532 research outputs found
Following the Mobile Student: Can We Develop the Capacity for a Comprehensive Database to Assess Student Progression?
Presents a study of state-level databases on postsecondary student retention and completion rates and the feasibility of tracking students across state lines. Outlines challenges and recommendations, including establishing a common reporting standard
Nuclear reactor power as applied to a space-based radar mission
The SP-100 Project was established to develop and demonstrate feasibility of a space reactor power system (SRPS) at power levels of 10's of kilowatts to a megawatt. To help determine systems requirements for the SRPS, a mission and spacecraft were examined which utilize this power system for a space-based radar to observe moving objects. Aspects of the mission and spacecraft bearing on the power system were the primary objectives of this study; performance of the radar itself was not within the scope. The study was carried out by the Systems Design Audit Team of the SP-100 Project
Book Reviews
THE SILVERLAKE EXPERIMENT. By Lamar T. Empey and Steven G. Lubeck. Chicago: Aldine Publishing Company, 1971. Pp. x, 354. 10.00.
THE INTERNATIONAL LAW OF CIVIL WAR. Edited by Richard A. Falk. Baltimore: The Johns Hopkins Press, 1971. Pp. xix, 452. 6.95
Navigation input to level C OFT navigation functional subsystem software requirements (rendezvous onorbit-2)
Navigation software design requirements are presented for the orbital flight test phase of space shuttle. Computer loads for the entire onorbit-2 operation are documented
Mars Pathfinder Battery Performance
Contents include the following: (1) mission requirements; (2) battery design features; (3) battery operational overview; (4) battery performance; and (5) summary and conclusions
<dispersion strengthening of metals< summary report, jul. 1963 - jul. 1964
Structure, stability, and properties of dispersion strengthened and internally oxidized alloy
Simulating the Gradually Deteriorating Performance of an RTG
Degra (now in version 3) is a computer program that simulates the performance of a radioisotope thermoelectric generator (RTG) over its lifetime. Degra is provided with a graphical user interface that is used to edit input parameters that describe the initial state of the RTG and the time-varying loads and environment to which it will be exposed. Performance is computed by modeling the flows of heat from the radioactive source and through the thermocouples, also allowing for losses, to determine the temperature drop across the thermocouples. This temperature drop is used to determine the open-circuit voltage, electrical resistance, and thermal conductance of the thermocouples. Output power can then be computed by relating the open-circuit voltage and the electrical resistance of the thermocouples to a specified time-varying load voltage. Degra accounts for the gradual deterioration of performance attributable primarily to decay of the radioactive source and secondarily to gradual deterioration of the thermoelectric material. To provide guidance to an RTG designer, given a minimum of input, Degra computes the dimensions, masses, and thermal conductances of important internal structures as well as the overall external dimensions and total mass
Phenomenology of the Deuteron Electromagnetic Form Factors
A rigorous extraction of the deuteron charge form factors from tensor
polarization data in elastic electron-deuteron scattering, at given values of
the 4-momentum transfer, is presented. Then the world data for elastic
electron-deuteron scattering is used to parameterize, in three different ways,
the three electromagnetic form factors of the deuteron in the 4-momentum
transfer range 0-7 fm^-1. This procedure is made possible with the advent of
recent polarization measurements. The parameterizations allow a
phenomenological characterization of the deuteron electromagnetic structure.
They can be used to remove ambiguities in the form factors extraction from
future polarization data.Comment: 18 pages (LaTeX), 2 figures Feb. 25: minor changes of content and in
Table
Efficacy and safety of enzyme replacement therapy with BMN 110 (elosulfase alfa) for Morquio A syndrome (mucopolysaccharidosis IVA): a phase 3 randomised placebo-controlled study.
ObjectiveTo assess the efficacy and safety of enzyme replacement therapy (ERT) with BMN 110 (elosulfase alfa) in patients with Morquio A syndrome (mucopolysaccharidosis IVA).MethodsPatients with Morquio A aged ≥5 years (N = 176) were randomised (1:1:1) to receive elosulfase alfa 2.0 mg/kg/every other week (qow), elosulfase alfa 2.0 mg/kg/week (weekly) or placebo for 24 weeks in this phase 3, double-blind, randomised study. The primary efficacy measure was 6-min walk test (6MWT) distance. Secondary efficacy measures were 3-min stair climb test (3MSCT) followed by change in urine keratan sulfate (KS). Various exploratory measures included respiratory function tests. Patient safety was also evaluated.ResultsAt week 24, the estimated mean effect on the 6MWT versus placebo was 22.5 m (95 % CI 4.0, 40.9; P = 0.017) for weekly and 0.5 m (95 % CI -17.8, 18.9; P = 0.954) for qow. The estimated mean effect on 3MSCT was 1.1 stairs/min (95 % CI -2.1, 4.4; P = 0.494) for weekly and -0.5 stairs/min (95 % CI -3.7, 2.8; P = 0.778) for qow. Normalised urine KS was reduced at 24 weeks in both regimens. In the weekly dose group, 22.4 % of patients had adverse events leading to an infusion interruption/discontinuation requiring medical intervention (only 1.3 % of all infusions in this group) over 6 months. No adverse events led to permanent treatment discontinuation.ConclusionsElosulfase alfa improved endurance as measured by the 6MWT in the weekly but not qow dose group, did not improve endurance on the 3MSCT, reduced urine KS, and had an acceptable safety profile
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