3,386 research outputs found
Low temperature study of field induced antiferro-ferromagnetic transition in Pd doped FeRh
The first order antiferromagnetic (AFM) to ferromagnetic (FM) transition in
the functional material Fe49(Rh0.93Pd0.07)51 has been studied at low
temperatures and high magnetic fields. We have addressed the non-monotonic
variation of lower critical field required for FM to AFM transition. It is
shown that critically slow dynamics of the transition dominates below 50 K. At
low temperature and high magnetic field, state of the system depends on the
measurement history resulting in tunable coexistence of AFM and FM phases. By
following cooling and heating in unequal magnetic field (CHUF) protocol it is
shown that equilibrium state at 6 Tesla magnetic field is AFM state. Glass like
FM state at 6 T (obtained after cooling in 8 T) shows reentrant transition with
increasing temperature; viz. devitrification to AFM state followed by melting
to FM state.Comment: 8 pages, 7 figure
Uterine Perforation With Subtotal Small Bowel Prolapse – A Rare Complication of Dilatation and Curettage
Uterine perforation is the well known complication of induced abortion. We report a rare case of uterine perforation with subtotal prolapse of small bowel following first trimester abortion by an unqualified physician. Early surgical exploration with resection and anastomosis of bowel performed. Patient discharged uneventfully after postoperative recovery
Towards development of a fully synthetic conjugate vaccine: Investigation of structural analogs of \u3ci\u3eStreptococcus pneumoniae \u3c/i\u3e serogroup 6
Involvement of complex glycostructures in a variety of damaging and healing processes has already been acknowledged by development of carbohydrate-based vaccines and therapeutics. The bacteria Streptococcus pneumoniae (SPn) have become one of the most frequent causes of pneumonia, bacteremia, and meningitis in the elderly, immunocompromised, and, especially, in young children. SPn has one of the largest public health and economic impacts amongst all bacterial infectious diseases. Over 2 million children die annually worldwide due to pneumonia, accounting for almost 20% of deaths under age five with more than half of these deaths attributed to SPn. Amongst over ninety elucidated SPn serotypes, the SPn serogroup6 has been consistently ranked within the top three causes of invasive pneumococcal disease worldwide. The SPn bacterial cell is surrounded by a polysaccharide capsule and preventive vaccination is a viable tool against the bacterial invasion. Usually, serotype-specific antibodies are formed in response. Synthetic oligosaccharide components can be conjugated to a carrier protein with conventional coupling chemistry, to obtain semi-synthetic conjugate vaccines (glycoconjugates). This doctoral dissertation describes the application of a new glycosylation method for the synthesis of glycostructures to study immunological properties of serogroup 6. The development of an expeditious strategy to obtain synthetic saccharides of SPn6 and glycoconjugates thereof will ensure reliable and reproducible immunological studies. Consequently, by identifying the immunogenic responses of these glycoconjugates, will help target toward the development of effective vaccine candidates against SPn
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