19 research outputs found

    Energy Management and Time Scheduling for Heterogeneous IoT Wireless-Powered Backscatter Networks

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    © 2019 IEEE. In this paper, we propose a novel approach to jointly address energy management and network throughput maximization problems for heterogeneous IoT low-power wireless communication networks. In particular, we consider a low-power communication network in which the IoT devices can harvest energy from a dedicated RF energy source to support their transmissions or backscatter the signals of the RF energy source to transmit information to the gateway. Different IoT devices may have dissimilar hardware configurations, and thus they may have various communications types and energy requirements. In addition, the RF energy source may have a limited energy supply source which needs to be minimized. Thus, to maximize the network throughput, we need to jointly optimize energy usage and operation time for the IoT devices under different energy demands and communication constraints. However, this optimization problem is non-convex due to the strong relation between energy supplied by the RF energy source and the IoT communication time, and thus obtaining the optimal solution is intractable. To address this problem, we study the relation between energy supply and communication time, and then transform the non-convex optimization problem to an equivalent convex-optimization problem which can achieve the optimal solution. Through simulation results, we show that our solution can achieve greater network throughputs (up to five times) than those of other conventional methods, e.g., TDMA. In addition, the simulation results also reveal some important information in controlling energy supply and managing low-power IoT devices in heterogeneous wireless communication networks

    Complete genome characterization of two wild-type measles viruses from Vietnamese infants during the 2014 outbreak

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    A large measles virus outbreak occurred across Vietnam in 2014. We identified and obtained complete measles virus genomes in stool samples collected from two diarrheal pediatric patients in Dong Thap Province. These are the first complete genome sequences of circulating measles viruses in Vietnam during the 2014 measles outbreak

    Genome sequences of a novel Vietnamese bat bunyavirus

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    To document the viral zoonotic risks in Vietnam, fecal samples were systematically collected from a number of mammals in southern Vietnam and subjected to agnostic deep sequencing. We describe here novel Vietnamese bunyavirus sequences detected in bat feces. The complete L and S segments from 14 viruses were determined

    Strict Frequency Reuse in Ultra Dense Networks

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    © 2018 IEEE. In this paper, the Ultra Dense Network (UDN) using Strict Frequency Reuse (FR) is modelled according to the 3GPP recommendations. The recent developed stretch path loss model is utilised to replace the traditional one. The user performance expressions in terms of user classification probability and average coverage probability are derived in Rayleigh fading environment. Throughout the analytical results, which are verified by Monte Carlo simulation, the new findings are presented such as in deep fading environment, the received signal strength at the user keeps constant when the transmit power of Base Station (BS) varies; when the density of BSs increases, the Cell-Center User (CCU) performance reduces continuously while Cell-Edge User (CEU) performance fluctuates

    Energy Trading and Time Scheduling for Energy-Efficient Heterogeneous Low-Power IoT Networks

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    In this paper, an economic model is proposed to jointly optimize profits for participants in a heterogeneous IoT wireless-powered backscatter communication network. In the network under considerations, a power beacon and IoT devices (with various communication types and energy constraints) are assumed to belong to different service providers, i.e., energy service provider (ESP) and IoT service provider (ISP), respectively. To jointly maximize the utility for both service providers in terms of energy efficiency and network throughput, a Stackelberg game model is proposed to study the strategic interaction between the ISP and ESP. In particular, the ISP first evaluates its benefits from providing IoT services to its customers and then sends its requested price together with the service time to the ESP. Based on the request from the ISP, the ESP offers an optimized transmission power that maximizes its utility while meeting energy demands of the ISP. To study the Stackelberg equilibrium, we first obtain a closed-form solution for the ESP and propose a low-complexity iterative method based on block coordinate descent (BCD) to address the non-convex optimization problem for the ISP. Through simulation results, we show that our approach can significantly improve the profits for both providers compared with those of conventional transmission methods, e.g., bistatic backscatter and harvest-then-transmit communication methods

    Assessing the efficacy and safety of magnesium sulfate for management of autonomic nervous system dysregulation in Vietnamese children with severe hand foot and mouth disease

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    BACKGROUND:Brainstem encephalitis is a serious complication of hand foot and mouth disease (HFMD) in children. Autonomic nervous system (ANS) dysregulation and hypertension may occur, sometimes progressing to cardiopulmonary failure and death. Vietnamese national guidelines recommend use of milrinone if ANS dysregulation with Stage 2 hypertension develops. We wished to investigate whether magnesium sulfate (MgSO4) improved outcomes in children with HFMD if used earlier in the evolution of the ANS dysregulation (Stage 1 hypertension). METHODS:During a regional epidemic we conducted a randomized, double-blind, placebo-controlled trial of MgSO4 in children with HFMD, ANS dysregulation and Stage 1 hypertension, at the Hospital for Tropical Diseases in Ho Chi Minh city. Study participants received an infusion of MgSO4 or matched placebo for 72 h. We also reviewed data from non-trial HFMD patients in whom milrinone failed to control hypertension, some of whom received MgSO4 as second line therapy. The primary outcome for both analyses was a composite of disease progression within 72 h - addition of milrinone (trial participants only), need for ventilation, shock, or death. RESULTS:Between June 2014 and September 2016, 14 and 12 participants received MgSO4 or placebo respectively, before the trial was stopped due to futility. Among 45 non-trial cases with poorly controlled hypertension despite high-dose milrinone, 33 received MgSO4 while 12 did not. There were no statistically significant differences in the composite outcome between the MgSO4 and the placebo/control groups in either study (adjusted relative risk (95%CI) of [6/14 (43%) vs. 6/12 (50%)], 0.84 (0.37, 1.92), p = 0.682 in the trial and [1/33 (3%) vs. 2/12 (17%)], 0.16 (0.01, 1.79), p = 0.132 in the observational cohort). The incidence of adverse events was similar between the groups. Potentially toxic magnesium levels occurred very rarely with the infusion regime used. CONCLUSION:Although we could not demonstrate efficacy in these studies, there were no safety signals associated with use of 30-50 mg/kg/hr. MgSO4 in severe HFMD. Intermittent outbreaks of HFMD are likely to continue across the region, and an adequately powered trial is still needed to evaluate use of MgSO4 in controlling hypertension in severe HFMD, potentially involving a higher dose regimen. TRIAL REGISTRATION:ClinicalTrials.gov Identifier: NCT01940250 (Registered 22 AUG 2013). Trial sponsor: University of Oxford

    Assessing the efficacy and safety of magnesium sulfate for management of autonomic nervous system dysregulation in Vietnamese children with severe hand foot and mouth disease

    No full text
    BACKGROUND:Brainstem encephalitis is a serious complication of hand foot and mouth disease (HFMD) in children. Autonomic nervous system (ANS) dysregulation and hypertension may occur, sometimes progressing to cardiopulmonary failure and death. Vietnamese national guidelines recommend use of milrinone if ANS dysregulation with Stage 2 hypertension develops. We wished to investigate whether magnesium sulfate (MgSO4) improved outcomes in children with HFMD if used earlier in the evolution of the ANS dysregulation (Stage 1 hypertension). METHODS:During a regional epidemic we conducted a randomized, double-blind, placebo-controlled trial of MgSO4 in children with HFMD, ANS dysregulation and Stage 1 hypertension, at the Hospital for Tropical Diseases in Ho Chi Minh city. Study participants received an infusion of MgSO4 or matched placebo for 72 h. We also reviewed data from non-trial HFMD patients in whom milrinone failed to control hypertension, some of whom received MgSO4 as second line therapy. The primary outcome for both analyses was a composite of disease progression within 72 h - addition of milrinone (trial participants only), need for ventilation, shock, or death. RESULTS:Between June 2014 and September 2016, 14 and 12 participants received MgSO4 or placebo respectively, before the trial was stopped due to futility. Among 45 non-trial cases with poorly controlled hypertension despite high-dose milrinone, 33 received MgSO4 while 12 did not. There were no statistically significant differences in the composite outcome between the MgSO4 and the placebo/control groups in either study (adjusted relative risk (95%CI) of [6/14 (43%) vs. 6/12 (50%)], 0.84 (0.37, 1.92), p = 0.682 in the trial and [1/33 (3%) vs. 2/12 (17%)], 0.16 (0.01, 1.79), p = 0.132 in the observational cohort). The incidence of adverse events was similar between the groups. Potentially toxic magnesium levels occurred very rarely with the infusion regime used. CONCLUSION:Although we could not demonstrate efficacy in these studies, there were no safety signals associated with use of 30-50 mg/kg/hr. MgSO4 in severe HFMD. Intermittent outbreaks of HFMD are likely to continue across the region, and an adequately powered trial is still needed to evaluate use of MgSO4 in controlling hypertension in severe HFMD, potentially involving a higher dose regimen. TRIAL REGISTRATION:ClinicalTrials.gov Identifier: NCT01940250 (Registered 22 AUG 2013). Trial sponsor: University of Oxford

    Effect of the optimize heart failure care program on clinical and patient outcomes – The pilot implementation in Vietnam

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    Background: The Ho-Chi-Minh-city Heart Institute in Vietnam took part in the Optimize Heart Failure (OHF) Care Program, designed to improve outcomes following heart failure (HF) hospitalization by increasing patient awareness and optimizing HF treatment. Methods: HF patients hospitalized with left ventricular ejection-fraction (LVEF) <50% were included. Patients received guideline-recommended HF treatment and education. Clinical signs, treatments and outcomes were assessed at admission, discharge, 2 and 6 months (M2, M6). Patients’ knowledge and practice were assessed at M6 by telephone survey. Results: 257 patients were included. Between admission and M2 and M6, heart rate decreased significantly, and clinical symptoms improved significantly. LVEF increased significantly from admission to M6. 85% to 99% of patients received education. At M6, 45% to 78% of patients acquired knowledge and adhered to practice regarding diet, exercise, weight control, and detection of worsening symptoms. High use of renin-angiotensin-aldosterone-system inhibitors (91%), mineralocorticoid-receptor-antagonists (77%) and diuretics (85%) was noted at discharge. Beta-blocker and ivabradine use was less frequent at discharge but increased significantly at M6 (from 33% to 51% and from 9% to 20%, respectively, p < 0.001). There were no in-hospital deaths. Readmission rates at 30 and 60 days after discharge were 8.3% and 12.5%, respectively. Mortality rates at 30 days, 60 days and 6 months were 1.2%, 2.5% and 6.4%, respectively. Conclusions: The OHF Care Program could be implemented in Vietnam without difficulty and was associated with high usage of guideline-recommended drug therapy. Although education was delivered, patient knowledge and practice could be further improved at M6 after discharge
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