Supplementary Material for: Internet-Delivered Disease Management for Recurrent Depression: A Multicenter Randomized Controlled Trial

<b><i>Background:</i></b> Strategies to improve the life of patients suffering from recurrent major depression have a high relevance. This study examined the efficacy of 2 Internet-delivered augmentation strategies that aim to prolong symptom-free intervals. <b><i>Methods:</i></b> Efficacy was tested in a 3-arm, multicenter, open-label, evaluator-blind, randomized controlled trial. Upon discharge from inpatient mental health care, 232 adults with 3 or more major depressive episodes were randomized to 1 of 2 intervention groups (SUMMIT or SUMMIT-PERSON) or to treatment as usual (TAU) alone. Over 12 months, participants in both intervention arms received, in addition to TAU, intense monitoring via e-mail or a smartphone, including signaling of upcoming crises, assistance with personal crisis management, and facilitation of early intervention. SUMMIT-PERSON additionally offered regular expert chats. The primary outcome was ‘well weeks', i.e. weeks with at most mild symptoms assessed by the Longitudinal Interval Follow-Up Evaluation, during 24 months after the index treatment. <b><i>Results:</i></b> SUMMIT compared to TAU reduced the time with an unwell status (OR 0.48; 95% CI 0.23-0.98) through faster transitions from unwell to well (OR 1.44; 95% CI 0.83-2.50) and slower transitions from well to unwell (OR 0.69; 95% CI 0.44-1.09). Contrary to the hypothesis, SUMMIT-PERSON was not superior to either SUMMIT (OR 0.77; 95% CI 0.38-1.56) or TAU (OR 0.62; 95% CI 0.31-1.24). The efficacy of SUMMIT was strongest 8 months after the intervention. <b><i>Conclusions:</i></b> The fully automated Internet-delivered augmentation strategy SUMMIT has the potential to improve TAU by reducing the lifelong burden of patients with recurrent depression. The fact that the effects wear off suggests a time-unlimited extension

Entwicklung eines Verfahrens zur Aufstellung umweltorientierter Fernverkehrskonzepte als Beitrag zur Bundesverkehrswegeplanung Schlussbericht

In the project a procedure for planning an environmentally sustainable transport system as part of the federal transport infrastructure planning has been developed and applied in a case study for Baden-Wuerttemberg. The starting point for the procedure are politically defined environmental goals. Transport policy scenarios are designed and evaluated, until one of these scenarios achieves the given goals and generates economically optical results. A bridge is built between network level assessments and project orientated cost-benefit analysis by deriving shadow prices from the design of a sustainable transport system which can be used for an economic evaluation of projects. For this, the present cost values applied in the economic assessment for the federal transport plan have been enhanced by costs for tropospheric ozone, carcinogenic substances, outdoor noise as well as nature and landscape. In the case study a basic scenario 1992 as well as a trend scenario and two succeeding frame scenarios 2010 have been evaluated on the basis of the transport networks in the German state of Baden-Wuerttemberg. The results of frame scenario 2 reveal that the defined environmental goals can be achieved mainly by technological measures and modal shifts due to improved infrastructure supply and regulatory policy instruments. The case study has shown that an intermodal and network-wide assessment of the environmental impacts of transport infrastructure projects is possible, which allows for an integration of environmental regards into the early stages of transport planning. (orig.)SIGLEAvailable from TIB Hannover: RN 8908(98-058) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekUmweltbundesamt, Berlin (Germany); Bundesministerium fuer Umwelt, Naturschutz und Reaktorsicherheit, Bonn (Germany)DEGerman

The present: an "unknown time" in the German Kaiserreich around 1900

In her contribution, Rothauge focuses on assumptions of ‘the present’ in the German Kaiserreich around 1900. Historical sources reveal that many contemporaries considered present time(s) to be highly dynamic and heterogeneous, thus confusing and partly ‘unknown’. Rothauge links this to several official initiatives preoccupied with synchronising different time regimes. She argues that these attempts initially led to a yet again increased pluralisation of both the notions and uses of ‘the present’. According to this, the master narrative of (high) modernity as being characterised by just one specific temporal experience, namely that of an ever increasing acceleration, needs to be looked at in a more differentiated way, paying more attention to the fact that people actively take part in the construction of temporal discourses