Comparison of major depression diagnostic classification probability using the SCID, CIDI, and MINI diagnostic interviews among women in pregnancy or postpartum: An individual participant data meta-analysis

Objectives A previous individual participant data meta-analysis (IPDMA) identified differences in major depression classification rates between different diagnostic interviews, controlling for depressive symptoms on the basis of the Patient Health Questionnaire-9. We aimed to determine whether similar results would be seen in a different population, using studies that administered the Edinburgh Postnatal Depression Scale (EPDS) in pregnancy or postpartum. Methods Data accrued for an EPDS diagnostic accuracy IPDMA were analysed. Binomial generalised linear mixed models were fit to compare depression classification odds for the Mini International Neuropsychiatric Interview (MINI), Composite International Diagnostic Interview (CIDI), and Structured Clinical Interview for DSM (SCID), controlling for EPDS scores and participant characteristics. Results Among fully structured interviews, the MINI (15 studies, 2,532 participants, 342 major depression cases) classified depression more often than the CIDI (3 studies, 2,948 participants, 194 major depression cases; adjusted odds ratio [aOR] = 3.72, 95% confidence interval [CI] [1.21, 11.43]). Compared with the semistructured SCID (28 studies, 7,403 participants, 1,027 major depression cases), odds with the CIDI (interaction aOR = 0.88, 95% CI [0.85, 0.92]) and MINI (interaction aOR = 0.95, 95% CI [0.92, 0.99]) increased less as EPDS scores increased. Conclusion Different interviews may not classify major depression equivalently

Bipyridine Adducts of Molybdenum Imido Alkylidene and Imido Alkylidyne Complexes

Seven bipyridine adducts of molybdenum imido alkylidene bispyrrolide complexes of the type Mo(NR)(CHCMe[subscript 2]R′)(Pyr)[subscript 2](bipy) (1a–1g; R = 2,6-i-Pr[subscript 2]C[subscript 6]H[subscript 3] (Ar), adamantyl (Ad), 2,6-Me[subscript 2]C[subscript 6]H[subscript 3] (Ar′), 2-i-PrC[subscript 6]H[subscript 4] (Ar[superscript iPr]), 2-ClC[subscript 6]H[subscript 4] (Ar[superscript Cl]), 2-t-BuC[subscript 6]H[subscript 4] (Ar[superscript tBu]), and 2-MesitylC[subscript 6]H[subscript 4] (Ar[superscript M]), respectively; R′ = Me, Ph) have been prepared using three different methods. Up to three isomers of the adducts are observed that are proposed to be the trans- and two possible cis-pyrrolide isomers of syn-alkylidenes. Sonication of a mixture containing 1a–1g, HMTOH (2,6-dimesitylphenol), and ZnCl[subscript 2](dioxane) led to the formation of MAP species of the type Mo(NR)(CHCMe[subscript 2]R′)(Pyr)(OHMT) (3a–3g). DCMNBD (2,3-dicarbomethoxynorbornadiene) is polymerized employing 3a–3g as initiators to yield >98% cis,syndiotactic poly(DCMNBD). Attempts to prepare bipy adducts of bisdimethylpyrrolide complexes led to the formation of imido alkylidyne complexes of the type Mo(NR)(CCMe[subscript 2]R′)(Me[subscript 2]Pyr)(bipy) (Me[subscript 2]Pyr = 2,5-dimethylpyrrolide; 4a–4g) through a ligand-induced migration of an alkylidene α proton to a dimethylpyrrolide ligand. X-ray structures of Mo(NAr)(CHCMe[subscript 2]Ph)(Pyr)[subscript 2](bipy) (1a), Mo(NAr[superscript iPr])(CHCMe[subscript 2]Ph)(Pyr)(OHMT) (3d), Mo(NAr)(CCMe[subscript 2]Ph)(Me[subscript 2]Pyr)(bipy) (4a), the NAr′ analog of 4a (4c), and Mo(NAr[superscript T])(CCMe[subscript 3])(Me[subscript 2]Pyr)(bipy) (Ar[superscript T] = 2-(2,4,6-i-Pr[subscript 3]C[subscript 6]H[subscript 2])C[subscript 6]H[subscript 4]; 4g) showed normal bond lengths and angles.National Science Foundation (U.S.) (CHE-0841187)National Science Foundation (U.S.) (CHE-1111133)United States. Dept. of Energy (DE-FG02-86ER13564)National Institutes of Health (U.S.) (GM-59426