A comprehensive WebCT integration system

Murdoch University, in collaboration with industry partners, has developed a sophisticated middleware application (WebCTMan) between WebCT and other corporate systems, such as the Callista student records system, the Concept 1 human resources system and Murdoch’s own authentication system. This presentation will describe the architecture and functionality of this system. The impetus for WebCTMan was to enable Murdoch to change its student records database with minimal impact on our WebCT installation. However, WebCTMan now gives us great flexibility in managing our WebCT installation, enabling us to manage courses across teaching periods, and upgrade easily. This paper describes the context in which this system was built and gives an overview of its architecture. Courses in WebCTMan can have a status of active (where student details are updated nightly), inactive (where all students are orphans), and static (where student accounts are valid but not updated). Tools are available to change this status, and easily activate and deactivate courses. Different versions of courses are maintained for each teaching period, resolving the problem of overlap between semesters, when some students still have deferred examinations after the start of a new semester. In addition to managing students, WebCTMan provides functionality to manage staff and courses. Staff can request courses to be created or cloned from other courses. They can also create their own guest accounts and allocate tutors and markers to courses, and download class lists. Operators can create or rename courses on demand, as well as changing the roles of staff, including primary and secondary designers. A subset of functions is available to helpdesk operators, who can lookup details of both students and staff within the system

MATCHED ARCHITECTURES FOR SIGNAL PROCESSING AND CONTROL

Fast processing environments for real-time data acquisition, data processing and control applications may be realised using very different architectures. State of the art systems generally employ multiprocessors and parallel processing having a dedicated architecture such as systolic arrays to support computation-intensive signal processing tasks such as, for instance, convolution, filtering, FFT. etc. Mostly, general purpose rather than application driven architectures are used whenever possible and the available literature is heavily concentrated on the first configuration. At TPD-TNO, the research emphasis is on application driven architectures. and the objectives for the so-called 'matched' architecture designs are: - Capability for a wide range of sizes, starting from small systems. The objective here is design for scalability - Design for systems to be used in harsh environments - Design for minimum connectivity. reduced communication bandwidth, incorporation of dedicated preprocessing. multibus systems, etc. The real-time behaviour of general purpose architectures is not sufficiently predictable and they are not designed to perform acquisition tasks or data-intensive processing with high performance. Matched architectures, on the contrary, are designed for well defined applications and optimized for each application, The key effort in matched architecture research is directed towards efficiently mapping algorithms to processing steps in hardware (and software) architectures. Essentially. the design process is iterative

Life events and hemodynamic stress reactivity in the middle-aged and elderly

Recent versions of the reactivity hypothesis, which consider it to be the product of stress exposure and exaggerated haemodynamic reactions to stress that confers cardiovascular disease risk, assume that reactivity is independent of the experience of stressful life events. This assumption was tested in two substantial cohorts, one middle-aged and one elderly. Participants had to indicate from a list of major stressful life events up to six they had experienced in the previous two years. They were also asked to rate how disruptive and stressful they were, at the time of occurrence and now. Blood pressure and pulse rate were measured at rest and in response to acute mental stress. Those who rated the events as highly disruptive at the time of exposure and currently exhibited blunted systolic blood pressure reactions to acute stress. The present results suggest that acute stress reactivity may not be independent of stressful life events experience

Relation between composition and fracture strength in off-stoichiometric metal silicide free-standing membranes

In this work, we investigated the influence of composition on the polycrystalline structure, elastic properties and fracture strength, of ZrxSi1-x, NbxSi1-x, and MoxSi1-x free-standing thin films that were deposited by magnetron sputtering and subsequently annealed at 500 °C. Despite deviations from the stoichiometric composition, the crystalline structure of all films, except for the most Zr-rich ZrxSi1-x, corresponded to their respective stoichiometric disilicide structures, without the formation of a second-phase. Off-stoichiometry was found to be accompanied by the presence of lattice defects and a decrease of the grain size, which bring about a lower tensile stress in the films. The dependence of the fracture strength on the composition was remarkably similar for the three silicides, with the lowest and highest strength values occurring for samples with 30% and 37–40% of metal content, respectively. The observed dependence of strength on composition was attributed to the combination of the Hall-Petch effect, changes in the morphology and strength of grain boundaries, and the enhancement of crystal plasticity due to lattice defects induced by off-stoichiometry

Self-Affirmation Improves Problem-Solving under Stress

High levels of acute and chronic stress are known to impair problem-solving and creativity on a broad range of tasks. Despite this evidence, we know little about protective factors for mitigating the deleterious effects of stress on problem-solving. Building on previous research showing that self-affirmation can buffer stress, we tested whether an experimental manipulation of self-affirmation improves problem-solving performance in chronically stressed participants. Eighty undergraduates indicated their perceived chronic stress over the previous month and were randomly assigned to either a self-affirmation or control condition. They then completed 30 difficult remote associate problem-solving items under time pressure in front of an evaluator. Results showed that self-affirmation improved problem-solving performance in underperforming chronically stressed individuals. This research suggests a novel means for boosting problem-solving under stress and may have important implications for understanding how self-affirmation boosts academic achievement in school settings. © 2013 Creswell et al

Interleukin-33 Contributes Toward Loss of Tolerance by Promoting B-Cell-Activating Factor of the Tumor-Necrosis-Factor Family (BAFF)-Dependent Autoantibody Production

Breaking tolerance is a key event leading to autoimmunity, but the exact mechanisms responsible for this remain uncertain. Here we show that the alarmin IL-33 is able to drive the generation of autoantibodies through induction of the B cell survival factor BAFF. A temporary, short-term increase in IL-33 results in a primary (IgM) response to self-antigens. This transient DNA-specific autoantibody response was dependent on the induction of BAFF. Notably, radiation resistant cells and not myeloid cells, such as neutrophils or dendritic cells were the major source of BAFF and were critical in driving the autoantibody response. Chronic exposure to IL-33 elicited dramatic increases in BAFF levels and resulted in elevated numbers of B and T follicular helper cells as well as germinal center formation. We also observed class-switching from an IgM to an IgG DNA-specific autoantibody response. Collectively, the results provide novel insights into a potential mechanism for breaking immune-tolerance via IL-33-mediated induction of BAFF