87 research outputs found

    Reflection properties of multimode interference devices

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    An Introduction to Sphingolipid Metabolism and Analysis by New Technologies

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    Sphingolipids (SP) are a complex class of molecules found in essentially all eukaryotes and some prokaryotes and viruses where they influence membrane structure, intracellular signaling, and interactions with the extracellular environment. Because of the combinatorial nature of their biosynthesis, there are thousands of SP subspecies varying in the lipid backbones and complex phospho- and glycoheadgroups. Therefore, comprehensive or “sphingolipidomic” analyses (structure-specific, quantitative analyses of all SP, or at least all members of a critical subset) are needed to know which and how much of these subspecies are present in a system as a step toward understanding their functions. Mass spectrometry and related novel techniques are able to quantify a small fraction, but nonetheless a substantial number, of SP and are beginning to provide information about their localization. This review summarizes the basic metabolism of SP and state-of-art mass spectrometric techniques that are producing insights into SP structure, metabolism, functions, and some of the dysfunctions of relevance to neuromedicine

    Acceleration of Hydration of Calcium Silicates by Carbon Dioxide Treatment

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    Injection Sclerotherapy of Bleeding Esophageal Varices: The Henry Ford Hospital Experience

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    An update is provided of our ongoing sclerotherapy experience at Henry Ford Hospital, based on 47 patients who have undergone this procedure. One-month mortality rates for Child\u27s classes C, B, and A were 50%, 22%, and 0%, respectively. Follow-up after one month revealed ten additional mortalities, but none were secondary to esophageal variceal hemorrhage. Strictures secondary to sclerotherapy were amenable to dilation. We advocate sclerotherapy as the treatment of choice for esophageal variceal hemorrhage

    True One Cell Chemical Analysis: A Review

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    The constantly growing field of the true one cell analysis provides important information on the direct chemical composition of various cells and cellular compartments. Since the heterogeneity of individual cells has been established, more researchers are interested in the chemical differences between individual cells and that is the only analysis of the one cell can determine. This results in new technologies and methods being reported regularly. This review highlights the common techniques of micro- and nanomanipulation, Raman spectroscopy, microsocopy, and mass spectrometric imaging as they pertain to the true one cell chemical analysis
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