Evaluating the risk of non-point source pollution from biosolids: integrated modelling of nutrient losses at field and catchment scales

International audienceA semi-distributed model, INCA, has been developed to determine the fate and distribution of nutrients in terrestrial and aquatic systems. The model simulates nitrogen and phosphorus processes in soils, groundwaters and river systems and can be applied in a semi-distributed manner at a range of scales. In this study, the model has been applied at field to sub-catchment to whole catchment scale to evaluate the behaviour of biosolid-derived losses of P in agricultural systems. It is shown that process-based models such as INCA, applied at a wide range of scales, reproduce field and catchment behaviour satisfactorily. The INCA model can also be used to generate generic information for risk assessment. By adjusting three key variables: biosolid application rates, the hydrological connectivity of the catchment and the initial P-status of the soils within the model, a matrix of P loss rates can be generated to evaluate the behaviour of the model and, hence, of the catchment system. The results, which indicate the sensitivity of the catchment to flow paths, to application rates and to initial soil conditions, have been incorporated into a Nutrient Export Risk Matrix (NERM)

Formation of Disk Galaxies: Warm Dark Matter and the Angular Momentum problem

We have performed TreeSPH simulations of disk galaxy formation in various warm dark matter (WDM) cosmologies. Our results indicate that for a range of WDM free-streaming masses, the disk galaxy formation angular momentum problem can be completely resolved by going to the WDM structure formation scenario, without having to invoke stellar feedback processes at all. We also confirm our previous suspicion, that part of the angular momentum problem is due to numerical effects, most likely related to the shock capturing, artificial viscosity used in SPH. Furthermore we find that we can match the observed I-band Tully-Fisher (TF) relation, provided that the I-band mass-to-light ratio of disk galaxies is about 0.8. We argue that this is quite a reasonable value in comparison with various dynamical and spectrophotometric estimates, including one given in this paper. We speculate that our success in matching the TF relation may be due to WDM halos being less centrally concentrated than CDM halos and suggest to check this exciting possibility with high resolution simulations, in particular in low Omega_M, WDM cosmologies. Finally, we discuss possible physical candidates for WDM particles extensively. We find that the most promising are neutrinos with weaker or stronger interactions than normal, majorons (light pseudogoldstone bosons) or mirror or shadow world neutrinos.Comment: 50 pages incl. 17 figures. Accepted for publication in Ap

Rescattering and chiral dynamics in B\to \rho\pi decay

We examine the role of B^0(\bar B^0) \to \sigma \pi^0 \to \pi^+\pi^- \pi^0 decay in the Dalitz plot analysis of B^0 (\bar B^0) \to \rho\pi \to \pi^+\pi^-\pi^0 decays, employed to extract the CKM parameter \alpha. The \sigma \pi channel is significant because it can break the relationship between the penguin contributions in B\to\rho^0\pi^0, B\to\rho^+\pi^-, and B\to\rho^-\pi^+ decays consequent to an assumption of isospin symmetry. Its presence thus mimics the effect of isospin violation. The \sigma\pi^0 state is of definite CP, however; we demonstrate that the B\to\rho\pi analysis can be generalized to include this channel without difficulty. The \sigma or f_0(400-1200) ``meson'' is a broad I=J=0 enhancement driven by strong \pi\pi rescattering; a suitable scalar form factor is constrained by the chiral dynamics of low-energy hadron-hadron interactions - it is rather different from the relativistic Breit-Wigner form adopted in earlier B\to\sigma\pi and D\to\sigma\pi analyses. We show that the use of this scalar form factor leads to an improved theoretical understanding of the measured ratio Br(\bar B^0 \to \rho^\mp \pi^\pm) / Br(B^-\to \rho^0 \pi^-).Comment: 26 pages, 8 figs, published version. typos fixed, minor change

ELECTROWEAK PENGUINS AND TWO-BODY B DECAYS

We discuss the role of electroweak penguins in $B$ decays to two light pseudoscalar mesons. We confirm that the extraction of the weak phase $\alpha$ through the isospin analysis involving $B\to\pi\pi$ decays is largely unaffected by such operators. However, the methods proposed to obtain weak and strong phases by relating $B\to\pi\pi$, $B\to\pi K$ and $B\to KK$ decays through flavor SU(3) will be invalidated if electroweak penguins are large. We show that, although the introduction of electroweak penguin contributions introduces no new amplitudes of flavor SU(3), there are a number of ways to experimentally measure the size of such effects. Finally, using SU(3) amplitude relations we present a new way of measuring the weak angle $\gamma$ which holds even in the presence of electroweak penguins.Comment: 18 pages, 3 figures, LaTeX file. The full postscript manuscript is available by anonymous ftp at ftp://lpsvsh.lps.umontreal.ca/theorie/hep-ph/EWpenguins.ps (a VAX so use the format theorie.hep-ph if you change by more than one directory at a time

The stellar halo of the Galaxy

Stellar halos may hold some of the best preserved fossils of the formation history of galaxies. They are a natural product of the merging processes that probably take place during the assembly of a galaxy, and hence may well be the most ubiquitous component of galaxies, independently of their Hubble type. This review focuses on our current understanding of the spatial structure, the kinematics and chemistry of halo stars in the Milky Way. In recent years, we have experienced a change in paradigm thanks to the discovery of large amounts of substructure, especially in the outer halo. I discuss the implications of the currently available observational constraints and fold them into several possible formation scenarios. Unraveling the formation of the Galactic halo will be possible in the near future through a combination of large wide field photometric and spectroscopic surveys, and especially in the era of Gaia.Comment: 46 pages, 16 figures. References updated and some minor changes. Full-resolution version available at http://www.astro.rug.nl/~ahelmi/stellar-halo-review.pd

In Vivo and Ex Vivo Evaluation of L-Type Calcium Channel Blockers on Acid β-Glucosidase in Gaucher Disease Mouse Models

Gaucher disease is a lysosomal storage disease caused by mutations in acid β-glucosidase (GCase) leading to defective hydrolysis and accumulation of its substrates. Two L-type calcium channel (LTCC) blockers—verapamil and diltiazem—have been reported to modulate endoplasmic reticulum (ER) folding, trafficking, and activity of GCase in human Gaucher disease fibroblasts. Similarly, these LTCC blockers were tested with cultured skin fibroblasts from homozygous point-mutated GCase mice (V394L, D409H, D409V, and N370S) with the effect of enhancing of GCase activity. Correspondingly, diltiazem increased GCase protein and facilitated GCase trafficking to the lysosomes of these cells. The in vivo effects of diltiazem on GCase were evaluated in mice homozygous wild-type (WT), V394L and D409H. In D409H homozygotes diltiazem (10 mg/kg/d via drinking water or 50–200 mg/kg/d intraperitoneally) had minor effects on increasing GCase activity in brain and liver (1.2-fold). Diltiazem treatment (10 mg/kg/d) had essentially no effect on WT and V394L GCase protein or activity levels (<1.2-fold) in liver. These results show that LTCC blockers had the ex vivo effects of increasing GCase activity and protein in the mouse fibroblasts, but these effects did not translate into similar changes in vivo even at very high drug doses

Introduction: new research in monetary history - A map

This handbook aims to provide a comprehensive (though obviously not exhaustive) picture of state-of-the-art international scholarship on the history of money and currency. The chapters of this handbook cover a wide selection of research topics. They span chronologically from antiquity to nowadays and are geographically stretched from Latin America to Asia, although most of them focus on Western Europe and the USA, as a large part of the existing research does. The authors of these chapters constitute, we hope, a balanced sample of various generations of scholars who contributed to what Barry Eichengreen defined as "the new monetary and financial history" &#8211; an approach that combines the analysis of monetary aggregates and policies with the structure and dynamics of the banking sector and financial markets. We have structured this handbook in ten broad thematic parts: the historical origins of money; money, coinage, and the state; trade, money markets, and international currencies; money and metals; monetary experiments; Asian monetary systems; exchange rate regimes; monetary integration; central banking and monetary policy; and aggregate price shocks. In this introduction, we offer for each part some historical context, a few key insights from the literature, and a brief analytical summary of each chapter. Our aim is to draw a map that hopefully will help readers to organize their journey through this very wide and diverse research area

Paradox as a Metatheoretical Perspective

Organizations are rife with tensions – flexibility vs. control, exploration vs. exploitation, autocracy vs. democracy, social vs. financial, global vs. local. Researchers have long responded using contingency theory, asking “under what conditions should managers emphasize either A or B?” Yet increasingly studies apply a paradox perspective, shifting the question to: “how can we engage both A and B simultaneously?” Despite accumulating exemplars, commonalities across paradox studies remain unclear, and ties unifying this research community weak. To energize further uses of a paradox perspective, we build from past reviews to explicate its role as a metatheory. Contrasting this lens to contingency theory, we illustrate its meta-theoretical nature. We then dive deeper to sharpen the focus and widen the scope of a paradox perspective. Identifying core elements viewed from a paradox perspective – underlying assumptions, central concepts, nature of interrelationships and boundary conditions – offers a guide, informing the practice of paradox research. Next, we illustrate diverse uses of this lens. We conclude by exploring implications and next steps, stressing the rising need for paradox research, as complexity, change and ambiguity intensify demands for both/and approaches in theory and practice