839 research outputs found
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Copia digital : Diputación Provincial de Zaragoza. Servicio de Archivos y Bibliotecas, 201
Evolution of density perturbations in double exponential quintessence models
In this work we investigate the evolution of matter density perturbations for
quintessence models with a self-interaction potential that is a combination of
exponentials. One of the models is based on the Einstein theory of gravity,
while the other is based on the Brans-Dicke scalar tensor theory. We constrain
the parameter space of the models using the determinations for the growth rate
of perturbations derived from data of the 2-degree Field Galaxy Redshift
Survey.Comment: 5 pages, 3 eps figure
Dual geometries and spacetime singularities
The notion of geometrical duality is discussed in the context of both
Brans-Dicke theory and general relativity. It is shown that, in some particular
solutions, the spacetime singularities that arise in usual Riemannian general
relativity may be avoided in its dual representation (Weyl-type general
relativity). This dual representation provides a singularity-free picture of
the World that is physicaly equivalent to the canonical general relativistic
one.Comment: 11 pages, LaTeX, no figures, version accepted for publication in PR
Reconstruction of a Nonminimal Coupling Theory with Scale-invariant Power Spectrum
A nonminimal coupling single scalar field theory, when transformed from
Jordan frame to Einstein frame, can act like a minimal coupling one. Making use
of this property, we investigate how a nonminimal coupling theory with
scale-invariant power spectrum could be reconstructed from its minimal coupling
counterpart, which can be applied in the early universe. Thanks to the coupling
to gravity, the equation of state of our universe for a scale-invariant power
spectrum can be relaxed, and the relation between the parameters in the action
can be obtained. This approach also provides a means to address the Big-Bang
puzzles and anisotropy problem in the nonminimal coupling model within Jordan
frame. Due to the equivalence between the two frames, one may be able to find
models that are free of the horizon, flatness, singularity as well as
anisotropy problems.Comment: 31 pages, 4 figure
Combinations of β-lactam or aminoglycoside antibiotics with plectasin are synergistic against methicillin-sensitive and methicillin-resistant Staphylococcus aureus.
Bacterial infections remain the leading killer worldwide which is worsened by the continuous emergence of antibiotic resistance. In particular, methicillin-sensitive (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) are prevalent and the latter can be difficult to treat. The traditional strategy of novel therapeutic drug development inevitably leads to emergence of resistant strains, rendering the new drugs ineffective. Therefore, rejuvenating the therapeutic potentials of existing antibiotics offers an attractive novel strategy. Plectasin, a defensin antimicrobial peptide, potentiates the activities of other antibiotics such as β-lactams, aminoglycosides and glycopeptides against MSSA and MRSA. We performed in vitro and in vivo investigations to test against genetically diverse clinical isolates of MSSA (n = 101) and MRSA (n = 115). Minimum inhibitory concentrations (MIC) were determined by the broth microdilution method. The effects of combining plectasin with β-lactams, aminoglycosides and glycopeptides were examined using the chequerboard method and time kill curves. A murine neutropenic thigh model and a murine peritoneal infection model were used to test the effect of combination in vivo. Determined by factional inhibitory concentration index (FICI), plectasin in combination with aminoglycosides (gentamicin, neomycin or amikacin) displayed synergistic effects in 76-78% of MSSA and MRSA. A similar synergistic response was observed when plectasin was combined with β-lactams (penicillin, amoxicillin or flucloxacillin) in 87-89% of MSSA and MRSA. Interestingly, no such interaction was observed when plectasin was paired with vancomycin. Time kill analysis also demonstrated significant synergistic activities when plectasin was combined with amoxicillin, gentamicin or neomycin. In the murine models, plectasin at doses as low as 8 mg/kg augmented the activities of amoxicillin and gentamicin in successful treatment of MSSA and MRSA infections. We demonstrated that plectasin strongly rejuvenates the therapeutic potencies of existing antibiotics in vitro and in vivo. This is a novel strategy that can have major clinical implications in our fight against bacterial infections
Singularities in scalar-tensor gravity
The analysis of certain singularities in scalar-tensor gravity contained in a
recent paper is completed, and situations are pointed out in which these
singularities cannot occur.Comment: 6 pages, LaTe
Increasing the Neutralino Relic Abundance with Slepton Coannihilations: Consequences for Indirect Dark Matter Detection
We point out that if the lightest supersymmetric particle (LSP) is a
Higgsino- or Wino-like neutralino, the net effect of coannihilations with
sleptons is to increase the relic abundance, rather than producing the usual
suppression, which takes place if the LSP is Bino-like. The reason for the
enhancement lies in the effective thermally averaged cross section at
freeze-out: sleptons annihilate (and co-annihilate) less efficiently than the
neutralino(s)-chargino system, therefore slepton coannihilations effectively
act as parasite degrees of freedom at freeze-out. Henceforth, the thermal relic
abundance of LSP's corresponds to the cold Dark Matter abundance for smaller
values of the LSP mass, and larger values of the neutralino pair annihilation
cross section. In turn, at a given thermal neutralino relic abundance, this
implies larger indirect detection rates, as a result of an increase in the
fluxes of antimatter, gamma rays and neutrinos from the Sun orginating from
neutralino pair annihilations.Comment: 16 pages, 6 figures, references added, typos corrected, matches with
the published versio
Signatures of Baryogenesis in the MSSM
We revisit the electroweak baryogenesis within the context of the minimal
supersymmetric standard model (MSSM), studying its potential collider
signatures. We find that this mechanism of baryogenesis does not give a new CP
violating signal at the -factories. The first circumstantial evidence may
come from enhanced or mixing. If a light right-handed scalar top
and Higgs are found as required, a linear collider represents the best
possibility for confirming the scenario.Comment: 5 pages, 2 figures. Minor typos fixed. Reference Adde
Scherk-Schwarz Supersymmetry Breaking for Quasi-localized Matter Fields and Supersymmetry Flavor Violation
We examine the soft supersymmetry breaking parameters induced by the
Scherk-Schwarz (SS) boundary condition in 5-dimensional orbifold field theory
in which the quark and lepton zero modes are quasi-localized at the orbifold
fixed points to generate the hierarchical Yukawa couplings. In such theories,
the radion corresponds to a flavon to generate the flavor hierarchy and at the
same time plays the role of the messenger of supersymmetry breaking. As a
consequence, the resulting soft scalar masses and trilinear -parameters of
matter zero modes at the compactification scale are highly flavor-dependent,
thereby can lead to dangerous flavor violations at low energy scales. We
analyze in detail the low energy flavor violations in SS-dominated
supersymmetry breaking scenario under the assumption that the compactification
scale is close to the grand unification scale and the 4-dimensional effective
theory below the compactification scale is given by the minimal supersymmetric
standard model. Our analysis can be applied to any supersymmetry breaking
mechanism giving a sizable -component of the radion superfield, e.g. the
hidden gaugino condensation model.Comment: revtex4, 22 pages, some numerical errors are corrected in
phenomenological analysis, main conclusion does not chang
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