Standard-like Models as Type IIB Flux Vacua

We construct new semi-realistic Type IIB flux vacua on $Z_2\times Z_2$ orientifolds with three- and four- Standard Model (SM) families and up to three units of quantized flux. The open-string sector is comprised of magnetized D-branes and is T-dual to supersymmetric intersecting D6-brane constructions. The SM sector contains magnetized D9-branes with negative D3-brane charge contribution. There are large classes of such models and we present explicit constructions for representative ones. In addition to models with one and two units of quantized flux, we also construct the first three- and four-family Standard-like models with supersymmetric fluxes, i.e. comprising three units of quantized flux. Supergravity fluxes are due to the self-dual NS-NS and R-R three-form field strength and they fix the toroidal complex structure moduli and the dilaton. The supersymmetry conditions for the D-brane sector fix in some models all three toroidal K\"ahler moduli. We also provide examples where toroidal K\" ahler moduli are fixed by strong gauge dynamics on the ``hidden sector'' D7-brane. Most of the models possess Higgs doublet pairs with Yukawa couplings that can generate masses for quarks and leptons. The models have (mainly right-) chiral exotics.Comment: 31 page

Connecting protein and mRNA burst distributions for stochastic models of gene expression

The intrinsic stochasticity of gene expression can lead to large variability in protein levels for genetically identical cells. Such variability in protein levels can arise from infrequent synthesis of mRNAs which in turn give rise to bursts of protein expression. Protein expression occurring in bursts has indeed been observed experimentally and recent studies have also found evidence for transcriptional bursting, i.e. production of mRNAs in bursts. Given that there are distinct experimental techniques for quantifying the noise at different stages of gene expression, it is of interest to derive analytical results connecting experimental observations at different levels. In this work, we consider stochastic models of gene expression for which mRNA and protein production occurs in independent bursts. For such models, we derive analytical expressions connecting protein and mRNA burst distributions which show how the functional form of the mRNA burst distribution can be inferred from the protein burst distribution. Additionally, if gene expression is repressed such that observed protein bursts arise only from single mRNAs, we show how observations of protein burst distributions (repressed and unrepressed) can be used to completely determine the mRNA burst distribution. Assuming independent contributions from individual bursts, we derive analytical expressions connecting means and variances for burst and steady-state protein distributions. Finally, we validate our general analytical results by considering a specific reaction scheme involving regulation of protein bursts by small RNAs. For a range of parameters, we derive analytical expressions for regulated protein distributions that are validated using stochastic simulations. The analytical results obtained in this work can thus serve as useful inputs for a broad range of studies focusing on stochasticity in gene expression

Energy flux fluctuations in a finite volume of turbulent flow

The flux of turbulent kinetic energy from large to small spatial scales is measured in a small domain B of varying size R. The probability distribution function of the flux is obtained using a time-local version of Kolmogorov's four-fifths law. The measurements, made at a moderate Reynolds number, show frequent events where the flux is backscattered from small to large scales, their frequency increasing as R is decreased. The observations are corroborated by a numerical simulation based on the motion of many particles and on an explicit form of the eddy damping.Comment: 10 Pages, 5 figures, 1 tabl

Charge-ordering, commensurability and metallicity in the phase diagram of layered Na(x)CoO(2)

The phase diagram of non-hydrated Na(x)CoO(2) has been determined by changing the Na content x using a series of chemical reactions. As x increases from 0.3, the ground state goes from a paramagnetic metal to a charge-ordered insulator (at x=1/2) to a `Curie-Weiss metal' (around 0.70), and finally to a weak-moment magnetically ordered state (x>0.75). The unusual properties of the state at 1/2 (including particle-hole symmetry at low T and enhanced thermal conductivity) are described. The strong coupling between the Na ions and the holes is emphasized.Comment: 4 pages with 3 figures, changed conten

Competitive market for multiple firms and economic crisis

The origin of economic crises is a key problem for economics. We present a model of long-run competitive markets to show that the multiplicity of behaviors in an economic system, over a long time scale, emerge as statistical regularities (perfectly competitive markets obey Bose-Einstein statistics and purely monopolistic-competitive markets obey Boltzmann statistics) and that how interaction among firms influences the evolutionary of competitive markets. It has been widely accepted that perfect competition is most efficient. Our study shows that the perfectly competitive system, as an extreme case of competitive markets, is most efficient but not stable, and gives rise to economic crises as society reaches full employment. In the economic crisis revealed by our model, many firms condense (collapse) into the lowest supply level (zero supply, namely bankruptcy status), in analogy to Bose-Einstein condensation. This curious phenomenon arises because perfect competition (homogeneous competitions) equals symmetric (indistinguishable) investment direction, a fact abhorred by nature. Therefore, we urge the promotion of monopolistic competition (heterogeneous competitions) rather than perfect competition. To provide early warning of economic crises, we introduce a resolving index of investment, which approaches zero in the run-up to an economic crisis. On the other hand, our model discloses, as a profound conclusion, that the technological level for a long-run social or economic system is proportional to the freedom (disorder) of this system; in other words, technology equals the entropy of system. As an application of this new concept, we give a possible answer to the Needham question: "Why was it that despite the immense achievements of traditional China it had been in Europe and not in China that the scientific and industrial revolutions occurred?"Comment: 17 pages; 3 figure

Four-quark state in QCD

The spectra of some 0++ four-quark states, which are composed of \bar qq pairs, are calculated in QCD. The light four-quark states are calculated using the traditional sum rules while four-quark states containing one heavy quark are computed in HQET. For constructing the interpolating currents, different couplings of the color and spin inside the \bar qq pair are taken into account. It is found that the spin and color combination has little effect on the mass of the four-quark states.Comment: 10 pages, 4 ps figures, Late

DC-conductivity of a suspension of insulating particles with internal rotation

We analyse the consequences of Quincke rotation on the conductivity of a suspension. Quincke rotation refers to the spontaneous rotation of insulating particles dispersed in a slightly conducting liquid and subject to a high DC electric field: above a critical field, each particle rotates continuously around itself with an axis pointing in any direction perpendicular to the DC field. When the suspension is subject to an electric field lower than the threshold one, the presence of insulating particles in the host liquid decreases the bulk conductivity since the particles form obstacles to ion migration. But for electric fields higher than the critical one, the particles rotate and facilitate ion migration: the effective conductivity of the suspension is increased. We provide a theoretical analysis of the impact of Quincke rotation on the apparent conductivity of a suspension and we present experimental results obtained with a suspension of PMMA particles dispersed in weakly conducting liquids