Geo-Social Group Queries with Minimum Acquaintance Constraint

The prosperity of location-based social networking services enables geo-social group queries for group-based activity planning and marketing. This paper proposes a new family of geo-social group queries with minimum acquaintance constraint (GSGQs), which are more appealing than existing geo-social group queries in terms of producing a cohesive group that guarantees the worst-case acquaintance level. GSGQs, also specified with various spatial constraints, are more complex than conventional spatial queries; particularly, those with a strict $k$NN spatial constraint are proved to be NP-hard. For efficient processing of general GSGQ queries on large location-based social networks, we devise two social-aware index structures, namely SaR-tree and SaR*-tree. The latter features a novel clustering technique that considers both spatial and social factors. Based on SaR-tree and SaR*-tree, efficient algorithms are developed to process various GSGQs. Extensive experiments on real-world Gowalla and Dianping datasets show that our proposed methods substantially outperform the baseline algorithms based on R-tree.Comment: This is the preprint version that is accepted by the Very Large Data Bases Journa

Structural failure process of schistosity rock under microwave radiation at high temperatures

The effects of high temperature induced by microwave radiation on the schistosity structural rock were investigated. A 1.45 kW commercial microwave system was employed to irradiate specimens to a designed temperature (300–800 °C) for 15 minutes. Cracking and local melting initially appeared in the biotite enrichment area at 500 °C. Macro-cracks in the dark area were parallel to the schistosity trend, owing to the weak connection in a direction perpendicular to the schistosity plane. The composition of the rock did not significantly change before and after microwave radiation. The diffraction peak intensity of the biotite decreased with temperature increase, owing to melting. The average peak stress decreased significantly with increasing temperature. It is concluded that the high temperature induced by microwave radiation promotes hard rock breakage and the schistosity structure of rock significantly affects the cracking pattern

Defining the threshold: triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio’s non-linear impact on tubular atrophy in primary membranous nephropathy

BackgroundHyperlipidemia is common in primary membranous nephropathy (PMN) patients, and tubular atrophy (TA) is an unfavorable prognostic factor. However, the correlation between the triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and TA is controversial. Therefore, our study aimed to investigate the association between the TG/HDL-C ratio and TA in PMN patients.MethodsWe conducted a cross-sectional study and collected data from 363 PMN patients at Shenzhen Second People’s Hospital from January 2008 to April 2023. The primary objective was to evaluate the independent correlation between the TG/HDL-C ratio and TA using binary logistic regression model. We used a generalized additive model along with smooth curve fitting and multiple sensitivity analyses to explore the relationship between these variables. Additionally, subgroup analyses were conducted to delve deeper into the results.ResultsOf the 363 PMN patients, 75 had TA (20.66%). The study population had a mean age of 46.598 ± 14.462 years, with 217 (59.78%) being male. After adjusting for sex, age, BMI, hypertension, history of diabetes, smoking, alcohol consumption, UPRO, eGFR, HB, FPG, and ALB, we found that the TG/HDL-C ratio was an independent risk factor for TA in PMN patients (OR=1.29, 95% CI: 1.04, 1.61, P=0.0213). A non-linear correlation was observed between the TG/HDL-C ratio and TA, with an inflection point at 4.25. The odds ratios (OR) on the left and right sides of this inflection point were 1.56 (95% CI: 1.17, 2.07) and 0.25 (95% CI: 0.04, 1.54), respectively. Sensitivity analysis confirmed these results. Subgroup analysis showed a consistent association between the TG/HDL-C ratio and TA, implying that factors such as gender, BMI, age, UPRO, ALB, hypertension and severe nephrotic syndrome had negligible effects on the link between the TG/HDL-C ratio and TA.ConclusionOur study demonstrates a non-linear positive correlation between the TG/HDL-C ratio and the risk of TA in PMN patients, independent of other factors. Specifically, the association is more pronounced when the ratio falls below 4.25. Based on our findings, it would be advisable to decrease the TG/HDL-C ratio below the inflection point in PMN patients as part of treatment strategies