Optimal control-based inverse determination of electrode distribution for electroosmotic micromixer

This paper presents an optimal control-based inverse method used to determine the distribution of the electrodes for the electroosmotic micromixers with external driven flow from the inlet. Based on the optimal control method, one Dirichlet boundary control problem is constructed to inversely find the optimal distribution of the electrodes on the sidewalls of electroosmotic micromixers and achieve the acceptable mixing performance. After solving the boundary control problem, the step-shaped distribution of the external electric potential imposed on the sidewalls can be obtained and the distribution of electrodes can be inversely determined according to the obtained external electric potential. Numerical results are also provided to demonstrate the effectivity of the proposed method

Computation Offloading for Edge Computing in RIS-Assisted Symbiotic Radio Systems

In the paper, we investigate the coordination process of sensing and computation offloading in a reconfigurable intelligent surface (RIS)-aided base station (BS)-centric symbiotic radio (SR) systems. Specifically, the Internet-of-Things (IoT) devices first sense data from environment and then tackle the data locally or offload the data to BS for remote computing, while RISs are leveraged to enhance the quality of blocked channels and also act as IoT devices to transmit its sensed data. To explore the mechanism of cooperative sensing and computation offloading in this system, we aim at maximizing the total completed sensed bits of all users and RISs by jointly optimizing the time allocation parameter, the passive beamforming at each RIS, the transmit beamforming at BS, and the energy partition parameters for all users subject to the size of sensed data, energy supply and given time cycle. The formulated nonconvex problem is tightly coupled by the time allocation parameter and involves the mathematical expectations, which cannot be solved straightly. We use Monte Carlo and fractional programming methods to transform the nonconvex objective function and then propose an alternating optimization-based algorithm to find an approximate solution with guaranteed convergence. Numerical results show that the RIS-aided SR system outperforms other benchmarks in sensing. Furthermore, with the aid of RIS, the channel and system performance can be significantly improved.Comment: 13 pages, 7 figure

Dibromido[1,1′-dibenzyl-2,2′-(sulfane­diyl­dimethyl­ene)di-1H-benzimidazole]­cadmium(II) dimethyl­formamide solvate

In the title compound, [CdBr2(C30H26N4S)]·C3H7NO, both the complex and solvent mol­ecule lie on a crystallographic mirror plane. The CdII ion is coordinated in a disorted square-pyramidal CdBr2N2S environment with one of the Br atoms in the apical site. In the crystal structure, the benzimidazole ring systems are involved in weak inter­molecular π–π stacking inter­actions [centroid–centroid distances = 3.606 (2) and 3.753 (2) Å]. Further stabilization is provided by weak inter­molecular C—H⋯O hydrogen bonds. The methyl H atoms of the dimethyl­formamide solvent mol­ecule are disordered about a mirror plane

sTarPicker: A Method for Efficient Prediction of Bacterial sRNA Targets Based on a Two-Step Model for Hybridization

Bacterial sRNAs are a class of small regulatory RNAs involved in regulation of expression of a variety of genes. Most sRNAs act in trans via base-pairing with target mRNAs, leading to repression or activation of translation or mRNA degradation. To date, more than 1,000 sRNAs have been identified. However, direct targets have been identified for only approximately 50 of these sRNAs. Computational predictions can provide candidates for target validation, thereby increasing the speed of sRNA target identification. Although several methods have been developed, target prediction for bacterial sRNAs remains challenging.Here, we propose a novel method for sRNA target prediction, termed sTarPicker, which was based on a two-step model for hybridization between an sRNA and an mRNA target. This method first selects stable duplexes after screening all possible duplexes between the sRNA and the potential mRNA target. Next, hybridization between the sRNA and the target is extended to span the entire binding site. Finally, quantitative predictions are produced with an ensemble classifier generated using machine-learning methods. In calculations to determine the hybridization energies of seed regions and binding regions, both thermodynamic stability and site accessibility of the sRNAs and targets were considered. Comparisons with the existing methods showed that sTarPicker performed best in both performance of target prediction and accuracy of the predicted binding sites.sTarPicker can predict bacterial sRNA targets with higher efficiency and determine the exact locations of the interactions with a higher accuracy than competing programs. sTarPicker is available at http://ccb.bmi.ac.cn/starpicker/