20 research outputs found
Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract
Get PDFNuclear cataract is the most common type of age-related cataract and a leading cause of blindness worldwide. Age-related nuclear cataract is heritable (h2 = 0.48), but little is known about specific genetic factors underlying this condition. Here we report findings from the largest to date multi-ethnic meta-analysis of genome-wide association studies (discovery cohort N = 14,151 and replication N = 5299) of the International Cataract Genetics Consortium. We confirmed the known genetic association of CRYAA (rs7278468, P = 2.8 × 10−16) with nuclear cataract and identified five new loci associated with this disease: SOX2-OT (rs9842371, P = 1.7 × 1
Transition from oceanic subduction to continental collision in central Tibet: evidence from the Cretaceous magmatism in Qiangtang block
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Early Jurassic metamorphism of the eastern segment of the Lhasa terrane in South Tibet and its tectonic significance
No full textChitooligosaccharide supplementation improves the reproductive performance and milk composition of sows
No full textConfinement and localization effects revealed for thin films of the miscible blend poly(vinyl methyl ether)/polystyrene with a composition of 25/75 wt%⋆
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