The association of corticosteroid therapy and the outcome of critically ill patients with the Middle East Respiratory Syndrome

Systematic corticosteroids are commonly used among critically ill patients with the Middle East Respiratory Syndrome (MERS), but their impact on outcome is uncertain. Studies that adjust only for baseline characteristics do not account for the clinical condition at the time of corticosteroid initiation. The objective of this study is to investigate the association of corticosteroids on mortality accounting for time-dependent variables during critical illness up-to the time of corticosteroid initiation

Effect of ribavirin and interferon on the outcome of critically ill patients with mers

Interferon and ribavirin have been used in the treatment of the Middle East Respiratory Syndrome (MERS), but the efficacy of this therapy remains uncertain. Existing data are limited by the lack of adjustment to time-dependent covariates at the time of initiation of therapy. This study objective is to examine the association of ribavirin/interferon in critically ill MERS patients using marginal structural models

The association of corticosteroid therapy and the outcome of critically ill patients with the Middle East Respiratory Syndrome

Systematic corticosteroids are commonly used among critically ill patients with the Middle East Respiratory Syndrome (MERS), but their impact on outcome is uncertain. Studies that adjust only for baseline characteristics do not account for the clinical condition at the time of corticosteroid initiation. The objective of this study is to investigate the association of corticosteroids on mortality accounting for time-dependent variables during critical illness up-to the time of corticosteroid initiation