5 research outputs found

    Measurement of insulin and other glucose-regulating peptide hormones.

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    Insulin activity is an important laboratory parameter in the clinical evaluation of several diseases such as diabetes mellitus types I and II, states of impaired glucose tolerance, and insulin-producing tumors (insulinomas), where the insulin secretion released from pancreas β-cells is altered

    Measurement of blood glucose-lowering and antidiabetic activity.

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    The rabbit has been used since many years for standardization of insulin (see K.4.1). Therefore, it has been chosen as the primary screening model for screening of blood glucose-lowering compounds as well as for establishing time-response curves and relative activities (Bänder et al. 1969, Geisen 1988)
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