5 research outputs found
Severe Hypoglycemia and Hypokalemia in Association with Liver Metastases of Gastric Cancer
Minimally Invasive Monitoring of Chronic Central Venous Catheter Patency in Mice Using Digital Subtraction Angiography (DSA)
Measurement of insulin and other glucose-regulating peptide hormones.
Insulin activity is an important laboratory parameter in the clinical evaluation of several diseases such as diabetes mellitus types I and II, states of impaired glucose tolerance, and insulin-producing tumors (insulinomas), where the insulin secretion released from pancreas β-cells is altered
Measurement of blood glucose-lowering and antidiabetic activity.
The rabbit has been used since many years for standardization of insulin (see K.4.1). Therefore, it has been chosen as the primary screening model for screening of blood glucose-lowering compounds as well as for establishing time-response curves and relative activities (Bänder et al. 1969, Geisen 1988)