38 research outputs found

    A Rare Case of Thanatophoric Dysplasia

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    Abstract This case is presented for its rarity in the presentation of this dreaded skeletal dysplasia and it is important to differentiate this skeletal dysplasia from others due to overlapping appearance of features with other dysplasia

    Classification of Acute Myelogenous Leukemia in Blood Microscopic Images Using Supervised Classifier

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    Abstract: Acute Myelogenous Leukemia (AML) is a subtype of acute leukemia that is prevalent among adults. The age of a person with AML is 64 years. The need for automation of leukemia detection arises since current methods involve manual examination of the blood smear as the first step toward diagnosis. It takes lot of time and its accuracy depends on the operator's ability. in proposed system a simple technique that automatically detects and segments AML in blood smears is presented. The proposed method differs from others in: 1) the simplicity of the developed approach; 2) classification of complete blood smear images as opposed to sub images; and 3) The nucleated cells are segmented and detected by the help of this algorithm. Computer simulation involved the following tests: comparing the impact of Hausdorff dimension on the system before and after the influence of local binary pattern digits and then comparing the performance of the proposed algorithms on sub images and full images, and then with some of the existing systems the result of the proposed system will be compared. Eighty microscopic blood images are detected, The current system will managed to obtain 98% accuracy for the localization of the lymphoblast cells and to separate it from the sub images and complete images

    Preliminary phytochemical screening and antimicrobial activity of Samanea saman

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    Samanea saman is a tropically distributed medicinal plant. Antimicrobial activity of aqueous extract of this plant was investigated by Well-diffusion method against three organisms: Escherichia coli, Staphylococcus aureus and Candida albicans. The plant extract showed inhibitory activity against all the tested organisms. Five mg/ml inhibited the growth of E. coli but slightly higher concentration of 10 mg/mL was necessary to show inhibition against S. aureus and C. albicans. Phytochemical screening of the plant revealed the presence of tannins, flavonoides, saponins, steroids, cardiac glycosides and terpenoids. The study scientifically validates the use of plant in traditional medicine

    Analysis of Antibody and Cytokine Markers for Leprosy Nerve Damage and Reactions in the INFIR Cohort in India

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    Leprosy is one of the oldest known diseases. In spite of the established fact that it is least infectious and a completely curable disease, the social stigma associated with it still lingers in many countries and remains a major obstacle to self reporting and early treatment. The nerve damage that occurs in leprosy is the most serious aspect of this disease as nerve damage leads to progressive impairment and disability. It is important to identify markers of nerve damage so that preventive measures can be taken. This prospective cohort study was designed to look at the potential association of some serological markers with reactions and nerve function impairment. Three hundred and three newly diagnosed patients from north India were recruited for this study. The study attempts to reflect a model of nerve damage initiated by mycobacterial antigens and maintained by ongoing inflammation through cytokines such as Tumour Necrosis Factor alpha and perhaps extended by antibodies against nerve components

    © Impact Journals SECURE ROUTING PROTOCOL IN SENSOR NETWORK FOR VAMPIRE ATTACK

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    Ad hoc low-power wireless sensor networks are an exciting research direction in sensing and pervasive computing. Prior security work in this area has focused primarily on denial of communication at the routing or medium access control levels. This paper makes three primary contributions. First, we thoroughly evaluate the vulnerabilities of existing protocols to routing layer battery depletion attacks. We observe that security measures to prevent Vampire attacks are orthogonal to those used to protect routing infrastructure, and so existing secure routing protocols such as Ariadne, SAODV and SEAD do not protect against Vampire attacks. Existing work on secure routing attempts to ensure that adversaries cannot cause path discovery to return an invalid network path, but Vampires do not disrupt or alter discovered paths, instead using existing valid network paths and protocol-compliant messages. Protocols that maximize power efficiency are also inappropriate, since they rely on cooperative node behavior and cannot optimize out malicious action

    Information technology in morbidity management of human lymphatic filariasis—A promising tool in global programme for elimination of lymphatic filariasis

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    Background & objectives: India is a signatory to the 1997 World Health Assembly resolutions on lymphatic fila- riasis, and other neglected tropical diseases, and supports global elimination of lymphatic filariasis by 2020. The global programme to eliminate lymphatic filariasis (GPELF) has two main components, viz. interrupting transmission of LF through mass drug administration; and managing morbidity and preventing disability. Consorted efforts by the Public Health Department in Tamil Nadu state (India) for elimination of LF was launched in the year 1997 concentrating on both the components of the programme. The data on the prevalence of filarial morbidity and its entire management at present is based on manual reports and registers maintained by the field functionaries. To overcome the constraints in the manual reporting, an attempt was made to develop a web-based reporting system with different modules and user-friendly interface. Methods: The Vellore and Thiruvannamalai districts were selected as a study area. The study was conducted between 2011 and 2014, which revealed that the entire morbidity management was based on the manual formats. Constraints in the present manual reporting were analysed. PHP and MySQL tools were used to generate user friendly modules. Feedback was collected from field functionaries at different health centre levels, on the adequacy in the modules and effectiveness of the web-based reporting system. Results: The online reporting modules facilitated data entry at the health subcentre level itself. Analysis and retrieval of data was facilitated at all other levels in the public health system. The modules also covered details of surgical interventions, ex-gratia payments and other benefits extended to the lymphoedema patients by the Government. Interpretation & conclusion: The usage and feedback of the web-based reporting system appeared very encouraging and reliable, indicating that it can be implemented in health programmes for disease management. This web-based user-friendly online reporting system can contribute largely to achieve the goals of the GPELF; specially after MDA is withdrawn

    Wave propagation in a micropolar fluid contained in a visco-elastic membrane

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    The aim of the paper is to investigate the propagation of a pulse in a micropolar fluid contained in a visco-elastic membrane. It was undertaken with a view to study how closely we can approximate the flow of blood in arteries by the above model. We find that for large Reynolds number, the effect of micropolarity is hardly perceptible, whereas for small Reynolds numbers it is of considerable importance

    Elemental analysis of various demineralized tooth graft by EDX-720 XRF: An in vitro study

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    Background: The periodontal regeneration is the most challenging process which involves regeneration of both hard and soft tissues. There are various biomaterials available for this purpose. Tooth graft can be used as a regenerative material in the field of periodontics and implantology. The tooth graft with 70% demineralization is considered to be a better option for periodontal regeneration. Different methods are employed for demineralization of tooth using various acids. Materials and Methods: This study was designed as an in vitro study. Totally 60 teeth were collected and categorized into four groups. Groups I, II, and III teeth were demineralized in 2% nitric acid, 0.6 M hydrochloric acid, and 17% ethylenediaminetetraacetic acid (EDTA), respectively. The Group IV teeth were left undemineralized. The elements present in the various tooth graft groups after demineralization were analyzed by EDX-720 XRF Instrument. Results: The EDTA demineralized tooth graft has higher level of Calcium, Strontium, and Zinc content compared to other tooth graft groups and it was statistically significant with P = 0.001. Conclusion: The EDTA demineralized tooth graft can serve as better graft than 2% nitric acid and 0.6M hydrochloric acid demineralized and undemineralized tooth grafts
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