Probing triple-Higgs productions via 4b2γ4b2\gamma decay channel at a 100 TeV hadron collider

The quartic self-coupling of the Standard Model Higgs boson can only be measured by observing the triple-Higgs production process, but it is challenging for the Large Hadron Collider (LHC) Run 2 or International Linear Collider (ILC) at a few TeV because of its extremely small production rate. In this paper, we present a detailed Monte Carlo simulation study of the triple-Higgs production through gluon fusion at a 100 TeV hadron collider and explore the feasibility of observing this production mode. We focus on the decay channel $HHH\rightarrow b\bar{b}b\bar{b}\gamma\gamma$, investigating detector effects and optimizing the kinematic cuts to discriminate the signal from the backgrounds. Our study shows that, in order to observe the Standard Model triple-Higgs signal, the integrated luminosity of a 100 TeV hadron collider should be greater than $1.8\times 10^4$ ab$^{-1}$. We also explore the dependence of the cross section upon the trilinear ($\lambda_3$) and quartic ($\lambda_4$) self-couplings of the Higgs. We find that, through a search in the triple-Higgs production, the parameters $\lambda_3$ and $\lambda_4$ can be restricted to the ranges $[-1, 5]$ and $[-20, 30]$, respectively. We also examine how new physics can change the production rate of triple-Higgs events. For example, in the singlet extension of the Standard Model, we find that the triple-Higgs production rate can be increased by a factor of $\mathcal{O}(10)$.Comment: 33 pages, 11 figures, added references, corrected typos, improved text, affiliation is changed. This is the publication versio

Prospects of gravitational waves in the minimal left-right symmetric model

The left-right symmetric model (LRSM) is a well-motivated framework to restore parity and implement seesaw mechanisms for the tiny neutrino masses at or above the TeV-scale, and has a very rich phenomenology at both the high-energy and high-precision frontiers. In this paper we examine the phase transition and resultant gravitational waves (GWs) in the minimal version of LRSM. Taking into account all the theoretical and experimental constraints on LRSM, we identify the parameter regions with strong first-order phase transition and detectable GWs in the future experiments. It turns out in a sizeable region of the parameter space, GWs can be generated in the phase transition with the strength of $10^{-17}$ to $10^{-12}$ at the frequency of 0.1 to 10 Hz, which can be detected by BBO and DECIGO. Furthermore, GWs in the LRSM favor a relatively light $SU(2)_R$-breaking scalar $H_3^0$, which is largely complementary to the direct searches of a long-lived neutral scalar at the high-energy colliders. It is found that the other heavy scalars and the right-handed neutrinos in the LRSM also play an important part for GW signal production in the phase transition.Comment: 41 pages, 10 figures, 5 tables, added references, improved tex

Constraining rare B decays by μ+μ−→tc\mu^+\mu^-\to tc at future lepton colliders

Motivated by the recent rare B decays measurements, we study the matching procedure of operators $O_9, O_{10}$ in the low energy effective Hamiltonian and operators in the Standard Model effective theory (SMEFT). It is noticed that there are more related operators in the SMEFT whose coefficients can not be determined only from the low-energy data from B physics. We demonstrate how to determine these coefficients with some new physics models, like $Z^\prime$ model and leptoquark models, and then consider how to probe these operators of SMEFT at high energy by using the process $\mu^+\mu^-\to tc$ at future muon colliders, which can provide complementary information except for $\mu^+ \mu^- \to b s$ on the underlying models which lead to rare B decay processes. We perform a Monte Carlo study (a hadron level analysis) to show how to separate the signal events from the SM background events and estimate the sensitivity to the Wilson coefficients for different models.Comment: 29 pages, 8 figures, 3 tables, added references, publication versio

Gravitational waves from axion wave production

We consider a scenario with axions/axion-like particles Chern-Simons gravity coupling, such that gravitational waves can be produced directly from axion wave tachyonic instability in the early universe after inflation. This axion gravity term is less constrained compared to the well-searched axion photon coupling and can provide a direct and efficient production channel for gravitational waves. Such stochastic gravitational waves can be detected by either space/ground-based gravitational wave detectors or pulsar timing arrays for a broad range of axion masses and decay constants.Comment: 13 pages, 4 figure

Spatial and Modal Optimal Transport for Fast Cross-Modal MRI Reconstruction

Multi-modal magnetic resonance imaging (MRI) plays a crucial role in comprehensive disease diagnosis in clinical medicine. However, acquiring certain modalities, such as T2-weighted images (T2WIs), is time-consuming and prone to be with motion artifacts. It negatively impacts subsequent multi-modal image analysis. To address this issue, we propose an end-to-end deep learning framework that utilizes T1-weighted images (T1WIs) as auxiliary modalities to expedite T2WIs' acquisitions. While image pre-processing is capable of mitigating misalignment, improper parameter selection leads to adverse pre-processing effects, requiring iterative experimentation and adjustment. To overcome this shortage, we employ Optimal Transport (OT) to synthesize T2WIs by aligning T1WIs and performing cross-modal synthesis, effectively mitigating spatial misalignment effects. Furthermore, we adopt an alternating iteration framework between the reconstruction task and the cross-modal synthesis task to optimize the final results. Then, we prove that the reconstructed T2WIs and the synthetic T2WIs become closer on the T2 image manifold with iterations increasing, and further illustrate that the improved reconstruction result enhances the synthesis process, whereas the enhanced synthesis result improves the reconstruction process. Finally, experimental results from FastMRI and internal datasets confirm the effectiveness of our method, demonstrating significant improvements in image reconstruction quality even at low sampling rates

How to Face COVID-19 in Ophthalmology Practice

Background: The novel coronavirus pneumonia has attracted considerable attention from the international community. With the spread of outbreaks around the world, the WHO characterized COVID-19 as a pandemic. Methods: Relevant studies in PubMed were searched from January 1, 2020 to April 12, 2020, using the following search strategy: (“novel coronavirus pneumonia†OR “severe acute respiratory syndrome coronavirus 2†OR “coronavirus disease 2019†OR “COVID-19†OR “novel coronavirus pneumoniaâ€) AND (“ophthalmology†OR “ophthalmologist†OR “eye†OR “conjunctiva†OR “conjunctivitis†OR “corneal†OR “keratitisâ€). Results: SARS-CoV-2 can spread through aerosol and is detected in tears of patients with COVID-19 infection. Notably, some infected patients had conjunctivitis, and conjunctivitis was the first symptom in some patients later diagnosed to have COVID-19 infection. This would increase the risk for ophthalmologists through inpatient consultations or regular clinical practice. When dealing with seemingly regular ophthalmic patients, the vigilance of ophthalmologists and associated staff tends to be reduced. Conclusion: Ophthalmologists must continuously update their knowledge regarding COVID-19 and take effective measures to prevent COVID-19 transmission