The Optimization of Oligonucleotide Conjugation Onto Gold Nanoparticles for Biodetection

In this paper we present the optimization procedure for the application of gold nanoparticles as a system for the detection of oligonucleotides. The gold nanoparticles have been conjugated to a pair of 5-alkanethiol-modified 20 base oligonucleotides, designed to align in a tail-to-head manner. Upon hybridization with the complementary target, the plasmon region of the spectra registers a large red-shift, thus forming a reliable colorimetric system for the detection of oligonucleotides.International Semiconductor Conference, 32nd International Semiconductor Conference, Oct 12-14, 2009, Sinaia, Romani

Le Grand écho du Nord de la France

07 novembre 18981898/11/07 (A80,N311).Appartient à l’ensemble documentaire : NordPdeC

Compact lumped elements micromachined band-pass filters with discrete switching for 1.8/5.2 GHz applications

This paper presents the design, fabrication and first experimental results of a dual-band switchable band-pass filter structure for the selection of DCS 1800 and WLAN standards. The design approach makes use of intensive electromagnetic modelling and layout optimisation. The fabrication technology is based on bulk and surface silicon micromachining to manufacture lumped elements on high resistivity silicon bulk and dielectric membrane. Filter test structures were fabricated and their frequency responses are presente

Micromachined filters for 38 and 77 GHz supported on thin membranes

This paper presents the fabrication processes for micromachined millimetre-wave devices, on two different types of semiconductor substrates. The first process uses micromachining on high-resistivity (100) oriented silicon. A three-layer dielectric membrane, with a total thickness of 1.5 um is used as support for the millimetre-wave structures. This process was used for the manufacturing of two coupled line filters, wih central operating frequencies of 38 and 77 GHz, respectively. The second process is based on GaAs micromachining. For the first time, a 2.2 um thin GaAs/AIGaAs membrane, obtained by molecular beam epitaxy growth and micromachining of semi-insulating (100) GaAs, is used as support for millimetre-wave filter structures. Cascaded coplanar waveguide open-end series stubs filter type structures, with central frequences of 38 and 77 GHz, respectively, were designed and manufactured on a GaAs micromachined substrate. 'On wafer' measurements for the filter structures were performed. Losses of less than 1.5 dB at 38 GHz and less than 2 dB at 77 GHz have been obtained for both the silicon as well as for the GaAs-based micromachined filter