The significance of adolescent social competence for mental health in young adulthood

Publisher Copyright: © 2021Introduction: Social competence is one of the primary components of mental health development. This study examines the associations between adolescent competence and its components, and adulthood adaptive functioning and internalizing and externalizing problems. Methods: As part of a longitudinal study that begun in Finland in 1989, 191 mothers, 126 fathers and their 192 16–17-year-old adolescent children completed a standardized questionnaire, the Child Behavior Checklist or the Youth Self Report, to analyse the adolescents’ total competence and its subscales (activity, social skills and school performance). Ten years later, the former adolescents completed the corresponding Adult Self Report questionnaire to assess adaptive functioning as well as internalizing and externalizing symptoms. Results: Better total competence or social skills in adolescence were associated with a good level of adaptive functioning and a low level of internalizing symptoms in young adulthood. Better scores in school performance subscale according to the parents’ reports were associated with a low level of externalizing symptoms in young adulthood. Together with total competence and social skills, concurrent partner relationship status was associated with optimal outcomes. Conclusion: This study supports earlier findings that better social competence in adolescence is associated with fewer internalizing problems in young adulthood, and indicates a longitudinal association between adolescent competence and adult adaptive functioning. It is important to study whether interventions supporting adolescents’ competence could promote mental health in their subsequent development into young adulthood.Peer reviewe

Evaluation of Long-term LiDAR Place Recognition

We compare a state-of-the-art deep image retrieval and a deep place recognition method for place recognition using LiDAR data. Place recognition aims to detect previously visited locations and thus provides an important tool for navigation, mapping, and localisation. Experimental comparisons are conducted using challenging outdoor and indoor datasets, Oxford Radar RobotCar and COLD, in the "long-term" setting where the test conditions differ substantially from the training and gallery data. Based on our results the image retrieval methods using LiDAR depth images can achieve accurate localization (the single best match recall 80%) within 5.00 m in urban outdoors. In office indoors the comparable accuracy is 50 cm but is more sensitive to changes in the environment.acceptedVersionPeer reviewe

Associations between cooperation, reactive aggression and social impairments among boys with autism spectrum disorder

Cooperation is a fundamental human ability that seems to be inversely related to aggressive behaviour in typical development. However, there is no knowledge whether similar association holds for children with autism spectrum disorder. A total of 27 boys with autism spectrum disorder and their gender, age and total score intelligence matched controls were studied in order to determine associations between cooperation, reactive aggression and autism spectrum disorder–related social impairments. The participants performed a modified version of the Prisoner’s Dilemma task and the Pulkkinen Aggression Machine which measure dimensions of trust, trustworthiness and self-sacrifice in predisposition to cooperate, and inhibition of reactive aggression in the absence and presence of situational cues, respectively. Autism spectrum disorder severity–related Autism Diagnostic Interview-algorithm scores were ascertained by interviewing the parents of the participants with a semi-structured parental interview (Developmental, Dimensional and Diagnostic Interview). The results showed that albeit the boys with autism spectrum disorder were able to engage in reciprocation and cooperation regardless of their social impairments, their cooperativeness was positively associated with lower levels of reactive aggression and older age. Thus, strengthening inhibition mechanisms that regulate reactive aggression might make boys with autism spectrum disorder more likely to prefer mutual gain over self-interest in cooperation

Strong Association of De Novo Copy Number Mutations with Autism

We tested the hypothesis that de novo copy number variation (CNV) is associated with autism spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on the genomic DNA of patients and unaffected subjects to detect copy number variants not present in their respective parents. Candidate genomic regions were validated by higher-resolution CGH, paternity testing, cytogenetics, fluorescence in situ hybridization, and microsatellite genotyping. Confirmed de novo CNVs were significantly associated with autism (P = 0.0005). Such CNVs were identified in 12 out of 118 (10%) of patients with sporadic autism, in 2 out of 77 (3%) of patients with an affected first-degree relative, and in 2 out of 196 (1%) of controls. Most de novo CNVs were smaller than microscopic resolution. Affected genomic regions were highly heterogeneous and included mutations of single genes. These findings establish de novo germline mutation as a more significant risk factor for ASD than previously recognized

What makes health visiting successful – or not? 1. Universality

The altered landscape surrounding commissioning of public health provision has affected the nature and range of health visitor services across England. This is the first of two papers reporting evidence from a programme of research that focused on how health visiting works, also reporting service user and workforce perspectives. Evidence for a service model is offered, based on universal principles and maximising the capacity of the health visiting resource. Where service specifications fail to give careful attention to this evidence, the reshaped services for children and families may miss core ingredients that enable health visitors to make a difference, delivering a proportionate and successful child health programme for the early years

Microduplications of 16p11.2 are associated with schizophrenia

Recurrent microdeletions and microduplications of a 600-kb genomic region of chromosome 16p11.2 have been implicated in childhood-onset developmental disorders1,2,3. We report the association of 16p11.2 microduplications with schizophrenia in two large cohorts. The microduplication was detected in 12/1,906 (0.63%) cases and 1/3,971 (0.03%) controls (P = 1.2 × 10−5, OR = 25.8) from the initial cohort, and in 9/2,645 (0.34%) cases and 1/2,420 (0.04%) controls (P = 0.022, OR = 8.3) of the replication cohort. The 16p11.2 microduplication was associated with a 14.5-fold increased risk of schizophrenia (95% CI (3.3, 62)) in the combined sample. A meta-analysis of datasets for multiple psychiatric disorders showed a significant association of the microduplication with schizophrenia (P = 4.8 × 10−7), bipolar disorder (P = 0.017) and autism (P = 1.9 × 10−7). In contrast, the reciprocal microdeletion was associated only with autism and developmental disorders (P = 2.3 × 10−13). Head circumference was larger in patients with the microdeletion than in patients with the microduplication (P = 0.0007)