2,508 research outputs found
Intelligent Based Terrain Preview Controller for a 3-axle Vehicle
Presented at 13th International Symposium on Advanced Vehicle Control, AVEC'16; Munich 13-16/09/2016The paper presents a six-wheel half longitudinal model and the design of a dual level control architecture. The first (top) level is designed using a Sugeno fuzzy inference feedforward architecture with and without preview. The second level of controllers are locally managing each wheel for each axle. As the vehicle is moving forward the front wheels and suspension units will have less time to respond when compared to the middle and rear units, hence a preview sensor is used to compensate. The paper shows that the local active suspensions together with the Sugeno Fuzzy, (locally optimised using subtractive clustering), Feedforward control strategy is more effective and this architecture has resulted in reducing the sprung mass vertical acceleration and pitch accelerations
Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance
Background A fundamental feature of early nervous system development is the guidance of axonal projections to their targets in order to assemble neural circuits that control behavior. Spinal commissural neurons are an attractive model to investigate the multiple guidance cues that control growth cone navigation both pre- and post-midline crossing, as well as along both the dorsal–ventral (D–V) and anterior–posterior (A–P) axes. Accumulating evidence suggests that guidance of spinal commissural axons along the A–P axis is dependent on components of the planar cell polarity (PCP) signaling pathway. In the zebrafish, the earliest born spinal commissural neuron to navigate the midline and turn rostrally is termed commissural primary ascending (CoPA). Unlike mammalian systems, CoPA axons cross the midline as a single axon and allow an analysis of the role of PCP components in anterior pathfinding in single pioneering axons. Results Here, we establish CoPA cells in the zebrafish spinal cord as a model system for investigating the molecular function of planar cell polarity signaling in axon guidance. Using mutant analysis, we show that the functions of Fzd3a and Vangl2 in the anterior turning of commissural axons are evolutionarily conserved in teleosts. We extend our findings to reveal a role for the PCP gene scribble in the anterior guidance of CoPA axons. Analysis of single CoPA axons reveals that these commissural axons become responsive to PCP-dependent anterior guidance cues even prior to midline crossing. When midline crossing is prevented by dcc gene knockdown, ipsilateral CoPA axons still extend axons anteriorly in response to A–P guidance cues. We show that this ipsilateral anterior pathfinding that occurs in the absence of midline crossing is dependent on PCP signaling. Conclusion Our results demonstrate that anterior guidance decisions by CoPA axons are dependent on the function of planar cell polarity genes both prior to and after midline crossing
A Bichromatic Incidence Bound and an Application
We prove a new, tight upper bound on the number of incidences between points
and hyperplanes in Euclidean d-space. Given n points, of which k are colored
red, there are O_d(m^{2/3}k^{2/3}n^{(d-2)/3} + kn^{d-2} + m) incidences between
the k red points and m hyperplanes spanned by all n points provided that m =
\Omega(n^{d-2}). For the monochromatic case k = n, this was proved by Agarwal
and Aronov.
We use this incidence bound to prove that a set of n points, no more than n-k
of which lie on any plane or two lines, spans \Omega(nk^2) planes. We also
provide an infinite family of counterexamples to a conjecture of Purdy's on the
number of hyperplanes spanned by a set of points in dimensions higher than 3,
and present new conjectures not subject to the counterexample.Comment: 12 page
Cavity optomechanics with Si3N4 membranes at cryogenic temperatures
We describe a cryogenic cavity-optomechanical system that combines Si3N4
membranes with a mechanically-rigid Fabry-Perot cavity. The extremely high
quality-factor frequency products of the membranes allow us to cool a MHz
mechanical mode to a phonon occupation of less than 10, starting at a bath
temperature of 5 kelvin. We show that even at cold temperatures
thermally-occupied mechanical modes of the cavity elements can be a limitation,
and we discuss methods to reduce these effects sufficiently to achieve ground
state cooling. This promising new platform should have versatile uses for
hybrid devices and searches for radiation pressure shot noise.Comment: 19 pages, 5 figures, submitted to New Journal of Physic
Determinants of blood pressure control in rural KwaZulu-Natal, South Africa
Background: Hypertension is a common problem in South Africa and is known to be inadequately treated and poorly controlled. Objectives: The objective of the study was to investigate what proportion of patients prescribed antihypertensive medication had controlled blood pressure (BP) and to identify factors associated with poor control. Method: In May and June 2012, clinic-attending adults who had been prescribed antihypertensive medication were recruited into this cross-sectional study. A questionnaire administered by field assistants investigated participants’ socio-demographic characteristics, medical history, perception of health, use of traditional healers, illness perceptions, beliefs about medication, compliance with the medication and suggestions as to how to improve hypertensive treatment. BP measurements were taken. Logistic regression analysis identified the determinants of poor BP control. Results: Of the 500 participants, the mean age was 58 years, 78% were female and the majority had never been to school, or had only attended primary school. One third had adequately controlled BP ( 140/90 mmHg). Factors associated with poor BP control included being prescribed more than one antihypertensive medication, self-reported asthma and poor compliance with the medication, although the latter was not significant after adjusting for other variables. Participants with diabetes and those with a family history of a stroke were more likely to have good BP control. Conclusion: Only one third of participants had adequately controlled BP, and almost half did not understand their high BP at all. Many had concerns about taking medication, but most felt that it was necessary. Participants suggested that better health education and ensuring that medication was available in the clinics could improve BP control
Bose-Einstein condensation in a circular waveguide
We have produced Bose-Einstein condensates in a ring-shaped magnetic
waveguide. The few-millimeter diameter non-zero bias ring is formed from a
time-averaged quadrupole ring. Condensates which propagate around the ring make
several revolutions within the time it takes for them to expand to fill the
ring. The ring shape is ideally suited for studies of vorticity in a
multiply-connected geometry and is promising as a rotation sensor.Comment: 4 pages, 4 figure
Tunable Cavity Optomechanics with Ultracold Atoms
We present an atom-chip-based realization of quantum cavity optomechanics
with cold atoms localized within a Fabry-Perot cavity. Effective sub-wavelength
positioning of the atomic ensemble allows for tuning the linear and quadratic
optomechanical coupling parameters, varying the sensitivity to the displacement
and strain of a compressible gaseous cantilever. We observe effects of such
tuning on cavity optical nonlinearity and optomechanical frequency shifts,
providing their first characterization in the quadratic-coupling regime.Comment: 4 pages, 5 figure
- …
