Use of accelerometry to investigate physical activity in dogs receiving chemotherapy

Objectives: To perform a preliminary study to assess whether single-agent palliative or adjuvant chemotherapy has an impact on objectively measured physical activity in dogs. Methods: Fifteen dogs with neoplasia (treatment group) wore ActiGraph™ accelerometers for 5-day periods before, during and after receiving single-agent adjuvant or palliative chemotherapy. Mean 5-day total physical activity and time spent in three different intensities of activity (sedentary, light-moderate and vigorous) before, during and after receiving chemotherapy were compared to a group of 15 healthy dogs (control group). Results were also compared within the treatment group across time. Results: Prior to chemotherapy, treated dogs tended to be less active than control dogs. Treatment group dogs were slightly more active at restaging than they were prior to treatment but had similar activity levels to control dogs. Marked effects of chemotherapy on physical activity were not detected. Physical activity was slightly lower in treated dogs during chemotherapy when compared to control dogs but there was a slight increase in physical activity of treated dogs during chemotherapy when compared with pretreatment recordings. There was little change in the mean 5-day total physical activity between treated dogs during chemotherapy and at restaging but a mild decrease in time spent sedentary and increase in time spent in light-moderate activity at this comparison of time points. Clinical Significance: Single-agent adjuvant or palliative chemotherapy had minimal impact on physical activity levels in dogs with neoplasia

A Catalyst for Urban Renewal: Reservoir Number Three Environmental History Museum

This architectural thesis investigates how architecture can have an impact on urban renewal by strengthening communities with an architecture which promotes human interaction through spatial and programmatic interconnections, as well as promoting relationships between people, their history, and context

Accretion and activity on the post-common-envelope binary RR~Cae

Current scenarios for the evolution of interacting close binaries - such as cataclysmic variables (CVs) - rely mainly on our understanding of low-mass star angular momentum loss (AML) mechanisms. The coupling of stellar wind with its magnetic field, i.e., magnetic braking, is the most promising mechanism to drive AML in these stars. There are basically two properties driving magnetic braking: the stellar magnetic field and the stellar wind. Understanding the mechanisms that drive AML therefore requires a comprehensive understanding of these two properties. RRCae is a well-known nearby (d=20pc) eclipsing DA+M binary with an orbital period of P=7.29h. The system harbors a metal-rich cool white dwarf (WD) and a highly active M-dwarf locked in synchronous rotation. The metallicity of the WD suggests that wind accretion is taking place, which provides a good opportunity to obtain the mass-loss rate of the M-dwarf component. We analyzed multi-epoch time-resolved high-resolution spectra of RRCae in search for traces of magnetic activity and accretion. We selected a number of well-known activity indicators and studied their short and long-term behavior. Indirect-imaging tomographic techniques were also applied to provide the surface brightness distribution of the magnetically active M-dwarf, and reveals a polar feature similar to those observed in fast-rotating solar-type stars. The blue part of the spectrum was modeled using a atmosphere model to constrain the WD properties and its metal enrichment. The latter was used to improve the determination of the mass-accretion rate from the M-dwarf wind. The presence of metals in the WD spectrum suggests that this component arises from accretion of the M-dwarf wind. A model fit to the WD gives Teff=(7260+/-250)K and logg=(7.8+/-0.1) dex with a metallicity of =(-2.8+/-0.1)dex, and a mass-accretion rate of dotMacc=(7+/-2)x1e-16Msun/yr.Comment: 14 pages, 7 Figures, 6 Table

Studies of hot B subdwarfs. Part 2: Energy distributions of three bright sdB/sdOB stars in the 950-5500 angstrom range

Voyager ultraviolet spectrometer observations of the subdwarf B or OB stars HD 205805, UV 1758+36 and Feige 66 are presented. All three objects display the H I Layman series in absorption. These observations are combined with low dispersion IUE spectrophotometry and with Stroemgren photometry to construct virtually complete energy distributions, which extend over the range 950-5500 angstroms. Effective temperatures based on model atmosphere calculations for high gravity, hydrogen rich stars are determined. Our analyses yield T Sub e 28,200 + or - 1300 K for HD 205805, T sub e 31, 800 + or - 1100 K for UV 1758+36, and T sub e 35,700 + or - 1500 K for Feige 66. The importance of far ultraviolet observations below L sub alpha in reducing the uncertainties associated with the interstellar extinction and the degradation of the IUE sensitivity is emphasized

Studies of the use of high-temperature nuclear heat from an HTGR for hydrogen production

The results of a study which surveyed various methods of hydrogen production using nuclear and fossil energy are presented. A description of these methods is provided, and efficiencies are calculated for each case. The process designs of systems that utilize the heat from a general atomic high temperature gas cooled reactor with a steam methane reformer and feed the reformer with substitute natural gas manufactured from coal, using reforming temperatures, are presented. The capital costs for these systems and the resultant hydrogen production price for these cases are discussed along with a research and development program

Mantle flow beneath La Réunion hotspot track from SKS splitting

International audienceIf upper mantle anisotropy beneath fast-moving oceanic plates is expected to align the fast azimuths close to the plate motion directions, the upper mantle flow pattern beneath slow-moving oceanic plates will reflect the relative motion between the moving plate and the underlying large-scale convecting mantle. In addition to the non-correlation of the fast azimuths with the plate motion direction, the flow and anisotropy pattern may be locally perturbed by other factors such as the upwelling and the sublithospheric spreading of mantle plumes. Investigating such plume–lithosphere interaction is strongly dependent on the available seismological data, which are generally sparse in oceanic environment. In this study, we take the opportunity of recent temporary deployments of 15 seismic stations and 5 permanent stations on the Piton de la Fournaise volcano, the active locus of La Ré union hotspot and of 6 permanent stations installed along or close to its fossil track of about 3700 km in length, to analyze azimuthal anisotropy detected by SKS wave splitting and to decipher the various possible origins of anisotropy beneath the Western Indian Ocean. From about 150 good and fair splitting measurements and more than 1000 null splitting measurements, we attempt to distinguish between the influence of a local plume signature and large-scale mantle flow. The large-scale anisotropy pattern obtained at the SW-Indian Ocean island stations is well explained by plate motion relative to the deep mantle circulation. By contrast, stations on La Ré union Island show a complex signature characterized by numerous ''nulls'' and by fast split shear wave polarizations trending normal to the plate motion direction and obtained within a small backazimuthal window, that cannot be explained by either a single or two anisotropic layers. Despite the sparse spatial coverage which precludes a unique answer, we show that such pattern may be compatible with a simple model of sublithospheric spreading of La Ré union plume characterized by a conduit located at 100–200 km north of La Ré union Island. Anisotropy beneath the new GEOSCOPE station in Rodrigues Island does not appear to be influenced by La Ré union plume-spreading signature but is fully compatible with either a model of large-scale deep mantle convection pattern and/or with a channeled asthenospheric flow beneath the Rodrigues ridge.

One Dimensional Oxygen Ordering in YBa2Cu3O(7-delta)

A model consisting of oxygen-occupied and -vacant chains is considered, with repulsive first and second nearest-neighbor interactions V1 and V2, respectively. The statistical mechanics and the diffraction spectrum of the model is solved exactly and analytically with the only assumption V1 >> V2. At temperatures T ~ V1 only a broad maximum at (1/2,0,0) is present, while for ABS(delta - 1/2) > 1/14 at low enough T, the peak splits into two. The simple expression for the diffraction intensity obtained for T << V1 represents in a more compact form previous results of Khachaturyan and Morris[1],extends them to all delta and T/V2 and leads to a good agreement with experiment. [1] A.G.Khachaturyan and J.W.Morris, Jr., Phys.Rev.Lett. 64,76(1990)Comment: 13 pages,Revtex,3 figures available upon request but can be plotted using simple analytical functions,CNEA-CAB 92/04