Stochastic Gradient Deep Multilayer Neural Network based Linear Congruential Generative Cryptosystem for Secured Data Communication in Cloud

Cloud computing is a kind of distributed computing that use a vast network of interconnected resources accessible over the internet.   Security is a crucial concern in cloud computing due to the fact that users save their data on the cloud for convenient access from any location and at any time.   Consequently, many users are worried about safeguarding their sensitive data in an unsafe location.  Therefore, cloud computing architecture requires an innovative cryptographic method that ensures the secrecy, authenticity, integrity, and non-repudiation of data transfer in the cloud.  A new technique called SEMcrypt, which stands for Stochastic Gradient DEep Multilayer Neural Network based Linear Congruential Generative Cryptography, has been developed to enhance secure data transmission. SEMcrypt ensures higher data confidentiality and reduces the time required for communication between the cloud user (i.e., patient) and the server. The SEMcrypt approach has two distinct processes: categorization and secure data transport.  Initially, the data is gathered from the patients and is used as input for the stochastic gradient regularised deep multilayer neural network.   The deep neural network consists of one input layer, two hidden layers, and one output layer.   At first, the information is gathered from the patients and sent to the input layer.   Next, the patient data that has been gathered is examined in hidden layer 1 using the generalised Tikhonov regularisation function.   The patient data that has been analysed is sent to hidden layer 2.   The hyperbolic tangent activation function is used at that layer to classify the patient data.   Subsequently, the categorised data undergoes encryption via the use of Linear Congruential Generative Goldwasser-Micali encryption, ensuring safe transfer of the data.  Subsequently, the encrypted data is sent to the cloud server.   The patient data is encrypted on the server side using the Linear Congruential Generative Goldwasser-Micali decryption technique to prevent unauthorised access or assaults.   Consequently, the authorised recipient receives the unaltered information, which is then kept in the database for further analysis.   Secured data transmission is achieved by ensuring better levels of data confidentiality and reducing the time required for the process.   The experimental assessment focuses on criteria such as the time it takes to generate keys, the level of data confidentiality and integrity, the computing time, and the accuracy of categorization.    The empirical findings demonstrate that our suggested SEMcrypt approach delivers efficient performance outcomes by attaining superior levels of data confidentiality and integrity within a minimal timeframe

Establishing and reporting content validity evidence of Training and Development Capacity Building Scale (TDCBS)

Training and development is a matter of paramount interest to contemporary organisations. The attention given to the subject has given way to a stream of analysis, diagnosis and prescription on the part of organizational scholars, practitioners and popular management writers. But, the closer analysis of the extant training and development literature revealed that focus of the research has been limited to the indivudual phases of the training cycle. A comprehensive instrument, focusing on assessment of all the phases of training cycle has been missing. This gap in the literature provided the impetus to develop the Training and Development Capacity Building Scale (TDCBS). When an instrument is constructed, psychometric testing is needed and the first step is to study content validity. Hence, it was decided to establish and report the content validity evidence for the newly developed scale

Establishing and reporting content validity evidence of Training and Development Capacity Building Scale (TDCBS)

Training and development is a matter of paramount interest to contemporary organisations. The attention given to the subject has given way to a stream of analysis, diagnosis and prescription on the part of organizational scholars, practitioners and popular management writers. But, the closer analysis of the extant training and development literature revealed that focus of the research has been limited to the indivudual phases of the training cycle. A comprehensive instrument, focusing on assessment of all the phases of training cycle has been missing. This gap in the literature provided the impetus to develop the Training and Development Capacity Building Scale (TDCBS). When an instrument is constructed, psychometric testing is needed and the first step is to study content validity. Hence, it was decided to establish and report the content validity evidence for the newly developed scale

A principal components approach to parent-to-newborn body composition associations in South India

Background: size at birth is influenced by environmental factors, like maternal nutrition and parity, and by genes. Birth weight is a composite measure, encompassing bone, fat and lean mass. These may have different determinants. The main purpose of this paper was to use anthropometry and principal components analysis (PCA) to describe maternal and newborn body composition, and associations between them, in an Indian population. We also compared maternal and paternal measurements (body mass index (BMI) and height) as predictors of newborn body composition.Methods: weight, height, head and mid-arm circumferences, skinfold thicknesses and external pelvic diameters were measured at 30 ± 2 weeks gestation in 571 pregnant women attending the antenatal clinic of the Holdsworth Memorial Hospital, Mysore, India. Paternal height and weight were also measured. At birth, detailed neonatal anthropometry was performed. Unrotated and varimax rotated PCA was applied to the maternal and neonatal measurements.Results: rotated PCA reduced maternal measurements to 4 independent components (fat, pelvis, height and muscle) and neonatal measurements to 3 components (trunk+head, fat, and leg length). An SD increase in maternal fat was associated with a 0.16 SD increase (?) in neonatal fat (p < 0.001, adjusted for gestation, maternal parity, newborn sex and socio-economic status). Maternal pelvis, height and (for male babies) muscle predicted neonatal trunk+head (? = 0. 09 SD; p = 0.017, ? = 0.12 SD; p = 0.006 and ? = 0.27 SD; p < 0.001). In the mother-baby and father-baby comparison, maternal BMI predicted neonatal fat (? = 0.20 SD; p < 0.001) and neonatal trunk+head (? = 0.15 SD; p = 0.001). Both maternal (? = 0.12 SD; p = 0.002) and paternal height (? = 0.09 SD; p = 0.030) predicted neonatal trunk+head but the associations became weak and statistically non-significant in multivariate analysis. Only paternal height predicted neonatal leg length (? = 0.15 SD; p = 0.003).Conclusion: principal components analysis is a useful method to describe neonatal body composition and its determinants. Newborn adiposity is related to maternal nutritional status and parity, while newborn length is genetically determined. Further research is needed to understand mechanisms linking maternal pelvic size to fetal growth and the determinants and implications of the components (trunk v leg length) of fetal skeletal growt

AN ASSESSMENT OF POTENTIAL DRUG-DRUG INTERACTIONS IN HYPERTENSIVE PATIENTS IN A TERTIARY CARE HOSPITAL

Objective: To an assessment of potential drug-drug interactions in hypertensive patients in a tertiary care hospital. Methods: A prospective, observational study was conducted at a tertiary care hospital, Erode for a period of 8 mo. A sample of 480 patients was assessed for PDDIs using drug checker in Micromedex®-2.7. Results: A total of 430 patients were analyzed and it was found to be 396 (82.50%) hypertensive patients had PDDIs, and a sum total of 1160 PDDIs were observed. Potential drug-drug interactions (PDDIs) higher in female hypertensive patients [255 (64.39%)] compared to males. Incidences of PDDIs were found to be higher in the age group of 60-70 y were [177 (44.69%)] and incidences of interactions based on the duration of (4-6 d) hospital stays were 272 (68.68%). Moreover, 49.24% of patients were found to be prescribed with more than 7 drugs, with higher incidences of PDDIs. Some of the most common drug interacting pair was between aspirin and clopidogrel combination observed in 325 PDDIs in the major, with pharmacodynamics in nature. Conclusion: Clinical pharmacist ought to have the role of regular monitoring of drug therapy in identifying and preventing the medications that have the potential to cause drug-drug interactions, thereby minimizing the undesirable outcomes in drug medical care and improving the quality of care

EFFECT OF Gliricidia sepium LEAVES EXTRACTS ON Aedes aegypti: LARVICIDAL ACTIVITY

Mosquitoes are the single most important group of insects in terms of public health significance and causing diseases. They are the vectors for the transmission of many viral pathogens and pose serious threat to human health. Chemical insecticides are widely used but they are non-selective and harmful to beneficial organisms. In the present study G. Sepium leaves extracts were used to analyse its effect against Aedes aegypti, to compare the mortality rate while using different solvent extracts of the leaf, to identify the solvent extract which give high rate of larval mortality and to characterise the compounds present in the corresponding leaf extract using phytochemical analysis. The ethanolic extract of G. sepium leaves constitute flavanoids, steroids, glycoside, carbohydrate and saponins compound. Thus it was found to have an inhibitory effect on the growth of larvae than other solvent extracts. In the statistical analysis highest significant difference was observed between 1.5g/l and 2.0g/l concentration of ethanolic extract and other extracts. However no significant difference was observed in other concentrations. The larvicidal activity of the plant extract may be attributed to the presence of active compounds like terpinoids, saponins and steroids

A study to assess the effectiveness of 3% citric acid dressing on diabetic foot ulcer among patients admitted in selected wards of Rajiv Gandhi Government General Hospital, Chennai.

Diabetes mellitus is a common disease all over the world and its prevalence and incidence is steadily increasing.However people with diabetes continue to suffer from the complications of the disease. Foot ulceration is one of the most common formidable complications of diabetes Need for the study Timely resolution of diabetic foot ulceration is essential if further tissue loss and infection are to be avoided. Current guidelines recommend the use of pressure relieving devices, appropriate dressings to promote healing and prevent infection, and where appropriate, debridement, drainage and revascularization. 3% citric acid dressing treatment for diabetic foot ulcer is simple and effective approach. Objectives 1. To assess the pre test wound status score of foot ulcer among diabetic client 2. To assess the effectiveness of 3% citric acid dressing on diabetic foot ulcer among experimental group 3. To compare wound status score among experimental and control group. 4. To associate the post test wound status score with selected demographical and physiological variables among experimental and control group Local application of 3% citric acid dressing can be used as a routine intervention among clients all categorries of wound. An extensive experimental study can be conducted for larger number of samples in tthe health care settings

Comparative evaluation of Platelet Rich Plasma (PRP) + β-Tricalcium Phosphate (β-TCP) and Platelet Rich Fibrin (PRF) + β-Tricalcium Phosphate (β- TCP) on healing of periapical lesions using Cone Beam Computed Tomography (CBCT): An Invivo study

AIM OF THE STUDY: The aim of this study is to quantitatively evaluate and compare bone regeneration in periapical lesions using a combination of Platelet Rich Plasma + β-Tricalcium phosphate and Platelet Rich Fibrin + β –Tricalcium phosphate. MATERIALS AND METHODS: Ten subjects with periapical lesion measuring 10-20 mm in relation to maxillary anteriors indicated for periapical surgery were selected. Pre operative bone density values at periapical region were measured in Hounsefield units using CBCT. Root canal treatment was completed appropriately in all the cases. Under adequate local anesthesia full thickness mucoperiosteal flap was raised, debridement of the periapical lesion followed by root end resection and retrograde filling was done. The 10 subjects were randomly divided into two groups. In Group I, periapical bone defect was filled with PRP + β-TCP and in Group II, with PRF + β-TCP. The mucoperiosteal flaps were repositioned and sutured. Bone density evaluation of the periapical region was done 6 months and 1 year after surgery using CBCT and the HU values were obtained. RESULTS: Mean 6 months HU value obtained for group I and group II were significantly higher than the respective pre op values of both groups. Mean 1 Year HU value obtained for group I and group II were higher than the respective pre op and 6 months HU values. There was no statistically significant difference in bone density HU values between the two groups at 6 Months and 1 year post operatively. CONCLUSION: Both the combinations PRP + β-TCP and PRF + β-TCP are equally effective in promoting bone regeneration and can be considered to be valuable options for placement in periapical bone defects

An overview of multidimensional factors influencing effective performance of expatriates

In the era of rapid globalization, every kind of business and commercial trading calls for a massive exchange of ideas, products, personnel, infrastructure, and development resources across the world. Today\u27s highly competitive global business environment sets the platform for international employee assignments, wherein people possessing the required knowledge base and motivation, move across international boundaries. The purpose of the study is to identify various factors that might influence the expatriates during their foreign assignments. The study gains significance by attempting to understand the cultural challenges and intangible barriers that might exist in a new cultural setting and which might impede the performance of expatriates. The analysis is based on the review of approximately fifty existing papers. The study finally highlights the key factors that make the expatriates perform better in their new working environment

PHARMACIST INTERVENTION ON IDENTIFICATION OF DRUG INTERACTIONS IN TERTIARY CARE HOSPITALS

Objective: The aim of this study was to assess the potential drug interactions (pDIs) among hospitalized patients in cardiac and neurology wards in 3 tertiary care hospitals.Methods: A prospective, observational study was carried out for a period of 12 mo. A sample of 1330 patients was assessed for pDDIs using Micromedex®-2.7and drugs.com and www.dugs.com.Results: A total of 1330 patients were analyzed and it was found that 685 were cardiac and 645 were neurology patients. The study identified 524 (76.49%) cardiac patients and 425 (65.89%) neurology patients, with potential drug-drug interactions (pDDIs) higher in male cardiac [298 (56.87%)] and male neurology [235 (55.29%)] patients, compared to females. Incidences of pDDIs were found to be higher in the age group of 60-70 y in cardiac [193 (36.83%)] and neurology [165 (38.84%)] patients and incidences of interactions based on duration of (4-6 d) hospital stays in cardiac were 380 (72.53%) and 275 (64.70%) in neurology patients respectively. Moreover, 51.90% cardiac patients and 57.41% neurology patients were found to be prescribed with more number of drugs in cardiac and neurology (7 drugs) patients, were found to have developed higher incidences of pDDIs. The most common drug interacting pair was between aspirin and clopidogrel combination, observed in 245 cardiac and 316 in neurology patients. Drug-food interactions (DFIs) were found with between atorvastatin-citrus fruits in cardiac and phenytoin-protein rich foods in neurology patients. The most common drug-disease interaction (D-DIs) was found to between isosorbide dinitrate–myocardial infarction in cardiac and carbamazepine-seizuresin neurology respectively.Conclusion: It is recommended that physicians should be aware of the interactions among those drugs while prescribing, and careful monitoring is also required