731 research outputs found
Greening Supply Chains in China: Practical Lessons From China-Based Suppliers in Achieving Environmental Performance
Presents case studies of how five China-based suppliers are meeting international buyers' environmental requirements. Examines management processes; effective low-cost ways to reduce water pollution; and the roles of multistakeholders and third parties
Evaluation of Development of Agricultural Modernization in Central China
AbstractBased on multiple-index comprehensive evaluation, the evaluation system of agricultural modernization was constructed, and the level of agricultural modernization in central China was evaluated. As results showed, central China as a whole is still in the beginning stages of the modernization of agriculture, lagging behind the eastern region significantly. To promote agricultural modernization of central China, differently local resource endowments and levels of development on current situation must be considered, and measures should be taken in a line with the local condition and step-by-step, exerting their comparative advantages and selecting the dominant mode, strategic focus and implementation path of agricultural modernization
Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score
Mendelian randomization (MR) is a method of exploiting genetic variation to
unbiasedly estimate a causal effect in presence of unmeasured confounding. MR
is being widely used in epidemiology and other related areas of population
science. In this paper, we study statistical inference in the increasingly
popular two-sample summary-data MR design. We show a linear model for the
observed associations approximately holds in a wide variety of settings when
all the genetic variants satisfy the exclusion restriction assumption, or in
genetic terms, when there is no pleiotropy. In this scenario, we derive a
maximum profile likelihood estimator with provable consistency and asymptotic
normality. However, through analyzing real datasets, we find strong evidence of
both systematic and idiosyncratic pleiotropy in MR, echoing the omnigenic model
of complex traits that is recently proposed in genetics. We model the
systematic pleiotropy by a random effects model, where no genetic variant
satisfies the exclusion restriction condition exactly. In this case we propose
a consistent and asymptotically normal estimator by adjusting the profile
score. We then tackle the idiosyncratic pleiotropy by robustifying the adjusted
profile score. We demonstrate the robustness and efficiency of the proposed
methods using several simulated and real datasets.Comment: 59 pages, 5 figures, 6 table
DC Algorithm for Sample Average Approximation of Chance Constrained Programming: Convergence and Numerical Results
Chance constrained programming refers to an optimization problem with
uncertain constraints that must be satisfied with at least a prescribed
probability level. In this work, we study a class of structured chance
constrained programs in the data-driven setting, where the objective function
is a difference-of-convex (DC) function and the functions in the chance
constraint are all convex. By exploiting the structure, we reformulate it into
a DC constrained DC program. Then, we propose a proximal DC algorithm for
solving the reformulation. Moreover, we prove the convergence of the proposed
algorithm based on the Kurdyka-\L ojasiewicz property and derive the iteration
complexity for finding an approximate KKT point. We point out that the proposed
pDCA and its associated analysis apply to general DC constrained DC programs,
which may be of independent interests. To support and complement our
theoretical development, we show via numerical experiments that our proposed
approach is competitive with a host of existing approaches.Comment: 31 pages, 3 table
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