung zur Varroabekämpfung

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