Light-activated ferroelectric transition in layer dependent Bi2O2Se films

Bi2O2Se has attracted intensive attention due to its potential in electronics, optoelectronics, as well as ferroelectric applications. Despite that, there have only been a handful of experimental studies based on ultrafast spectroscopy to elucidate the carrier dynamics in Bi2O2Se thin films, Different groups have reported various ultrafast timescales and associated mechanisms across films of different thicknesses. A comprehensive understanding in relation to thickness and fluence is still lacking. In this work, we have systematically explored the thickness-dependent Raman spectroscopy and ultrafast carrier dynamics in chemical vapor deposition (CVD)-grown Bi2O2Se thin films on mica substrate with thicknesses varying from 22.44 nm down to 4.62 nm at both low and high pump fluence regions. Combining the thickness dependence and fluence dependence of the slow decay time, we demonstrate a ferroelectric transition in the thinner (< 8 nm) Bi2O2Se films, influenced by substrate-induced compressive strain and non-equilibrium states. Moreover, this transition can be manifested under highly non-equilibrium states. Our results deepen the understanding of the interplay between the ferroelectric phase and semiconducting characteristics of Bi2O2Se thin films, providing a new route to manipulate the ferroelectric transition

Integration of sequence-similarity and functional association information can overcome intrinsic problems in orthology mapping across bacterial genomes

Existing methods for orthologous gene mapping suffer from two general problems: (i) they are computationally too slow and their results are difficult to interpret for automated large-scale applications when based on phylogenetic analyses; or (ii) they are too prone to making mistakes in dealing with complex situations involving horizontal gene transfers and gene fusion due to the lack of a sound basis when based on sequence similarity information. We present a novel algorithm, Global Optimization Strategy (GOST), for orthologous gene mapping through combining sequence similarity and contextual (working partners) information, using a combinatorial optimization framework. Genome-scale applications of GOST show substantial improvements over the predictions by three popular sequence similarity-based orthology mapping programs. Our analysis indicates that our algorithm overcomes the intrinsic issues faced by sequence similarity-based methods, when orthology mapping involves gene fusions and horizontal gene transfers. Our program runs as efficiently as the most efficient sequence similarity-based algorithm in the public domain. GOST is freely downloadable at http://csbl.bmb.uga.edu/~maqin/GOST

Effects of Intranasal Oxytocin on Pup Deprivation-Evoked Aberrant Maternal Behavior and Hypogalactia in Rat Dams and the Underlying Mechanisms

Oxytocin (OT), a hypothalamic neuropeptide, applied through nasal approach (IAO), could improve maternal health during lactation that is disrupted by mother–baby separation; however, the regulation of IAO effects on maternal behaviors and lactation as well as the underlying mechanisms remain unclear. Using lactating rats, we observed effects of intermittent pup deprivation (PD) with and without IAO on maternal behaviors and lactation as well as the activity of OT neurons in the supraoptic nucleus (SON) and the activity of hypothalamic pituitary-adrenal axis, key factors determining the milk-letdown reflex during lactation and maternal behaviors. The results showed that PD reduced maternal behaviors and lactation efficiency of rat dams as indicated by significantly longer latency to retrieve their pups and low litter’s body weight gains during the observation, respectively. In addition, PD caused early involution of the mammary glands. IAO partially improved these changes in rat dams, which was not as significant as IAO effects on control dams. In the SON, PD decreased c-Fos and increased glial fibrillary acidic protein (GFAP) filaments significantly; IAO made PD-evoked c-Fos reduction insignificant while reduced GFAP filament significantly in PD dams. IAO tended to increase the levels of phosphorylated extracellular signal-regulated kinases (pERK) 1/2 in PD dams. Moreover, PD+IAO significantly increased plasma levels of dam adrenocorticotropic hormone and corticosterone but not OT levels. Lastly, PD+IAO tended to increase the level of corticotropin-releasing hormone in the SON. These results indicate that PD disrupts maternal behaviors and lactation by suppressing the activity of hypothalamic OT-secreting system through expansion of astrocytic processes, which are partially reversed by IAO through removing astrocytic inhibition of OT neuronal activity. However, the improving effect of IAO on the maternal health could be compromised by simultaneous activation of hypothalamic pituitary-adrenocortical axis

Research on Road Network Partitioning Considering the Coupling of Network Connectivity and Traffic Attributes

The urban road network is a large and complex system characterized by significant heterogeneity arising from different spatial structures and traffic demands. To facilitate effective management and control, it is necessary to partition the road network into homogeneous sub-areas. In this regard, we aim to propose a hybrid method for partitioning sub-areas with intra-area homogeneity, inter-area heterogeneity, and similar sizes, called CSDRA. It is specifically designed for bidirectional road networks with segment weights that encompass traffic flow, speed, or roadside facility evaluation. Based on community detection and spectral clustering, this proposed method comprises four main modules: initial partition, partitioning of large sub-areas, reassignment of small sub-areas, and boundary adjustment. In the preliminary partitioning work, we also design a road network reconstruction method which further helps to enhance the intra-area homogeneity and inter-area heterogeneity of partitioning results. Furthermore, to align with the requirement for comparable work units in practical traffic management and control, we control the similarity in the size of sub-areas by enforcing upper and lower bound constraints on the size of the sub-areas. We verify the outperformance of the proposed method by an experiment on the partitioning of an urban road network in Guangzhou, China, where we employ sidewalk barrier-free score data as segment weights. The results demonstrate the effectiveness of both the road network reconstruction method and the CSDRA proposed in this paper, as they significantly improve the partitioning outcomes compared with other methods using different evaluation indicators corresponding to the partitioning objectives. Finally, we investigate the influence of constraint parameters on the evaluation indicator. Our findings indicate that appropriately configuring these constraint parameters can effectively minimize sub-region size variations while having minimal impact on other aspects

Advancement of Tidal Current Generation Technology in Recent Years: A Review

Renewable energy provides an effective solution to the problem existing between energy and environmental protection. Tidal energy has great potential as a form of renewable energy. Tidal current generation (TCG) technology is the earliest renewable energy power generation technology. The advancement of science and technology has led to TCG rapidly developing since its emergence in the last century. This paper investigates the development of TCG in recent years based on the key components of TCG systems, both in terms of tidal energy harvesting research and power generation unit research. A summary of tidal energy harvesting is presented, investigating the main tidal energy harvesting units currently available. In addition, research on generators and generator control is summarized. Lastly, a comparison between horizontal and vertical axis turbines is carried out, and predictions are made about the future trends in TCG development. The purpose of this review is to summarize the research status and research methods of key components in tidal energy power generation technology and to provide insight into the research of tidal energy-related technologies