An Empirical Analysis of Backpropagation Error Surface Initiation for Injection Molding Process Control

Backpropagation neural networks are trained by adjusting initially random interconnecting weights according to the steepest local error surface gradient. The authors examine the practical implications of the arbitrary starting point on the error landscape of the ensuing trained network. The effects on network convergence and performance are tested empirically, varying parameters such as network size, training rate, transfer function and data representation. The data used are live process control data from an injection molding plan

Human resource strategies of Chinese state crewing agencies with special reference to labour export and the experience of Chinese seafarers

The Chinese shipping industry is one of the fastest developing sectors in the Chinese economy. However, few studies have explored the changes within it, especially concerning its human resource element - seafarers - and the newly formed crewing agencies through which they are employed. This research seeks to explore the contemporary experience of Chinese seafarers and especially how this is impacted by the management strategies of Chinese crewing agencies. In doing so, it contributes to debates about changes in Chinese society - that is, whether the economic reform has led to a new market economy in China. The idea of the emergence of a modernized, free Chinese seafarer labour market is critically examined through research into the employment and labour supply strategies of two ship crewing agencies, which have been reformed to different degrees, and the experience of the seafarers who work for them. The research utilises qualitative methods, with twenty-two managers and fifty seafarers being interviewed extensively, supplemented by documentary research. It seeks to explain why China's seafaring labour export is far lower than people have expected. It is seen that it is difficult to characterise China's seafarer labour market as a free market. The state has limited the liberalization of the market by granting foreign manning qualification to less than sixty state-owned crewing agencies. It is seen that institutions at higher levels still intervene in the operation of the agencies, with their management consequently showing a lack of market orientation to different extents, which constrains the development of China's labour export. It is also difficult to characterise the movement of Chinese seafarers in the labour market as free movement. The argument that Chinese economic reform leads to the transformation of Chinese seafarers into freelancers, which implies a substantial increase of seafarer export due to the attractiveness of working in foreign shipping companies, is too simplistic. In addition, the wages of Chinese seafarers working in the global labour market are lower than the international benchmark rates and are not necessarily higher than the payments by domestic shipping companies. This weakens the willingness of Chinese seafarers to work in foreign shipping companies.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Oral health and related factors in a group of children with cystic fibrosis in Istanbul, Turkey

Background: Cystic fibrosis (CF) patients can be considered as high caries risk patients because they frequently consume sugar.rich food between meals and they have a high intake of sugar containing syrups, aerosols, and salivary flow reducing medication. Variable caries prevalences were reported in CF patients in previous studies. There are no studies related to CF and salivary thromboplastic activity, which can be presented as a marker of wound healing and bleeding tendency of oral cavity.Objective: The aim of this study was to compare oral health status and salivary pH, flow rate, and thromboplastic activity in children with CF and healthy controls.Materials and Methods: Asample of 35 children with CF (23 girls and 12 boys), and 12 healthy control subjects (6 girls and 6 boys) were selected. Caries experience, oral hygiene, and dental erosion were assessed. Salivary flow rate, pH, thromboplastic activity, and total protein content were determined. Differences between the groups were evaluated using Chi.square test with a significance level set at 0.05.Results: The differences between children with CF and healthy controls in tooth brushing frequency, use of fluoride tablets, caries experience, dental erosion index, oral hygiene index, salivary flow rate and total protein levels were not statistically significant (P > 0.05). Salivary thromboplastic activity of the CF group was significantly lower than the healthy controls (P < 0.01).Conclusion: Large population studies may be necessary to establish the role of salivary thromboplastic activity in children with CF considering our findings related to the decreased salivary thromboplastic activity, which  may indicate delayed oral wound healing process.Key words: Caries, children, cystic fibrosis, saliva, salivary thromboplastic activit

Collagenous Fibroma (Desmoplastic Fibroblastoma) of the Neck Presenting with Neurological Symptoms

Collagenous fibromas are rare fibrous soft tissue tumours that usually arise in subcutaneous tissue or skeletal muscle at a variety of anatomical sites. These lesions commonly present as painless, slow-growing mobile masses. We describe a unique case of a 41-year-old woman presenting with a posterior neck swelling and longstanding history of severe ongoing pain in the right scapular region, shoulder and neck, weakness of the palmar grip and limited right lateral neck flexion and rotation. A history of trauma to the right neck in adolescence was noted. Histological analysis revealed a paucicellular lesion with spindle and stellate-shaped fibroblasts involving the cervical nerve roots, typical of collagenous fibroma. In a literature search on Medline and Pubmed, we found no reported cases of collagenous fibromas presenting with neurological symptoms. This report highlights the potential of these lesions to present with neurological symptoms due to infiltration of surrounding tissues, and that preceding trauma may contribute to the aetiology

Prenatal treatment path for angelman syndrome and other neurodevelopmental disorders

Angelman syndrome (AS) is a rare neurodevelopmental disorder caused by mutation or deletion of the maternally inherited UBE3A allele. These pathogenic mutations lead to loss of maternal UBE3A expression in neurons. Antisense oligonucleotides and gene therapies are in development, which activate the intact but epigenetically silenced paternal UBE3A allele. Preclinical studies indicate that treating during the prenatal period could greatly reduce the severity of symptoms or prevent AS from developing. Genetic tests can detect the chromosome 15q11-q13 deletion that is the most common cause of AS. New, highly sensitive noninvasive prenatal tests that take advantage of single-cell genome sequencing technologies are expected to enter the clinic in the coming years and make early genetic diagnosis of AS more common. Efforts are needed to identify fetuses and newborns with maternal 15q11-q13 deletions and to phenotype these babies relative to neurotypical controls. Clinical and parent observations suggest AS symptoms are detectable in infants, including reports of problems with feeding and motor function. Quantitative phenotypes in the 0- to 1-year age range will permit a more rapid assessment of efficacy when future treatments are administered prenatally or shortly after birth. Although prenatal therapies are currently not available for AS, prenatal testing combined with prenatal treatment has the potential to revolutionize how clinicians detect and treat babies before they are symptomatic. This pioneering prenatal treatment path for AS will lay the foundation for treating other syndromic neurodevelopmental disorders. Autism Res 2020, 13: 11–17. © 2019 International Society for Autism Research, Wiley Periodicals, Inc. Lay summary: Prenatal treatment could benefit expectant parents whose babies test positive for the chromosome microdeletion that causes Angelman syndrome (AS). Prenatal treatment is predicted to have better outcomes than treating after symptoms develop and may even prevent AS altogether. This approach could generally be applied to the treatment of other syndromic neurodevelopmental disorders

Peritonite bacteriana espontânea associado a cirrose hepática. Relato de caso

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Optics and Quantum Electronics

Contains reports on ten research projects.Joint Services Electronics Program (Contract DAALO3-86-K-0002)National Science Foundation (Grant ECS 83-05448)National Science Foundation (Grant ECS 83-10718)National Science Foundation (Grant ECS 82-11650)National Science Foundation (Grant ECS 84-13178)National Science Foundation (Grant ECS 85-52701)US Air Force - Office of Scientific Research (Contract AFOSR-85-0213)National Institutes of Health (Contract 5-RO1-GM35459)U.S. Navy - Office of Naval Research (Contract N00014-86-K-0117

Aspectos ultra-sonográficas modo B, Doppler colorido e Power doppler no carcinoma de células transicionais da bexiga de cães. Estudo de casos

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