Survey of Australian father\u27s attitudes towards infant vaccination: Findings from the Australian Father\u27s Study

Objective: To investigate the attitudes of expectant Australian fathers towards vaccination, and to identify factors which may influence these attitudes. Methods: A cross-sectional survey study of 407 Australian men with expectant partners, mean age 30.4 (SD 6.7). Self reported attitude, level of knowledge and information resources accessed regarding pregnancy related issues. Participant demographics collected included: Age, number of children, relationship status, level of education, employment information and smoking status. Results: Majority (89%) of participants had a positive attitude towards infant vaccination, 9% felt neutral and 2% had negative attitudes. Positive attitudes towards vaccination were associated with lower self-reported knowledge of pregnancy issues but a higher likelihood of discussing pregnancy issues with health care providers rather than sourcing information from the internet (both p\u3c0.001). Conclusion: A majority of Australian expectant fathers have a positive attitude towards infant vaccination. Fathers with negative attitudes to vaccination self-reported higher levels of knowledge. They were more likely to obtain information from the Internet instead of healthcare staff. Implication for public health: Including fathers in health discussion with knowledgeable health care providers may result in increased vaccine uptake

Enhancement of in vitro Guayule propagation

A method for stimulating in vitro propagation of Guayule from a nutrient medium containing Guayule tissue by adding a substituted trialkyl amine bioinducing agent to the nutrient medium is described. Selective or differentiated propagation of shoots or callus is obtained by varying the amounts of substituted trialky amine present in the nutrient medium. The luxuriant growth provided may be processed for its poly isoprene content or may be transferred to a rooting medium for production of whole plants as identical clones of the original tissue. The method also provides for the production of large numbers of Guayule plants having identical desirable properties such as high polyisoprene levels

Methods for measuring the citations and productivity of scientists across time and discipline

Publication statistics are ubiquitous in the ratings of scientific achievement, with citation counts and paper tallies factoring into an individual's consideration for postdoctoral positions, junior faculty, tenure, and even visa status for international scientists. Citation statistics are designed to quantify individual career achievement, both at the level of a single publication, and over an individual's entire career. While some academic careers are defined by a few significant papers (possibly out of many), other academic careers are defined by the cumulative contribution made by the author's publications to the body of science. Several metrics have been formulated to quantify an individual's publication career, yet none of these metrics account for the dependence of citation counts and journal size on time. In this paper, we normalize publication metrics across both time and discipline in order to achieve a universal framework for analyzing and comparing scientific achievement. We study the publication careers of individual authors over the 50-year period 1958-2008 within six high-impact journals: CELL, the New England Journal of Medicine (NEJM), Nature, the Proceedings of the National Academy of Science (PNAS), Physical Review Letters (PRL), and Science. In comparing the achievement of authors within each journal, we uncover quantifiable statistical regularity in the probability density function (pdf) of scientific achievement across both time and discipline. The universal distribution of career success within these arenas for publication raises the possibility that a fundamental driving force underlying scientific achievement is the competitive nature of scientific advancement.Comment: 25 pages in 1 Column Preprint format, 7 Figures, 4 Tables. Version II: changes made in response to referee comments. Note: change in definition of "Paper shares.

Recovery of Viable Microorganisms from Solids. I - Model Systems

Solidification process for recovering viable microorganisms to aid spacecraft sterilization procedure

Use of ERTS-1 data to assess and monitor change in the Southern California environment

There are no author-identified significant results in this report

Obese Subjects Show Sex-Specific Differences in Right Ventricular Hypertrophy

As right ventricular (RV) remodeling in obesity remains underinvestigated, and the impact of left ventricular (LV) diastolic dysfunction on RV hypertrophy is unknown, we aimed to investigate whether (1) sex-specific patterns of RV remodeling exist in obesity and (2) LV diastolic dysfunction in obesity is related to RV hypertrophy.Seven hundred thirty-nine subjects (women, n=345; men, n=394) without identifiable cardiovascular risk factors (body mass index [BMI], 15.3-59.2 kg/m2) underwent cardiovascular magnetic resonance (1.5 T) to measure RV mass (g), RV end-diastolic volume (mL), RV mass/volume ratio, and LV diastolic peak filling rate (mL/s). All subjects were normotensive (average, 119±11/73±8 mm Hg), normoglycaemic (4.8±0.5 mmol/L), and normocholesterolaemic (4.8±0.9 mmol/L) at the time of scanning. Across both sexes, there was a moderately strong positive correlation between BMI and RV mass (men, +0.8 g per BMI point increase; women, +1.0 g per BMI point increase; both P<0.001). Whereas women exhibited RV cavity dilatation (RV end-diastolic volume, +1.0 mL per BMI point increase; P<0.001), BMI was not correlated with RV end-diastolic volume in men (R=0.04; P=0.51). Concentric RV remodeling was present in both sexes, with RV mass/volume ratio being positively correlated to BMI (men, R=0.41; women, R=0.51; both P<0.001). Irrespective of sex, the LV peak filling rate was negatively correlated with both RV mass (men, R=-0.43; women, R=-0.44; both P<0.001) and RV mass/volume ratio (men, R=-0.37; women, R=-0.35; both P<0.001).A sex difference in RV remodeling exists in obesity. Whereas men exhibit concentric RV remodeling, women exhibit a mixed pattern of eccentric and concentric remodeling. Regardless of sex, reduced LV diastolic function is associated with concentric RV remodeling

Functionally Annotating Regulatory Elements in the Equine Genome Using Histone Mark ChIP-Seq.

One of the primary aims of the Functional Annotation of ANimal Genomes (FAANG) initiative is to characterize tissue-specific regulation within animal genomes. To this end, we used chromatin immunoprecipitation followed by sequencing (ChIP-Seq) to map four histone modifications (H3K4me1, H3K4me3, H3K27ac, and H3K27me3) in eight prioritized tissues collected as part of the FAANG equine biobank from two thoroughbred mares. Data were generated according to optimized experimental parameters developed during quality control testing. To ensure that we obtained sufficient ChIP and successful peak-calling, data and peak-calls were assessed using six quality metrics, replicate comparisons, and site-specific evaluations. Tissue specificity was explored by identifying binding motifs within unique active regions, and motifs were further characterized by gene ontology (GO) and protein-protein interaction analyses. The histone marks identified in this study represent some of the first resources for tissue-specific regulation within the equine genome. As such, these publicly available annotation data can be used to advance equine studies investigating health, performance, reproduction, and other traits of economic interest in the horse

Chalcogenide-glass polarization-maintaining photonic crystal fiber for mid-infrared supercontinuum generation

In this paper, we report the design and fabrication of a highly birefringent polarization-maintaining photonic crystal fiber (PM-PCF) made from chalcogenide glass, and its application to linearly-polarized supercontinuum (SC) generation in the mid-infrared region. The PM fiber was drawn using the casting method from As38Se62 glass which features a transmission window from 2 to 10 $\mu m$ and a high nonlinear index of 1.13.10$^{-17}$m$^{2}$W$^{-1}$. It has a zero-dispersion wavelength around 4.5 $\mu m$ and, at this wavelength, a large birefringence of 6.10$^{-4}$ and consequently strong polarization maintaining properties are expected. Using this fiber, we experimentally demonstrate supercontinuum generation spanning from 3.1-6.02 $\mu m$ and 3.33-5.78 $\mu m$ using femtosecond pumping at 4 $\mu m$ and 4.53 $\mu m$, respectively. We further investigate the supercontinuum bandwidth versus the input pump polarization angle and we show very good agreement with numerical simulations of the two-polarization model based on two coupled generalized nonlinear Schr\"odinger equations.Comment: 13 pages, 8 figure

Characterization of Megatrypanum trypanosomes from European Cervidae

Megatrypanum trypanosomes have been isolated from a number of different European Cervidae, but on the basis of morphology it has not been possible to define the species to which these isolates belong. We isolated Trypanosoma (Megatrypanum) theileri from 10 cattle, and Megatrypanum trypanosomes from 11 fallow deer (Cervus dama), 9 red deer (Cervus elaphus), and 4 roe deer (Capreolus capreolus) by blood culture on a biphasic medium (NNN agar slopes). Trypanosomes were propagated in Schneider's Drosophila medium and characterized by isoenzyme analysis and molecular karyotyping. Isocitrate dehydrogenase and phosphoglucomutase were visualized after starch gel electrophoresis of trypanosome lysates. By cluster analysis of this data all isolates from deer were clearly separated from the T. (M.) theileri isolates from cattle. Isolates from roe deer were different not only from T. (M.) theileri but also from the other deer isolates. Isolates from fallow deer and red deer were grouped together. Thus, there are probably at least two different species of Megatrypanum trypanosomes in the three Cervidae. One parasitizing roe deer, the other, apparently less host specific species, infecting red deer and fallow deer. Separation of the chromosomes of Megatrypanum trypanosomes by pulsed-field gradient gel electrophoresis (PFGE) showed that each isolate contained a large number (> 18) of chromosomes ranging in size from 300 to > 2200 kb. The molecular karyotypes were similar for all isolates, although no isolate was identical to anothe