55 research outputs found
Buoyancy-induced flow and heat transfer in compressor rotors
The buoyancy-induced flow and heat transfer inside the compressor rotors of gas-turbine engines affects the stresses and radial growth of the compressor disks, and it also causes a temperature rise in the axial throughflow of cooling air through the center of the disks. In turn, the radial growth of the disks affects the radial clearance between the rotating compressor blades and the surrounding stationary casing. The calculation of this clearance is extremely important, particularly in aeroengines where the increase in pressure ratios results in a decrease in the size of the blades. In this paper, a published theoretical modelâbased on buoyancy-induced laminar Ekman-layer flow on the rotating disksâis extended to include laminar free convection from the compressor shroud and forced convection between the bore of the disks and the axial throughflow. The predicted heat transfer from these three surfaces is then used to calculate the temperature rise of the throughflow. The predicted temperatures and Nusselt numbers are compared with measurements made in a multicavity compressor rig, and mainly good agreement is achieved for a range of Rossby, Reynolds, and Grashof numbers representative of those found in aeroengine compressors. Owing to compressibility effects in the fluid core between the disksâand as previously predictedâincreasing rotational speed can result in an increase in the core temperature and a consequent decrease in the Nusselt numbers from the disks and shroud
UWB Microwave Imaging for Inclusions Detection: Methodology for Comparing Artefact Removal Algorithms
An investigation is presented on Artefact Removal Methods for Ultra-Wideband (UWB) Microwave Imaging. Simulations have been done representing UWB signals transmitted onto a cylindrical head-mimicking phantom containing an inclusion having dielectric properties imitating an haemorrhagic stroke. The ideal image is constructed by applying a Huygensâ Principle based imaging algorithm to the difference between the electric field outside the cylinder with an inclusion and the electric field outside the same cylinder with no inclusion. Eight different artefact removal methods are then applied, with the inclusion positioned at \u1d70b and â\u1d70b/4 radians, respectively. The ideal image is then used as a reference image to compare the artefact removal methods employing a novel Image Quality Index, calculated using a weighted combination of image quality metrics. The Summed Symmetric Differential method performed very well in our simulations
Developing Artefact Removal Algorithms to Process Data from a Microwave Imaging Device for Haemorrhagic Stroke Detection
In this paper, we present an investigation of different artefact removal methods for ultra-wideband Microwave Imaging (MWI) to evaluate and quantify current methods in a real environment through measurements using an MWI device. The MWI device measures the scattered signals in a multi-bistatic fashion and employs an imaging procedure based on Huygens principle. A simple two-layered phantom mimicking human head tissue is realised, applying a cylindrically shaped inclusion to emulate brain haemorrhage. Detection has been successfully achieved using the superimposition of five transmitter triplet positions, after applying different artefact removal methods, with the inclusion positioned at 0°, 90°, 180°, and 270°. The different artifact removal methods have been proposed for comparison to improve the stroke detection process. To provide a valid comparison between these methods, image quantification metrics are presented. An âideal/referenceâ image is used to compare the artefact removal methods. Moreover, the quantification of artefact removal procedures through measurements using MWI device is performed
Positive coexistence of water voles and beaver: water vole expansion in a beaver engineered wetland
This is the final version. Available on open access from the Mammal Society via the DOI in this recordWater voles (Arvicola amphibius) are critically endangered in Great Britain and there is a pressing need for successful conservation strategies. Meanwhile, another semi-aquatic rodent, the Eurasian beaver (Castor fiber) is being restored to much of its native range including Great Britain. Beavers are known as ecosystem engineers and keystone species, creating wetland habitats. As part of the River Otter Beaver Trial in South-West England, free-living beavers were reintroduced in a location where water vole were present and being surveyed. Here, we present survey data showing the expansion of water vole into newly beaver engineered wetland areas. We propose that complex beaver wetlands may benefit water vole populations by creating new habitat and providing refuge from predation, warranting further investigation as a nature recovery option
A wireless sensor network-based approach to large-scale dimensional metrology
In many branches of industry, dimensional measurements have become an important part of the production cycle, in order to check product compliance with specifications. This task is not trivial especially when dealing with largescale dimensional measurements: the bigger the measurement dimensions are, the harder is to achieve high accuracies. Nowadays, the problem can be handled using many metrological systems, based on different technologies (e.g. optical, mechanical, electromagnetic). Each of these systems is more or less adequate, depending upon measuring conditions, user's experience and skill, or other factors such as time, cost, accuracy and portability. This article focuses on a new possible approach to large-scale dimensional metrology based on wireless sensor networks. Advantages and drawbacks of such approach are analysed and deeply discussed. Then, the article briefly presents a recent prototype system - the Mobile Spatial Coordinate-Measuring System (MScMS-II) - which has been developed at the Industrial Metrology and Quality Laboratory of DISPEA - Politecnico di Torino. The system seems to be suitable for performing dimensional measurements of large-size objects (sizes on the order of several meters). Owing to its distributed nature, the system - based on a wireless network of optical devices - is portable, fully scalable with respect to dimensions and shapes and easily adaptable to different working environments. Preliminary results of experimental tests, aimed at evaluating system performance as well as research perspectives for further improvements, are discusse
Modelling Eurasian Beaver Foraging Habitat and Dam Suitability, for Predicting the Location and Number of Dams Throughout Catchments in Great Britain
Eurasian beaver (Castor fiber) populations are expanding across Europe. Depending on location, beaver dams bring multiple benefits and/or require management. Using nationally available data, we developed: a Beaver Forage Index (BFI), identifying beaver foraging habitat, and a Beaver Dam Capacity (BDC) model, classifying suitability of river reaches for dam construction, to estimate location and number of dams at catchment scales. Models were executed across three catchments, in Great Britain (GB), containing beaver. An area of 6747 km2 was analysed for BFI and 16,739 km of stream for BDC. Field surveys identified 258 km of channel containing beaver activity and 89 dams, providing data to test predictions. Models were evaluated using a categorical binomial Bayesian framework to calculate probability of foraging and dam construction. BFI and BDC models successfully categorised the use of reaches for foraging and damming, with higher scoring reaches being preferred. Highest scoring categories were ca. 31 and 79 times more likely to be used than the lowest for foraging and damming respectively. Zero-inflated negative binomial regression showed that modelled dam capacity was significantly related (pâ=â0.01) to observed damming and was used to predict numbers of dams that may occur. Estimated densities of dams, averaged across each catchment, ranged from 0.4 to 1.6 dams/km, though local densities may be up to 30 dams/km. These models provide fundamental information describing the distribution of beaver foraging habitat, where dams may be constructed and how many may occur. This supports the development of policy and management concerning the reintroduction and recolonisation of beaver
Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis
: Recent studies have shown that the tumor extracellular matrix (ECM) associates with immunosuppression, and that targeting the ECM can improve immune infiltration and responsiveness to immunotherapy. A question that remains unresolved is whether the ECM directly educates the immune phenotypes seen in tumors. Here, we identify a tumor-associated macrophage (TAM) population associated with poor prognosis, interruption of the cancer immunity cycle, and tumor ECM composition. To investigate whether the ECM was capable of generating this TAM phenotype, we developed a decellularized tissue model that retains the native ECM architecture and composition. Macrophages cultured on decellularized ovarian metastasis shared transcriptional profiles with the TAMs found in human tissue. ECM-educated macrophages have a tissue-remodeling and immunoregulatory phenotype, inducing altered T cell marker expression and proliferation. We conclude that the tumor ECM directly educates this macrophage population found in cancer tissues. Therefore, current and emerging cancer therapies that target the tumor ECM may be tailored to improve macrophage phenotype and their downstream regulation of immunity
Sensitivity of fluvial sediment source apportionment to mixing model assumptions: A Bayesian model comparison
Mixing models have become increasingly common tools for apportioning fluvial sediment load to various sediment sources across catchments using a wide variety of Bayesian and frequentist modeling approaches. In this study, we demonstrate how different model setups can impact upon resulting source apportionment estimates in a Bayesian framework via a one-factor-at-a-time (OFAT) sensitivity analysis. We formulate 13 versions of a mixing model, each with different error assumptions and model structural choices, and apply them to sediment geochemistry data from the River Blackwater, Norfolk, UK, to apportion suspended particulate matter (SPM) contributions from three sources (arable topsoils, road verges, and subsurface material) under base flow conditions between August 2012 and August 2013. Whilst all 13 models estimate subsurface sources to be the largest contributor of SPM (median âŒ76%), comparison of apportionment estimates reveal varying degrees of sensitivity to changing priors, inclusion of covariance terms, incorporation of time-variant distributions, and methods of proportion characterization. We also demonstrate differences in apportionment results between a full and an empirical Bayesian setup, and between a Bayesian and a frequentist optimization approach. This OFAT sensitivity analysis reveals that mixing model structural choices and error assumptions can significantly impact upon sediment source apportionment results, with estimated median contributions in this study varying by up to 21% between model versions. Users of mixing models are therefore strongly advised to carefully consider and justify their choice of model structure prior to conducting sediment source apportionment investigations
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