Tunable Graphene Antennas for Selective Enhancement of THz-Emission

In this paper, we will introduce THz graphene antennas that strongly enhance the emission rate of quantum systems at specific frequencies. The tunability of these antennas can be used to selectively enhance individual spectral features. We will show as an example that any weak transition in the spectrum of coronene can become the dominant contribution. This selective and tunable enhancement establishes a new class of graphene-based THz devices, which will find applications in sensors, novel light sources, spectroscopy, and quantum communication devices

On the black hole limit of rotating discs and rings

Solutions to Einstein's field equations describing rotating fluid bodies in equilibrium permit parametric (i.e. quasi-stationary) transitions to the extreme Kerr solution (outside the horizon). This has been shown analytically for discs of dust and numerically for ring solutions with various equations of state. From the exterior point of view, this transition can be interpreted as a (quasi) black hole limit. All gravitational multipole moments assume precisely the values of an extremal Kerr black hole in the limit. In the present paper, the way in which the black hole limit is approached is investigated in more detail by means of a parametric Taylor series expansion of the exact solution describing a rigidly rotating disc of dust. Combined with numerical calculations for ring solutions our results indicate an interesting universal behaviour of the multipole moments near the black hole limit.Comment: 18 pages, 4 figures; Dedicated to Gernot Neugebauer on the occasion of his 70th birthda

Kick stability in groups and dynamical systems

We consider a general construction of ``kicked systems''. Let G be a group of measure preserving transformations of a probability space. Given its one-parameter/cyclic subgroup (the flow), and any sequence of elements (the kicks) we define the kicked dynamics on the space by alternately flowing with given period, then applying a kick. Our main finding is the following stability phenomenon: the kicked system often inherits recurrence properties of the original flow. We present three main examples. 1) G is the torus. We show that for generic linear flows, and any sequence of kicks, the trajectories of the kicked system are uniformly distributed for almost all periods. 2) G is a discrete subgroup of PSL(2,R) acting on the unit tangent bundle of a Riemann surface. The flow is generated by a single element of G, and we take any bounded sequence of elements of G as our kicks. We prove that the kicked system is mixing for all sufficiently large periods if and only if the generator is of infinite order and is not conjugate to its inverse in G. 3) G is the group of Hamiltonian diffeomorphisms of a closed symplectic manifold. We assume that the flow is rapidly growing in the sense of Hofer's norm, and the kicks are bounded. We prove that for a positive proportion of the periods the kicked system inherits a kind of energy conservation law and is thus superrecurrent. We use tools of geometric group theory and symplectic topology.Comment: Latex, 40 pages, revised versio

Case Reports1. A Late Presentation of Loeys-Dietz Syndrome: Beware of TGFβ Receptor Mutations in Benign Joint Hypermobility

Background: Thoracic aortic aneurysms (TAA) and dissections are not uncommon causes of sudden death in young adults. Loeys-Dietz syndrome (LDS) is a rare, recently described, autosomal dominant, connective tissue disease characterized by aggressive arterial aneurysms, resulting from mutations in the transforming growth factor beta (TGFβ) receptor genes TGFBR1 and TGFBR2. Mean age at death is 26.1 years, most often due to aortic dissection. We report an unusually late presentation of LDS, diagnosed following elective surgery in a female with a long history of joint hypermobility. Methods: A 51-year-old Caucasian lady complained of chest pain and headache following a dural leak from spinal anaesthesia for an elective ankle arthroscopy. CT scan and echocardiography demonstrated a dilated aortic root and significant aortic regurgitation. MRA demonstrated aortic tortuosity, an infrarenal aortic aneurysm and aneurysms in the left renal and right internal mammary arteries. She underwent aortic root repair and aortic valve replacement. She had a background of long-standing joint pains secondary to hypermobility, easy bruising, unusual fracture susceptibility and mild bronchiectasis. She had one healthy child age 32, after which she suffered a uterine prolapse. Examination revealed mild Marfanoid features. Uvula, skin and ophthalmological examination was normal. Results: Fibrillin-1 testing for Marfan syndrome (MFS) was negative. Detection of a c.1270G > C (p.Gly424Arg) TGFBR2 mutation confirmed the diagnosis of LDS. Losartan was started for vascular protection. Conclusions: LDS is a severe inherited vasculopathy that usually presents in childhood. It is characterized by aortic root dilatation and ascending aneurysms. There is a higher risk of aortic dissection compared with MFS. Clinical features overlap with MFS and Ehlers Danlos syndrome Type IV, but differentiating dysmorphogenic features include ocular hypertelorism, bifid uvula and cleft palate. Echocardiography and MRA or CT scanning from head to pelvis is recommended to establish the extent of vascular involvement. Management involves early surgical intervention, including early valve-sparing aortic root replacement, genetic counselling and close monitoring in pregnancy. Despite being caused by loss of function mutations in either TGFβ receptor, paradoxical activation of TGFβ signalling is seen, suggesting that TGFβ antagonism may confer disease modifying effects similar to those observed in MFS. TGFβ antagonism can be achieved with angiotensin antagonists, such as Losartan, which is able to delay aortic aneurysm development in preclinical models and in patients with MFS. Our case emphasizes the importance of timely recognition of vasculopathy syndromes in patients with hypermobility and the need for early surgical intervention. It also highlights their heterogeneity and the potential for late presentation. Disclosures: The authors have declared no conflicts of interes

A Brief Measure of Staff Commitment to Implement School-Wide Positive Behavioral Interventions and Supports

Staff buy-in has been implicated as an important factor in the implementation of school-wide positive behavioral interventions and supports (SW-PBIS). However, most evidence related to buy-in is indirect and does not involve systematic measurement of buy-in. The purpose of the present study was to develop and evaluate a six-item measure of staff commitment to implement SW-PBIS. Responses were gathered from 1,218 teachers and staff working in schools at various stages of SW-PBIS implementation. Results showed strong evidence of internal consistency, construct validity, and content validity for the buy-in measure. There was a strong bias toward positive responding on the measure, but there were statistically significant differences that aligned with previous research (e.g., grade level of the school, role of respondents). In terms of concurrent validity, the relation between commitment and fidelity of implementation was as hypothesized, but the low number of schools and limited variability made the findings tentative

Stability of hepatitis E virus at high hydrostatic pressure processing

Hepatitis E virus (HEV) is the causative agent of acute and chronic hepatitis in humans. The zoonotic HEV genotype 3 is the main genotype in Europe. The foodborne transmission via consumption of meat and meat products prepared from infected pigs or wild boars is considered the major transmission route of this genotype. High hydrostatic pressure processing (HPP) is a technique, which can be used for inactivation of pathogens in food. Here, preparations of a cell culture-adapted HEV genotype 3 strain in phosphate-buffered saline (PBS) were subjected to HPP and the remaining infectivity was titrated in cell culture by counting fluorescent foci of replicating virus. A gradual decrease in infectivity was found by application of 100 to 600 MPa for 2 min. At 20 °C, infectivity reduction of 0.5 log10 at 200 MPa and 1 log10 at 400 MPa were observed. Slightly higher infectivity reduction of 1 log10 at 200 MPa and 2 log10 at 400 MPa were found by application of the pressure at 4 °C. At both temperatures, the virus was nearly completely inactivated (>3.5 log10 infectivity decrease) at 600 MPa; however, low amounts of remaining infectious virus were observed in one of three replicates in both cases. Transmission electron microscopy showed disassembled and distorted particles in the preparations treated with 600 MPa. Time-course experiments at 400 MPa showed a continuous decline of infectivity from 30 s to 10 min, leading to a 2 log10 infectivity decrease at 20 °C and to a 2.5 log10 infectivity decrease at 4 °C for a 10 min pressure application each. Predictive models for inactivation of HEV by HPP were generated on the basis of the generated data. The results show that HPP treatment can reduce HEV infectivity, which is mainly dependent on pressure height and duration of the HPP treatment. Compared to other viruses, HEV appears to be relatively stable against HPP and high pressure/long time combinations have to be applied for significant reduction of infectivity

Design and characterization of microscale heater structures for test die and sensor applications

The authors describe a class of microscale heaters fabricated with CMOS processes on silicon wafers. These heaters were designed to produce localized high temperatures above 400 C for test and sensor applications. The temperature levels produced for various input powers and the thermal profiles surrounding the heater for packaged and wafer-level heater structures were studied to guide the placement of microelectronics integrated with the heater structures on the same die. To show the performance of the design, they present resistance sensor measurements, IR temperature profiles, and results from a 3D thermal model of the die. This effort demonstrates that it is possible to successfully operate both a microscale heater and microcircuits on the same die