Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries

BACKGROUND: Pancreatic surgery remains associated with high morbidity rates. Although postoperative mortality appears to have improved with specialization, the outcomes reported in the literature reflect the activity of highly specialized centres. The aim of this study was to evaluate the outcomes following pancreatic surgery worldwide. METHODS: This was an international, prospective, multicentre, cross-sectional snapshot study of consecutive patients undergoing pancreatic operations worldwide in a 3-month interval in 2021. The primary outcome was postoperative mortality within 90 days of surgery. Multivariable logistic regression was used to explore relationships with Human Development Index (HDI) and other parameters. RESULTS: A total of 4223 patients from 67 countries were analysed. A complication of any severity was detected in 68.7 per cent of patients (2901 of 4223). Major complication rates (Clavien–Dindo grade at least IIIa) were 24, 18, and 27 per cent, and mortality rates were 10, 5, and 5 per cent in low-to-middle-, high-, and very high-HDI countries respectively. The 90-day postoperative mortality rate was 5.4 per cent (229 of 4223) overall, but was significantly higher in the low-to-middle-HDI group (adjusted OR 2.88, 95 per cent c.i. 1.80 to 4.48). The overall failure-to-rescue rate was 21 per cent; however, it was 41 per cent in low-to-middle- compared with 19 per cent in very high-HDI countries. CONCLUSION: Excess mortality in low-to-middle-HDI countries could be attributable to failure to rescue of patients from severe complications. The authors call for a collaborative response from international and regional associations of pancreatic surgeons to address management related to death from postoperative complications to tackle the global disparities in the outcomes of pancreatic surgery (NCT04652271; ISRCTN95140761

Call Me When You Grow Up: Firms’ Age, Size, and IPO Performance across Sectors

We provide a fresh look at the performance of the stock prices of firms that launched an IPO between 2009 and 2019 and assess the role of their size, age and sector in affecting future performance. We utilize data about 1611 IPOs spanning 11 economic sectors using the event study method. We provide evidence that a firm’s size and age do act as predictors for its price evolution in the future. In addition, there is a significant variation in the long-term performance between sectors and between small and large firms within each sector. Furthermore, there is a clear tendency of firms from sectors such as healthcare and technology to go public at a relatively younger age than other sectors. The results have implications for asset pricing and are useful for investors involved in IPOs

Call me when you grow up: Firms' age, size, and IPO performance across sectors

We provide a fresh look at the performance of the stock prices of firms that launched an IPO between 2009 and 2019 and assess the role of their size, age and sector in affecting future performance. We utilize data about 1611 IPOs spanning 11 economic sectors using the event study method. We provide evidence that a firm's size and age do act as predictors for its price evolution in the future. In addition, there is a significant variation in the long-term performance between sectors and between small and large firms within each sector. Furthermore, there is a clear tendency of firms from sectors such as healthcare and technology to go public at a relatively younger age than other sectors. The results have implications for asset pricing and are useful for investors involved in IPOs

The Complexity of Cryptocurrencies Algorithmic Trading

In this research, we provided an answer to a very important trading question, what is the optimal number of technical tools in order to achieve the best trading results for both swing trade that uses daily bars and intraday trade that uses minutes bars? We designed Machine Learning (ML) systems that can trade four major cryptocurrencies: Bitcoin, Ethereum, BNB, and Solana. We found that more indicators do not necessarily mean better trading performance. Swing traders that use daily bars should trade Bitcoin and Solana using Ichimoku Cloud (IC) plus Moving Average Convergence Divergence (MACD), Ethereum with IC plus Chaikin Money Flow (CMF), and BNB with IC alone. With regard to intraday trading, we documented that different cryptocurrencies should be trading using different time frames. These results emphasize that the optimal number of indicators that are used to trade daily bars is one or, at maximum, two. The Multi-Layer (MUL) system that consists of all three examined technical indicators failed to improve the trading results for both days (swing) and intraday trades. The main implication of this study for traders is that more indicators does not necessarily improve trades performances

The Information Conveyed in a SPAC′s Offering

The popularity of SPACs (Special Purpose Acquisition Companies) has grown dramatically in recent years as a substitute for the traditional IPO (Initial Public Offer). We modeled the average annual return for SPAC investors and found that this financial tool produced an annual return of 17.3%. We then constructed an information model that examined a SPAC′s excess returns during the 60 days after a potential merger or acquisition had been announced. We found that the announcement had a major impact on the SPAC’s share price over the 60 days, delivering on average 0.69% daily excess returns over the IPO portfolio and 31.6% cumulative excess returns for the entire period. Relative to IPOs, the cumulative excess returns of SPACs rose dramatically in the next few days after the potential merger or acquisition announcement until the 26th day. They then declined but rose again until the 48th day after the announcement. Finally, the SPAC’s structure reduced the investors’ risk. Thus, if investors buy a SPAC stock immediately after a potential merger or acquisition has been announced and hold it for 48 days, they can reap substantial short-term returns

The Complexity of Cryptocurrencies Algorithmic Trading

In this research, we provided an answer to a very important trading question, what is the optimal number of technical tools in order to achieve the best trading results for both swing trade that uses daily bars and intraday trade that uses minutes bars? We designed Machine Learning (ML) systems that can trade four major cryptocurrencies: Bitcoin, Ethereum, BNB, and Solana. We found that more indicators do not necessarily mean better trading performance. Swing traders that use daily bars should trade Bitcoin and Solana using Ichimoku Cloud (IC) plus Moving Average Convergence Divergence (MACD), Ethereum with IC plus Chaikin Money Flow (CMF), and BNB with IC alone. With regard to intraday trading, we documented that different cryptocurrencies should be trading using different time frames. These results emphasize that the optimal number of indicators that are used to trade daily bars is one or, at maximum, two. The Multi-Layer (MUL) system that consists of all three examined technical indicators failed to improve the trading results for both days (swing) and intraday trades. The main implication of this study for traders is that more indicators does not necessarily improve trades performances

Forecasting Commodity Prices Using the Term Structure

The aim of this study is to test the ability of the yield curve on US government bonds to forecast the future evolution in the prices of commodities often used in as raw materials. We consider the monthly prices of nine commodities for more than 30 years. Our findings, confirmed by several parametric and non-parametric tests, are robust and indicate that the ability to forecast future performance changes over time. Specifically, between 1986 and the early 2000s the yield curve was quite successful in forecasting monthly changes in commodity prices, but that success diminished in the period following. One possible explanation for this outcome is the increased flow of capital into the commodity market resulting in stronger correlations with the equity markets and a breakdown of the obvious relationship between commodities and business cycle. Our findings are important for asset pricing, commodity traders and policy makers

Forecasting commodity prices using the term structure

The aim of this study is to test the ability of the yield curve on US government bonds to forecast the future evolution in the prices of commodities often used in as raw materials. We consider the monthly prices of nine commodities for more than 30 years. Our findings, confirmed by several parametric and non-parametric tests, are robust and indicate that the ability to forecast future performance changes over time. Specifically, between 1986 and the early 2000s the yield curve was quite successful in forecasting monthly changes in commodity prices, but that success diminished in the period following. One possible explanation for this outcome is the increased flow of capital into the commodity market resulting in stronger correlations with the equity markets and a breakdown of the obvious relationship between commodities and business cycle. Our findings are important for asset pricing, commodity traders and policy makers

Tell Me Why I Do Not Like Mondays

We conduct a strict and broad analysis of the 30-day expected volatility (VIX) of five very active individual US stocks, three US domestic indices, and that of 10-year US Treasury notes. We find prominent non-random movement patterns mainly on Mondays and Fridays. Furthermore, significant leaps in expected volatility on Monday occur primarily in the first two and the fifth Mondays of the month. We also document that higher values for the 30-day expected volatility on Mondays are more likely when there was a negative change in the volatility on the preceding Fridays. This pattern does not occur on other subsequent days of the week. The results are robust through time and different subsamples and are not triggered by outliers or the week during which the options on the underlying assets expire. Rational and irrational drivers are suggested to explain the findings. Given that, to date, no one has conducted such an examination, our findings are important for investors interested in buying or selling volatility instruments